| Full name: PBX homeobox interacting protein 1 | Alias Symbol: HPIP | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 57326 | HGNC ID: HGNC:21199 | Ensembl Gene: ENSG00000163346 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PBXIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PBXIP1 | 57326 | 214177_s_at | -0.4503 | 0.5786 | |
| GSE20347 | PBXIP1 | 57326 | 214177_s_at | -0.0252 | 0.8829 | |
| GSE23400 | PBXIP1 | 57326 | 214177_s_at | -0.4026 | 0.0000 | |
| GSE26886 | PBXIP1 | 57326 | 214177_s_at | 1.0660 | 0.0000 | |
| GSE29001 | PBXIP1 | 57326 | 214177_s_at | 0.2206 | 0.4333 | |
| GSE38129 | PBXIP1 | 57326 | 214177_s_at | -0.5891 | 0.0450 | |
| GSE45670 | PBXIP1 | 57326 | 214177_s_at | -0.8836 | 0.0000 | |
| GSE53622 | PBXIP1 | 57326 | 119407 | -0.4104 | 0.0004 | |
| GSE53624 | PBXIP1 | 57326 | 119407 | -0.2734 | 0.0020 | |
| GSE63941 | PBXIP1 | 57326 | 214177_s_at | -0.9948 | 0.1426 | |
| GSE77861 | PBXIP1 | 57326 | 212259_s_at | 0.2488 | 0.1719 | |
| GSE97050 | PBXIP1 | 57326 | A_33_P3347413 | -0.7053 | 0.1927 | |
| SRP007169 | PBXIP1 | 57326 | RNAseq | 0.2531 | 0.4948 | |
| SRP008496 | PBXIP1 | 57326 | RNAseq | 0.8262 | 0.0349 | |
| SRP064894 | PBXIP1 | 57326 | RNAseq | -0.2759 | 0.1916 | |
| SRP133303 | PBXIP1 | 57326 | RNAseq | -0.2752 | 0.2778 | |
| SRP159526 | PBXIP1 | 57326 | RNAseq | -0.2314 | 0.2701 | |
| SRP193095 | PBXIP1 | 57326 | RNAseq | 0.2418 | 0.1996 | |
| SRP219564 | PBXIP1 | 57326 | RNAseq | -0.5461 | 0.4875 | |
| TCGA | PBXIP1 | 57326 | RNAseq | -0.5095 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PBXIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PBXIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PBXIP1 | 57326 | 14 | 0 | 16 | |
| GSE20123 | PBXIP1 | 57326 | 13 | 0 | 17 | |
| GSE43470 | PBXIP1 | 57326 | 6 | 2 | 35 | |
| GSE46452 | PBXIP1 | 57326 | 2 | 1 | 56 | |
| GSE47630 | PBXIP1 | 57326 | 14 | 0 | 26 | |
| GSE54993 | PBXIP1 | 57326 | 0 | 4 | 66 | |
| GSE54994 | PBXIP1 | 57326 | 16 | 0 | 37 | |
| GSE60625 | PBXIP1 | 57326 | 0 | 0 | 11 | |
| GSE74703 | PBXIP1 | 57326 | 6 | 1 | 29 | |
| GSE74704 | PBXIP1 | 57326 | 6 | 0 | 14 | |
| TCGA | PBXIP1 | 57326 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of PBXIP1:
Generating mutation plots.
Highly correlated genes for PBXIP1:
Showing top 20/1259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PBXIP1 | KLHL23 | 0.833857 | 3 | 0 | 3 |
| PBXIP1 | MACROD2 | 0.822406 | 3 | 0 | 3 |
| PBXIP1 | TCEAL6 | 0.809101 | 3 | 0 | 3 |
| PBXIP1 | TP53I13 | 0.797648 | 3 | 0 | 3 |
| PBXIP1 | USF2 | 0.79329 | 3 | 0 | 3 |
| PBXIP1 | SSBP4 | 0.785197 | 3 | 0 | 3 |
| PBXIP1 | PARD3B | 0.782441 | 4 | 0 | 4 |
| PBXIP1 | UBXN10 | 0.77291 | 3 | 0 | 3 |
| PBXIP1 | ZNF496 | 0.769374 | 3 | 0 | 3 |
| PBXIP1 | ZNF608 | 0.761752 | 3 | 0 | 3 |
| PBXIP1 | CASQ2 | 0.760226 | 8 | 0 | 8 |
| PBXIP1 | ANO5 | 0.753704 | 5 | 0 | 5 |
| PBXIP1 | GPRASP1 | 0.752587 | 8 | 0 | 7 |
| PBXIP1 | CD99L2 | 0.752367 | 5 | 0 | 5 |
| PBXIP1 | SPIRE1 | 0.751985 | 3 | 0 | 3 |
| PBXIP1 | RILPL1 | 0.746189 | 3 | 0 | 3 |
| PBXIP1 | WDR81 | 0.745296 | 3 | 0 | 3 |
| PBXIP1 | C1QTNF7 | 0.744356 | 5 | 0 | 5 |
| PBXIP1 | HSPB7 | 0.742448 | 8 | 0 | 7 |
| PBXIP1 | MSRB3 | 0.742019 | 5 | 0 | 5 |
For details and further investigation, click here
