| Full name: PDLIM1 interacting kinase 1 like | Alias Symbol: CLIK1L | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 149420 | HGNC ID: HGNC:18981 | Ensembl Gene: ENSG00000175087 | OMIM ID: 610785 |
| Drug and gene relationship at DGIdb | |||
Expression of PDIK1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDIK1L | 149420 | 227255_at | 0.0995 | 0.9107 | |
| GSE26886 | PDIK1L | 149420 | 227255_at | -1.8699 | 0.0000 | |
| GSE45670 | PDIK1L | 149420 | 227255_at | -0.1613 | 0.3542 | |
| GSE53622 | PDIK1L | 149420 | 8645 | -0.3276 | 0.0029 | |
| GSE53624 | PDIK1L | 149420 | 37007 | -0.3100 | 0.0000 | |
| GSE63941 | PDIK1L | 149420 | 227255_at | 0.2354 | 0.6629 | |
| GSE77861 | PDIK1L | 149420 | 227255_at | -0.5170 | 0.0093 | |
| GSE97050 | PDIK1L | 149420 | A_33_P3302280 | 0.1972 | 0.5783 | |
| SRP007169 | PDIK1L | 149420 | RNAseq | -0.3513 | 0.4952 | |
| SRP008496 | PDIK1L | 149420 | RNAseq | -0.3431 | 0.2162 | |
| SRP064894 | PDIK1L | 149420 | RNAseq | -0.2702 | 0.0838 | |
| SRP133303 | PDIK1L | 149420 | RNAseq | -0.0811 | 0.6839 | |
| SRP159526 | PDIK1L | 149420 | RNAseq | -0.1483 | 0.5884 | |
| SRP193095 | PDIK1L | 149420 | RNAseq | -0.5518 | 0.0000 | |
| SRP219564 | PDIK1L | 149420 | RNAseq | -0.3310 | 0.3667 | |
| TCGA | PDIK1L | 149420 | RNAseq | -0.0421 | 0.5167 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PDIK1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDIK1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDIK1L | 149420 | 0 | 6 | 24 | |
| GSE20123 | PDIK1L | 149420 | 0 | 5 | 25 | |
| GSE43470 | PDIK1L | 149420 | 2 | 6 | 35 | |
| GSE46452 | PDIK1L | 149420 | 5 | 1 | 53 | |
| GSE47630 | PDIK1L | 149420 | 8 | 3 | 29 | |
| GSE54993 | PDIK1L | 149420 | 2 | 1 | 67 | |
| GSE54994 | PDIK1L | 149420 | 10 | 4 | 39 | |
| GSE60625 | PDIK1L | 149420 | 0 | 0 | 11 | |
| GSE74703 | PDIK1L | 149420 | 1 | 4 | 31 | |
| GSE74704 | PDIK1L | 149420 | 0 | 0 | 20 | |
| TCGA | PDIK1L | 149420 | 9 | 24 | 63 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of PDIK1L:
Generating mutation plots.
Highly correlated genes for PDIK1L:
Showing top 20/852 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDIK1L | GTF2A1 | 0.844884 | 3 | 0 | 3 |
| PDIK1L | SAMD8 | 0.799022 | 3 | 0 | 3 |
| PDIK1L | SMC3 | 0.793566 | 3 | 0 | 3 |
| PDIK1L | OXNAD1 | 0.789057 | 3 | 0 | 3 |
| PDIK1L | SLC10A7 | 0.779693 | 3 | 0 | 3 |
| PDIK1L | ERCC6 | 0.773646 | 4 | 0 | 4 |
| PDIK1L | SMURF1 | 0.772742 | 3 | 0 | 3 |
| PDIK1L | PPP2CB | 0.764177 | 3 | 0 | 3 |
| PDIK1L | RNF146 | 0.758069 | 3 | 0 | 3 |
| PDIK1L | BRWD1 | 0.757761 | 3 | 0 | 3 |
| PDIK1L | HIPK1 | 0.756009 | 4 | 0 | 3 |
| PDIK1L | ATP6V1B2 | 0.755032 | 3 | 0 | 3 |
| PDIK1L | MLKL | 0.752527 | 3 | 0 | 3 |
| PDIK1L | ARRDC3 | 0.751491 | 3 | 0 | 3 |
| PDIK1L | BRWD3 | 0.750812 | 3 | 0 | 3 |
| PDIK1L | TRIM6 | 0.748666 | 3 | 0 | 3 |
| PDIK1L | SLMAP | 0.747346 | 3 | 0 | 3 |
| PDIK1L | SGMS2 | 0.745859 | 3 | 0 | 3 |
| PDIK1L | PSENEN | 0.745295 | 3 | 0 | 3 |
| PDIK1L | DHX32 | 0.743935 | 3 | 0 | 3 |
For details and further investigation, click here
