| Full name: par-3 family cell polarity regulator beta | Alias Symbol: Par3L|PAR3beta | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 117583 | HGNC ID: HGNC:14446 | Ensembl Gene: ENSG00000116117 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PARD3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARD3B | 117583 | 228411_at | -1.0543 | 0.1731 | |
| GSE26886 | PARD3B | 117583 | 1553190_s_at | -0.0043 | 0.9778 | |
| GSE45670 | PARD3B | 117583 | 1553190_s_at | 0.0385 | 0.7174 | |
| GSE53622 | PARD3B | 117583 | 131786 | -1.0800 | 0.0000 | |
| GSE53624 | PARD3B | 117583 | 131786 | -0.9874 | 0.0000 | |
| GSE63941 | PARD3B | 117583 | 228411_at | -3.2668 | 0.0001 | |
| GSE77861 | PARD3B | 117583 | 1553190_s_at | -0.1996 | 0.0974 | |
| GSE97050 | PARD3B | 117583 | A_24_P34534 | -0.9714 | 0.1057 | |
| SRP007169 | PARD3B | 117583 | RNAseq | 0.2089 | 0.7276 | |
| SRP064894 | PARD3B | 117583 | RNAseq | -0.5681 | 0.0694 | |
| SRP133303 | PARD3B | 117583 | RNAseq | -0.6104 | 0.0670 | |
| SRP159526 | PARD3B | 117583 | RNAseq | -0.1292 | 0.7603 | |
| SRP193095 | PARD3B | 117583 | RNAseq | -0.6407 | 0.0221 | |
| SRP219564 | PARD3B | 117583 | RNAseq | -0.4228 | 0.5924 | |
| TCGA | PARD3B | 117583 | RNAseq | -1.2061 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PARD3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARD3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARD3B | 117583 | 5 | 5 | 20 | |
| GSE20123 | PARD3B | 117583 | 5 | 5 | 20 | |
| GSE43470 | PARD3B | 117583 | 1 | 4 | 38 | |
| GSE46452 | PARD3B | 117583 | 1 | 4 | 54 | |
| GSE47630 | PARD3B | 117583 | 4 | 5 | 31 | |
| GSE54993 | PARD3B | 117583 | 0 | 3 | 67 | |
| GSE54994 | PARD3B | 117583 | 9 | 10 | 34 | |
| GSE60625 | PARD3B | 117583 | 0 | 3 | 8 | |
| GSE74703 | PARD3B | 117583 | 1 | 3 | 32 | |
| GSE74704 | PARD3B | 117583 | 3 | 2 | 15 | |
| TCGA | PARD3B | 117583 | 17 | 20 | 59 |
Total number of gains: 46; Total number of losses: 64; Total Number of normals: 378.
Somatic mutations of PARD3B:
Generating mutation plots.
Highly correlated genes for PARD3B:
Showing top 20/893 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARD3B | SYNC | 0.877324 | 3 | 0 | 3 |
| PARD3B | CBX7 | 0.863943 | 4 | 0 | 4 |
| PARD3B | BHMT2 | 0.856303 | 5 | 0 | 5 |
| PARD3B | XKR4 | 0.849367 | 4 | 0 | 4 |
| PARD3B | MYOCD | 0.837966 | 5 | 0 | 5 |
| PARD3B | SORCS1 | 0.82925 | 4 | 0 | 4 |
| PARD3B | FOXN3 | 0.824255 | 3 | 0 | 3 |
| PARD3B | SLITRK3 | 0.808524 | 4 | 0 | 4 |
| PARD3B | ANO5 | 0.807669 | 5 | 0 | 5 |
| PARD3B | PGR | 0.806267 | 4 | 0 | 4 |
| PARD3B | APOD | 0.806215 | 4 | 0 | 4 |
| PARD3B | MAOB | 0.804633 | 4 | 0 | 4 |
| PARD3B | PRUNE2 | 0.802941 | 5 | 0 | 5 |
| PARD3B | ABCA6 | 0.801567 | 5 | 0 | 5 |
| PARD3B | MAN1C1 | 0.798149 | 5 | 0 | 5 |
| PARD3B | RYR3 | 0.793934 | 3 | 0 | 3 |
| PARD3B | SPATA6 | 0.793478 | 4 | 0 | 4 |
| PARD3B | BCHE | 0.792822 | 4 | 0 | 4 |
| PARD3B | EIF4E3 | 0.791421 | 5 | 0 | 5 |
| PARD3B | RASL12 | 0.790688 | 5 | 0 | 5 |
For details and further investigation, click here
