| Full name: upstream transcription factor 2, c-fos interacting | Alias Symbol: FIP|bHLHb12 | ||
| Type: protein-coding gene | Cytoband: 19q13 | ||
| Entrez ID: 7392 | HGNC ID: HGNC:12594 | Ensembl Gene: ENSG00000105698 | OMIM ID: 600390 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of USF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USF2 | 7392 | 202152_x_at | 0.3113 | 0.3731 | |
| GSE20347 | USF2 | 7392 | 202152_x_at | 0.0788 | 0.5891 | |
| GSE23400 | USF2 | 7392 | 202152_x_at | 0.0712 | 0.0976 | |
| GSE26886 | USF2 | 7392 | 215737_x_at | 0.1495 | 0.3209 | |
| GSE29001 | USF2 | 7392 | 215737_x_at | 0.1848 | 0.5888 | |
| GSE38129 | USF2 | 7392 | 202152_x_at | -0.0090 | 0.9339 | |
| GSE45670 | USF2 | 7392 | 215737_x_at | 0.0739 | 0.3981 | |
| GSE53622 | USF2 | 7392 | 51335 | 0.0606 | 0.3106 | |
| GSE53624 | USF2 | 7392 | 140547 | -0.0301 | 0.5469 | |
| GSE63941 | USF2 | 7392 | 202152_x_at | 0.6397 | 0.0165 | |
| GSE77861 | USF2 | 7392 | 202152_x_at | 0.2219 | 0.1924 | |
| GSE97050 | USF2 | 7392 | A_33_P3299982 | -0.2903 | 0.3427 | |
| SRP007169 | USF2 | 7392 | RNAseq | -0.7930 | 0.0175 | |
| SRP008496 | USF2 | 7392 | RNAseq | -1.1069 | 0.0000 | |
| SRP064894 | USF2 | 7392 | RNAseq | 0.6363 | 0.0130 | |
| SRP133303 | USF2 | 7392 | RNAseq | 0.0123 | 0.9447 | |
| SRP159526 | USF2 | 7392 | RNAseq | 0.5402 | 0.0010 | |
| SRP193095 | USF2 | 7392 | RNAseq | 0.2711 | 0.0313 | |
| SRP219564 | USF2 | 7392 | RNAseq | -0.2370 | 0.3999 | |
| TCGA | USF2 | 7392 | RNAseq | 0.0565 | 0.2223 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by USF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USF2 | 7392 | 6 | 4 | 20 | |
| GSE20123 | USF2 | 7392 | 6 | 3 | 21 | |
| GSE43470 | USF2 | 7392 | 3 | 7 | 33 | |
| GSE46452 | USF2 | 7392 | 48 | 1 | 10 | |
| GSE47630 | USF2 | 7392 | 9 | 5 | 26 | |
| GSE54993 | USF2 | 7392 | 17 | 3 | 50 | |
| GSE54994 | USF2 | 7392 | 8 | 9 | 36 | |
| GSE60625 | USF2 | 7392 | 9 | 0 | 2 | |
| GSE74703 | USF2 | 7392 | 3 | 4 | 29 | |
| GSE74704 | USF2 | 7392 | 6 | 1 | 13 | |
| TCGA | USF2 | 7392 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of USF2:
Generating mutation plots.
Highly correlated genes for USF2:
Showing top 20/584 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USF2 | CYHR1 | 0.833855 | 3 | 0 | 3 |
| USF2 | FOXP4 | 0.81823 | 3 | 0 | 3 |
| USF2 | ULK1 | 0.810791 | 3 | 0 | 3 |
| USF2 | PBXIP1 | 0.79329 | 3 | 0 | 3 |
| USF2 | SSBP4 | 0.760586 | 4 | 0 | 3 |
| USF2 | SURF6 | 0.746165 | 3 | 0 | 3 |
| USF2 | ZNF496 | 0.738976 | 3 | 0 | 3 |
| USF2 | INPP5E | 0.738249 | 4 | 0 | 4 |
| USF2 | UBE2O | 0.735895 | 4 | 0 | 3 |
| USF2 | RBM4B | 0.730043 | 3 | 0 | 3 |
| USF2 | BTN3A1 | 0.716099 | 3 | 0 | 3 |
| USF2 | FAM3A | 0.711511 | 3 | 0 | 3 |
| USF2 | B4GALT2 | 0.710337 | 4 | 0 | 4 |
| USF2 | ASPSCR1 | 0.710036 | 4 | 0 | 4 |
| USF2 | MIA3 | 0.708988 | 3 | 0 | 3 |
| USF2 | TPRA1 | 0.707913 | 3 | 0 | 3 |
| USF2 | RAB7A | 0.705933 | 3 | 0 | 3 |
| USF2 | TMTC4 | 0.702565 | 3 | 0 | 3 |
| USF2 | KDM4A | 0.702208 | 4 | 0 | 3 |
| USF2 | ARHGEF2 | 0.701747 | 4 | 0 | 4 |
For details and further investigation, click here
