| Full name: mono-ADP ribosylhydrolase 2 | Alias Symbol: dJ631M13.5 | ||
| Type: protein-coding gene | Cytoband: 20p12.1 | ||
| Entrez ID: 140733 | HGNC ID: HGNC:16126 | Ensembl Gene: ENSG00000172264 | OMIM ID: 611567 |
| Drug and gene relationship at DGIdb | |||
Expression of MACROD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MACROD2 | 140733 | 235278_at | -0.6306 | 0.3490 | |
| GSE26886 | MACROD2 | 140733 | 235278_at | -0.1609 | 0.7735 | |
| GSE45670 | MACROD2 | 140733 | 235278_at | -1.0936 | 0.0001 | |
| GSE53622 | MACROD2 | 140733 | 36186 | 0.1506 | 0.0633 | |
| GSE53624 | MACROD2 | 140733 | 36186 | -0.0529 | 0.3780 | |
| GSE63941 | MACROD2 | 140733 | 235278_at | -0.5943 | 0.1988 | |
| GSE77861 | MACROD2 | 140733 | 235278_at | -0.3188 | 0.0903 | |
| GSE97050 | MACROD2 | 140733 | A_33_P3281033 | -0.2358 | 0.3450 | |
| SRP064894 | MACROD2 | 140733 | RNAseq | -0.6873 | 0.0183 | |
| SRP133303 | MACROD2 | 140733 | RNAseq | -1.4813 | 0.0000 | |
| SRP159526 | MACROD2 | 140733 | RNAseq | -0.8778 | 0.0435 | |
| SRP193095 | MACROD2 | 140733 | RNAseq | -0.5026 | 0.1392 | |
| SRP219564 | MACROD2 | 140733 | RNAseq | -0.4103 | 0.5980 | |
| TCGA | MACROD2 | 140733 | RNAseq | -1.2714 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by MACROD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MACROD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MACROD2 | 140733 | 10 | 2 | 18 | |
| GSE20123 | MACROD2 | 140733 | 10 | 2 | 18 | |
| GSE43470 | MACROD2 | 140733 | 11 | 2 | 30 | |
| GSE46452 | MACROD2 | 140733 | 26 | 1 | 32 | |
| GSE47630 | MACROD2 | 140733 | 17 | 6 | 17 | |
| GSE54993 | MACROD2 | 140733 | 0 | 16 | 54 | |
| GSE54994 | MACROD2 | 140733 | 24 | 3 | 26 | |
| GSE60625 | MACROD2 | 140733 | 0 | 0 | 11 | |
| GSE74703 | MACROD2 | 140733 | 8 | 2 | 26 | |
| GSE74704 | MACROD2 | 140733 | 5 | 2 | 13 | |
| TCGA | MACROD2 | 140733 | 44 | 12 | 40 |
Total number of gains: 155; Total number of losses: 48; Total Number of normals: 285.
Somatic mutations of MACROD2:
Generating mutation plots.
Highly correlated genes for MACROD2:
Showing top 20/543 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MACROD2 | ZMYND11 | 0.857643 | 3 | 0 | 3 |
| MACROD2 | KLHL15 | 0.838878 | 3 | 0 | 3 |
| MACROD2 | C7 | 0.832761 | 3 | 0 | 3 |
| MACROD2 | TXNIP | 0.830898 | 3 | 0 | 3 |
| MACROD2 | PBXIP1 | 0.822406 | 3 | 0 | 3 |
| MACROD2 | ITGA9 | 0.820651 | 3 | 0 | 3 |
| MACROD2 | AFF3 | 0.815867 | 3 | 0 | 3 |
| MACROD2 | POLR3GL | 0.806051 | 3 | 0 | 3 |
| MACROD2 | SAMHD1 | 0.805653 | 3 | 0 | 3 |
| MACROD2 | FRAS1 | 0.798623 | 3 | 0 | 3 |
| MACROD2 | PFDN5 | 0.784612 | 3 | 0 | 3 |
| MACROD2 | MYOCD | 0.782609 | 3 | 0 | 3 |
| MACROD2 | ZRANB2 | 0.778051 | 3 | 0 | 3 |
| MACROD2 | ZNF512 | 0.774377 | 3 | 0 | 3 |
| MACROD2 | STK38L | 0.77282 | 3 | 0 | 3 |
| MACROD2 | PPP1R12B | 0.772252 | 3 | 0 | 3 |
| MACROD2 | FBXL17 | 0.769194 | 3 | 0 | 3 |
| MACROD2 | CBX7 | 0.76761 | 3 | 0 | 3 |
| MACROD2 | APOD | 0.76595 | 3 | 0 | 3 |
| MACROD2 | DTNA | 0.765816 | 3 | 0 | 3 |
For details and further investigation, click here
