| Full name: G kinase anchoring protein 1 | Alias Symbol: GKAP42|FKSG21 | ||
| Type: protein-coding gene | Cytoband: 9q21.32 | ||
| Entrez ID: 80318 | HGNC ID: HGNC:17496 | Ensembl Gene: ENSG00000165113 | OMIM ID: 611356 |
| Drug and gene relationship at DGIdb | |||
Expression of GKAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GKAP1 | 80318 | 229312_s_at | -0.8736 | 0.2905 | |
| GSE26886 | GKAP1 | 80318 | 229312_s_at | -0.0093 | 0.9664 | |
| GSE45670 | GKAP1 | 80318 | 229312_s_at | -0.6217 | 0.2906 | |
| GSE53622 | GKAP1 | 80318 | 41616 | -0.8306 | 0.0000 | |
| GSE53624 | GKAP1 | 80318 | 41616 | -0.8228 | 0.0000 | |
| GSE63941 | GKAP1 | 80318 | 234192_s_at | 0.8059 | 0.2422 | |
| GSE77861 | GKAP1 | 80318 | 229311_at | -0.0961 | 0.4491 | |
| GSE97050 | GKAP1 | 80318 | A_23_P94546 | -0.6343 | 0.2540 | |
| SRP064894 | GKAP1 | 80318 | RNAseq | -0.3582 | 0.2342 | |
| SRP133303 | GKAP1 | 80318 | RNAseq | -0.6322 | 0.0855 | |
| SRP159526 | GKAP1 | 80318 | RNAseq | -0.1183 | 0.7112 | |
| SRP193095 | GKAP1 | 80318 | RNAseq | -0.2441 | 0.3471 | |
| SRP219564 | GKAP1 | 80318 | RNAseq | -0.8025 | 0.2698 | |
| TCGA | GKAP1 | 80318 | RNAseq | -0.9384 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GKAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GKAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GKAP1 | 80318 | 5 | 10 | 15 | |
| GSE20123 | GKAP1 | 80318 | 5 | 10 | 15 | |
| GSE43470 | GKAP1 | 80318 | 6 | 3 | 34 | |
| GSE46452 | GKAP1 | 80318 | 6 | 14 | 39 | |
| GSE47630 | GKAP1 | 80318 | 1 | 18 | 21 | |
| GSE54993 | GKAP1 | 80318 | 4 | 2 | 64 | |
| GSE54994 | GKAP1 | 80318 | 6 | 12 | 35 | |
| GSE60625 | GKAP1 | 80318 | 0 | 0 | 11 | |
| GSE74703 | GKAP1 | 80318 | 5 | 3 | 28 | |
| GSE74704 | GKAP1 | 80318 | 3 | 7 | 10 | |
| TCGA | GKAP1 | 80318 | 20 | 29 | 47 |
Total number of gains: 61; Total number of losses: 108; Total Number of normals: 319.
Somatic mutations of GKAP1:
Generating mutation plots.
Highly correlated genes for GKAP1:
Showing top 20/295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GKAP1 | SHISA6 | 0.816176 | 3 | 0 | 3 |
| GKAP1 | SLC25A4 | 0.797272 | 4 | 0 | 3 |
| GKAP1 | CBX7 | 0.775394 | 3 | 0 | 3 |
| GKAP1 | MYOM1 | 0.76986 | 4 | 0 | 4 |
| GKAP1 | LDB3 | 0.754446 | 3 | 0 | 3 |
| GKAP1 | ADCY5 | 0.747975 | 4 | 0 | 4 |
| GKAP1 | FENDRR | 0.74425 | 3 | 0 | 3 |
| GKAP1 | LIMS2 | 0.743543 | 3 | 0 | 3 |
| GKAP1 | PRR26 | 0.741327 | 3 | 0 | 3 |
| GKAP1 | HPSE2 | 0.740834 | 3 | 0 | 3 |
| GKAP1 | KBTBD12 | 0.739789 | 4 | 0 | 4 |
| GKAP1 | MOB2 | 0.737747 | 3 | 0 | 3 |
| GKAP1 | GRIN2A | 0.733102 | 3 | 0 | 3 |
| GKAP1 | MYOCD | 0.732136 | 3 | 0 | 3 |
| GKAP1 | RAI2 | 0.731392 | 4 | 0 | 4 |
| GKAP1 | TNS1 | 0.72894 | 3 | 0 | 3 |
| GKAP1 | SYNM | 0.721788 | 3 | 0 | 3 |
| GKAP1 | CALCOCO1 | 0.720784 | 4 | 0 | 3 |
| GKAP1 | DES | 0.719113 | 3 | 0 | 3 |
| GKAP1 | HIF3A | 0.717558 | 4 | 0 | 3 |
For details and further investigation, click here
