| Full name: ubinuclein 2 | Alias Symbol: FLJ25778|KIAA2030 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 254048 | HGNC ID: HGNC:21931 | Ensembl Gene: ENSG00000157741 | OMIM ID: 613841 |
| Drug and gene relationship at DGIdb | |||
Expression of UBN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBN2 | 254048 | 225445_at | -0.1939 | 0.7266 | |
| GSE26886 | UBN2 | 254048 | 225445_at | -1.2176 | 0.0000 | |
| GSE45670 | UBN2 | 254048 | 225445_at | -0.1713 | 0.3400 | |
| GSE63941 | UBN2 | 254048 | 225445_at | 0.0651 | 0.9330 | |
| GSE77861 | UBN2 | 254048 | 225445_at | 0.0908 | 0.7617 | |
| GSE97050 | UBN2 | 254048 | A_33_P3339231 | -0.0875 | 0.6575 | |
| SRP007169 | UBN2 | 254048 | RNAseq | 0.5757 | 0.1376 | |
| SRP008496 | UBN2 | 254048 | RNAseq | 0.5194 | 0.0308 | |
| SRP064894 | UBN2 | 254048 | RNAseq | -0.2050 | 0.3547 | |
| SRP133303 | UBN2 | 254048 | RNAseq | -0.1284 | 0.2993 | |
| SRP159526 | UBN2 | 254048 | RNAseq | -0.3932 | 0.1772 | |
| SRP193095 | UBN2 | 254048 | RNAseq | -0.3141 | 0.0028 | |
| SRP219564 | UBN2 | 254048 | RNAseq | -0.4527 | 0.1610 | |
| TCGA | UBN2 | 254048 | RNAseq | -0.1117 | 0.0279 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBN2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of UBN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBN2 | 254048 | 5 | 2 | 23 | |
| GSE20123 | UBN2 | 254048 | 5 | 2 | 23 | |
| GSE43470 | UBN2 | 254048 | 2 | 3 | 38 | |
| GSE46452 | UBN2 | 254048 | 7 | 2 | 50 | |
| GSE47630 | UBN2 | 254048 | 7 | 4 | 29 | |
| GSE54993 | UBN2 | 254048 | 3 | 5 | 62 | |
| GSE54994 | UBN2 | 254048 | 5 | 8 | 40 | |
| GSE60625 | UBN2 | 254048 | 0 | 0 | 11 | |
| GSE74703 | UBN2 | 254048 | 2 | 3 | 31 | |
| GSE74704 | UBN2 | 254048 | 1 | 2 | 17 | |
| TCGA | UBN2 | 254048 | 28 | 23 | 45 |
Total number of gains: 65; Total number of losses: 54; Total Number of normals: 369.
Somatic mutations of UBN2:
Generating mutation plots.
Highly correlated genes for UBN2:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBN2 | NICN1 | 0.780967 | 3 | 0 | 3 |
| UBN2 | CYP2E1 | 0.765958 | 3 | 0 | 3 |
| UBN2 | BUD13 | 0.73886 | 3 | 0 | 3 |
| UBN2 | TRPS1 | 0.738046 | 3 | 0 | 3 |
| UBN2 | TMEM217 | 0.736215 | 3 | 0 | 3 |
| UBN2 | YIPF1 | 0.735863 | 3 | 0 | 3 |
| UBN2 | FBXO34 | 0.735424 | 4 | 0 | 4 |
| UBN2 | PARS2 | 0.721988 | 3 | 0 | 3 |
| UBN2 | ZNF682 | 0.698127 | 4 | 0 | 3 |
| UBN2 | DNAJC16 | 0.696108 | 4 | 0 | 4 |
| UBN2 | SLC37A1 | 0.692631 | 4 | 0 | 3 |
| UBN2 | FAM221A | 0.692348 | 3 | 0 | 3 |
| UBN2 | SNX31 | 0.689738 | 3 | 0 | 3 |
| UBN2 | CLN3 | 0.686848 | 3 | 0 | 3 |
| UBN2 | KIAA1671 | 0.681462 | 3 | 0 | 3 |
| UBN2 | CROT | 0.676346 | 4 | 0 | 3 |
| UBN2 | VILL | 0.676093 | 4 | 0 | 4 |
| UBN2 | SHOC2 | 0.670504 | 4 | 0 | 3 |
| UBN2 | FAM3B | 0.669975 | 3 | 0 | 3 |
| UBN2 | STX19 | 0.664046 | 3 | 0 | 3 |
For details and further investigation, click here
