| Full name: histone deacetylase 6 | Alias Symbol: KIAA0901|JM21|HD6|FLJ16239|PPP1R90 | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 10013 | HGNC ID: HGNC:14064 | Ensembl Gene: ENSG00000094631 | OMIM ID: 300272 |
| Drug and gene relationship at DGIdb | |||
Expression of HDAC6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDAC6 | 10013 | 206846_s_at | 0.0026 | 0.9972 | |
| GSE20347 | HDAC6 | 10013 | 206846_s_at | -0.1502 | 0.2541 | |
| GSE23400 | HDAC6 | 10013 | 206846_s_at | -0.1625 | 0.0006 | |
| GSE26886 | HDAC6 | 10013 | 206846_s_at | -0.3628 | 0.0070 | |
| GSE29001 | HDAC6 | 10013 | 206846_s_at | -0.1756 | 0.4349 | |
| GSE38129 | HDAC6 | 10013 | 206846_s_at | -0.1632 | 0.1363 | |
| GSE45670 | HDAC6 | 10013 | 206846_s_at | 0.0807 | 0.6792 | |
| GSE53622 | HDAC6 | 10013 | 24655 | -0.2830 | 0.0001 | |
| GSE53624 | HDAC6 | 10013 | 24655 | -0.3651 | 0.0000 | |
| GSE63941 | HDAC6 | 10013 | 206846_s_at | 0.4558 | 0.1575 | |
| GSE77861 | HDAC6 | 10013 | 206846_s_at | -0.2519 | 0.0863 | |
| GSE97050 | HDAC6 | 10013 | A_23_P250455 | -0.2619 | 0.2372 | |
| SRP007169 | HDAC6 | 10013 | RNAseq | -0.7568 | 0.0387 | |
| SRP008496 | HDAC6 | 10013 | RNAseq | -0.9268 | 0.0000 | |
| SRP064894 | HDAC6 | 10013 | RNAseq | 0.1808 | 0.1986 | |
| SRP133303 | HDAC6 | 10013 | RNAseq | -0.2329 | 0.2011 | |
| SRP159526 | HDAC6 | 10013 | RNAseq | 0.0884 | 0.8129 | |
| SRP193095 | HDAC6 | 10013 | RNAseq | -0.3479 | 0.0004 | |
| SRP219564 | HDAC6 | 10013 | RNAseq | -0.0740 | 0.7710 | |
| TCGA | HDAC6 | 10013 | RNAseq | -0.0753 | 0.1502 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HDAC6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDAC6:
No record found for this gene.
Somatic mutations of HDAC6:
Generating mutation plots.
Highly correlated genes for HDAC6:
Showing top 20/283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDAC6 | ATXN7L3B | 0.778679 | 3 | 0 | 3 |
| HDAC6 | GNAS | 0.771656 | 3 | 0 | 3 |
| HDAC6 | COPS7A | 0.770876 | 3 | 0 | 3 |
| HDAC6 | NDUFS3 | 0.747102 | 3 | 0 | 3 |
| HDAC6 | SPHK2 | 0.743929 | 3 | 0 | 3 |
| HDAC6 | MPND | 0.740758 | 3 | 0 | 3 |
| HDAC6 | GYS1 | 0.724226 | 3 | 0 | 3 |
| HDAC6 | FAM53B | 0.711097 | 3 | 0 | 3 |
| HDAC6 | CSNK1D | 0.710364 | 4 | 0 | 4 |
| HDAC6 | DNAJB12 | 0.707342 | 3 | 0 | 3 |
| HDAC6 | RAB1B | 0.705788 | 3 | 0 | 3 |
| HDAC6 | IPO8 | 0.70184 | 3 | 0 | 3 |
| HDAC6 | SRRM1 | 0.701477 | 3 | 0 | 3 |
| HDAC6 | CHID1 | 0.700518 | 3 | 0 | 3 |
| HDAC6 | SLC25A23 | 0.697434 | 3 | 0 | 3 |
| HDAC6 | RCOR3 | 0.688606 | 3 | 0 | 3 |
| HDAC6 | APLP2 | 0.688212 | 3 | 0 | 3 |
| HDAC6 | SOS1 | 0.680557 | 3 | 0 | 3 |
| HDAC6 | LSP1 | 0.678997 | 3 | 0 | 3 |
| HDAC6 | STK40 | 0.67617 | 4 | 0 | 3 |
For details and further investigation, click here
