SRSF7

 

Full name: serine and arginine rich splicing factor 7 Alias Symbol: 9G8|ZCRB2|HSSG1|AAG3|RBM37|ZCCHC20
Type: protein-coding gene Cytoband: 2p22.1
Entrez ID: 6432 HGNC ID: HGNC:10789 Ensembl Gene: ENSG00000115875 OMIM ID: 600572

 

SRSF7 involved pathways:

KEGG pathway Description View
hsa05168Herpes simplex infection

 

Expression of SRSF7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SRSF7 6432 214141_x_at 0.2525 0.4859
GSE20347 SRSF7 6432 214141_x_at 0.5347 0.0003
GSE23400 SRSF7 6432 214141_x_at 0.5535 0.0000
GSE26886 SRSF7 6432 214141_x_at -0.3849 0.0352
GSE29001 SRSF7 6432 214141_x_at 0.5016 0.1392
GSE38129 SRSF7 6432 214141_x_at 0.5429 0.0000
GSE45670 SRSF7 6432 214141_x_at 0.3952 0.0116
GSE53622 SRSF7 6432 39972 0.3426 0.0000
GSE53624 SRSF7 6432 39972 0.3886 0.0000
GSE63941 SRSF7 6432 214141_x_at 1.5170 0.0000
GSE77861 SRSF7 6432 214141_x_at 0.4838 0.0640
GSE97050 SRSF7 6432 A_33_P3305840 -0.0225 0.9419
SRP007169 SRSF7 6432 RNAseq 0.5536 0.1243
SRP008496 SRSF7 6432 RNAseq 0.6990 0.0013
SRP064894 SRSF7 6432 RNAseq 0.0635 0.6399
SRP133303 SRSF7 6432 RNAseq 0.1609 0.2921
SRP159526 SRSF7 6432 RNAseq 0.2021 0.4861
SRP193095 SRSF7 6432 RNAseq 0.1088 0.2170
SRP219564 SRSF7 6432 RNAseq 0.1258 0.6484

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SRSF7 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of SRSF7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SRSF7 6432 11 1 18
GSE20123 SRSF7 6432 10 1 19
GSE43470 SRSF7 6432 3 0 40
GSE46452 SRSF7 6432 1 4 54
GSE47630 SRSF7 6432 7 0 33
GSE54993 SRSF7 6432 0 5 65
GSE54994 SRSF7 6432 10 0 43
GSE60625 SRSF7 6432 0 3 8
GSE74703 SRSF7 6432 3 0 33
GSE74704 SRSF7 6432 9 1 10
TCGA SRSF7 6432 35 3 58

Total number of gains: 89; Total number of losses: 18; Total Number of normals: 381.  

 

Somatic mutations of SRSF7:

 

Generating mutation plots.

 

Highly correlated genes for SRSF7:

 

Showing top 20/1289 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SRSF7ZFPL10.783763303
SRSF7PIGX0.744949404
SRSF7SRSF30.74006311010
SRSF7CEBPZ0.729322706
SRSF7SFPQ0.722646909
SRSF7M6PR0.719019807
SRSF7SNRPG0.715681908
SRSF7PAIP20.714889303
SRSF7GNB40.714146303
SRSF7ATAD10.711484303
SRSF7ZNF3970.707508303
SRSF7U2SURP0.70607909
SRSF7NASP0.7026941009
SRSF7XPO10.70227111011
SRSF7CCS0.702085403
SRSF7SRSF20.701889303
SRSF7ZNF5670.70188303
SRSF7TADA10.701237303
SRSF7ZSCAN210.699934404
SRSF7NIT10.69831303

For details and further investigation, click here