GABPB2

 

Full name: GA binding protein transcription factor subunit beta 2 Alias Symbol: MGC29891
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 126626 HGNC ID: HGNC:28441 Ensembl Gene: ENSG00000143458 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of GABPB2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GABPB2 126626 228466_at -0.5536 0.4277
GSE26886 GABPB2 126626 228466_at -0.7285 0.0003
GSE45670 GABPB2 126626 228466_at 0.0125 0.9656
GSE53622 GABPB2 126626 127488 -0.8775 0.0000
GSE53624 GABPB2 126626 127488 -0.5946 0.0000
GSE63941 GABPB2 126626 228466_at -0.3812 0.5985
GSE77861 GABPB2 126626 228466_at -0.0224 0.9389
GSE97050 GABPB2 126626 A_23_P73208 -0.5115 0.3051
SRP007169 GABPB2 126626 RNAseq -0.5059 0.3140
SRP008496 GABPB2 126626 RNAseq 0.5611 0.1753
SRP064894 GABPB2 126626 RNAseq -0.2377 0.1845
SRP133303 GABPB2 126626 RNAseq -0.0621 0.7045
SRP159526 GABPB2 126626 RNAseq 0.2831 0.1168
SRP193095 GABPB2 126626 RNAseq -0.0113 0.9244
SRP219564 GABPB2 126626 RNAseq 0.0897 0.8072
TCGA GABPB2 126626 RNAseq -0.0128 0.8805

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GABPB2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GABPB2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GABPB2 126626 14 0 16
GSE20123 GABPB2 126626 14 0 16
GSE43470 GABPB2 126626 6 1 36
GSE46452 GABPB2 126626 2 1 56
GSE47630 GABPB2 126626 14 0 26
GSE54993 GABPB2 126626 0 4 66
GSE54994 GABPB2 126626 15 0 38
GSE60625 GABPB2 126626 0 0 11
GSE74703 GABPB2 126626 6 1 29
GSE74704 GABPB2 126626 7 0 13
TCGA GABPB2 126626 37 2 57

Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.  


 

Somatic mutations of GABPB2:

 

Generating mutation plots.

 

Highly correlated genes for GABPB2:

 

Showing top 20/99 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GABPB2TTC170.775228303
GABPB2PAXBP10.69248303
GABPB2NR2C20.692238303
GABPB2BCOR0.664764403
GABPB2SOD10.654476303
GABPB2SERPINB60.653804403
GABPB2ERCC6L20.652913303
GABPB2ITSN20.648625403
GABPB2TF0.641522403
GABPB2TARM10.637441303
GABPB2PHACTR40.629993403
GABPB2ALDH9A10.629671504
GABPB2NLRP80.624896303
GABPB2DCLK10.623151303
GABPB2TBRG10.617787303
GABPB2ZNF6820.611613303
GABPB2KIAA02320.611455403
GABPB2FCHO20.60951403
GABPB2PEBP10.609137303
GABPB2SIAE0.608926303

For details and further investigation, click here