| Full name: heat shock protein family B (small) member 7 | Alias Symbol: cvHSP | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 27129 | HGNC ID: HGNC:5249 | Ensembl Gene: ENSG00000173641 | OMIM ID: 610692 |
| Drug and gene relationship at DGIdb | |||
Expression of HSPB7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPB7 | 27129 | 218934_s_at | -1.3499 | 0.4053 | |
| GSE20347 | HSPB7 | 27129 | 218934_s_at | -0.2955 | 0.2027 | |
| GSE23400 | HSPB7 | 27129 | 218934_s_at | -0.4132 | 0.0270 | |
| GSE26886 | HSPB7 | 27129 | 218934_s_at | 0.1261 | 0.3245 | |
| GSE29001 | HSPB7 | 27129 | 218934_s_at | -0.2323 | 0.1538 | |
| GSE38129 | HSPB7 | 27129 | 218934_s_at | -1.2354 | 0.0104 | |
| GSE45670 | HSPB7 | 27129 | 218934_s_at | -1.0440 | 0.0000 | |
| GSE53622 | HSPB7 | 27129 | 24036 | -1.9515 | 0.0000 | |
| GSE53624 | HSPB7 | 27129 | 24036 | -1.5320 | 0.0000 | |
| GSE63941 | HSPB7 | 27129 | 218934_s_at | -0.2475 | 0.1681 | |
| GSE77861 | HSPB7 | 27129 | 218934_s_at | 0.0169 | 0.8816 | |
| GSE97050 | HSPB7 | 27129 | A_23_P103703 | -1.4092 | 0.1204 | |
| SRP064894 | HSPB7 | 27129 | RNAseq | 0.2947 | 0.5743 | |
| SRP133303 | HSPB7 | 27129 | RNAseq | -2.4894 | 0.0000 | |
| SRP219564 | HSPB7 | 27129 | RNAseq | -0.2348 | 0.8656 | |
| TCGA | HSPB7 | 27129 | RNAseq | -1.2447 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by HSPB7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPB7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPB7 | 27129 | 1 | 5 | 24 | |
| GSE20123 | HSPB7 | 27129 | 1 | 4 | 25 | |
| GSE43470 | HSPB7 | 27129 | 1 | 8 | 34 | |
| GSE46452 | HSPB7 | 27129 | 7 | 1 | 51 | |
| GSE47630 | HSPB7 | 27129 | 8 | 3 | 29 | |
| GSE54993 | HSPB7 | 27129 | 3 | 1 | 66 | |
| GSE54994 | HSPB7 | 27129 | 10 | 4 | 39 | |
| GSE60625 | HSPB7 | 27129 | 0 | 0 | 11 | |
| GSE74703 | HSPB7 | 27129 | 1 | 5 | 30 | |
| GSE74704 | HSPB7 | 27129 | 1 | 0 | 19 | |
| TCGA | HSPB7 | 27129 | 12 | 23 | 61 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of HSPB7:
Generating mutation plots.
Highly correlated genes for HSPB7:
Showing top 20/1154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPB7 | UBXN10 | 0.892914 | 3 | 0 | 3 |
| HSPB7 | PYGM | 0.826642 | 9 | 0 | 9 |
| HSPB7 | PPP1R12B | 0.823623 | 9 | 0 | 8 |
| HSPB7 | NCAM1 | 0.817602 | 8 | 0 | 8 |
| HSPB7 | SGCA | 0.814773 | 11 | 0 | 11 |
| HSPB7 | TNFSF12 | 0.811106 | 3 | 0 | 3 |
| HSPB7 | ITGA7 | 0.81015 | 10 | 0 | 10 |
| HSPB7 | FILIP1 | 0.810122 | 5 | 0 | 5 |
| HSPB7 | PDZRN4 | 0.798409 | 10 | 0 | 10 |
| HSPB7 | CDH19 | 0.797764 | 9 | 0 | 9 |
| HSPB7 | SLMAP | 0.794279 | 5 | 0 | 5 |
| HSPB7 | MYADM | 0.792199 | 3 | 0 | 3 |
| HSPB7 | CLEC3B | 0.791804 | 3 | 0 | 3 |
| HSPB7 | CTNNA3 | 0.791426 | 6 | 0 | 5 |
| HSPB7 | SMOC2 | 0.788713 | 5 | 0 | 5 |
| HSPB7 | PPP1R12A | 0.78727 | 8 | 0 | 8 |
| HSPB7 | FENDRR | 0.786697 | 5 | 0 | 5 |
| HSPB7 | MRVI1 | 0.784198 | 8 | 0 | 8 |
| HSPB7 | SYNM | 0.783957 | 10 | 0 | 10 |
| HSPB7 | LMOD1 | 0.780819 | 12 | 0 | 12 |
For details and further investigation, click here
