| Full name: kelch like family member 23 | Alias Symbol: MGC2610|FLJ37812|MGC22679 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 151230 | HGNC ID: HGNC:27506 | Ensembl Gene: ENSG00000213160 | OMIM ID: |
Expression of KLHL23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL23 | 151230 | 241682_at | -0.3474 | 0.7751 | |
| GSE26886 | KLHL23 | 151230 | 241682_at | 0.1994 | 0.4651 | |
| GSE45670 | KLHL23 | 151230 | 241682_at | -0.5795 | 0.0260 | |
| GSE53622 | KLHL23 | 151230 | 39311 | -0.4093 | 0.0201 | |
| GSE53624 | KLHL23 | 151230 | 39311 | 0.1211 | 0.3188 | |
| GSE63941 | KLHL23 | 151230 | 241682_at | 1.3843 | 0.0232 | |
| GSE77861 | KLHL23 | 151230 | 241682_at | 0.2219 | 0.1722 | |
| GSE97050 | KLHL23 | 151230 | A_23_P165414 | -0.2696 | 0.3161 | |
| SRP007169 | KLHL23 | 151230 | RNAseq | 3.8744 | 0.0001 | |
| SRP064894 | KLHL23 | 151230 | RNAseq | -0.7132 | 0.1679 | |
| SRP133303 | KLHL23 | 151230 | RNAseq | -0.0493 | 0.8853 | |
| SRP159526 | KLHL23 | 151230 | RNAseq | 0.2116 | 0.6198 | |
| SRP219564 | KLHL23 | 151230 | RNAseq | -0.6732 | 0.4088 | |
| TCGA | KLHL23 | 151230 | RNAseq | -0.2325 | 0.2077 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KLHL23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL23 | 151230 | 7 | 0 | 23 | |
| GSE20123 | KLHL23 | 151230 | 7 | 0 | 23 | |
| GSE43470 | KLHL23 | 151230 | 4 | 1 | 38 | |
| GSE46452 | KLHL23 | 151230 | 1 | 4 | 54 | |
| GSE47630 | KLHL23 | 151230 | 5 | 3 | 32 | |
| GSE54993 | KLHL23 | 151230 | 0 | 5 | 65 | |
| GSE54994 | KLHL23 | 151230 | 11 | 3 | 39 | |
| GSE60625 | KLHL23 | 151230 | 0 | 3 | 8 | |
| GSE74703 | KLHL23 | 151230 | 3 | 1 | 32 | |
| GSE74704 | KLHL23 | 151230 | 4 | 0 | 16 | |
| TCGA | KLHL23 | 151230 | 24 | 10 | 62 |
Total number of gains: 66; Total number of losses: 30; Total Number of normals: 392.
Somatic mutations of KLHL23:
Generating mutation plots.
Highly correlated genes for KLHL23:
Showing top 20/305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL23 | PBXIP1 | 0.833857 | 3 | 0 | 3 |
| KLHL23 | MYEF2 | 0.829148 | 3 | 0 | 3 |
| KLHL23 | ESRRG | 0.761509 | 3 | 0 | 3 |
| KLHL23 | RNF115 | 0.757915 | 3 | 0 | 3 |
| KLHL23 | PYGM | 0.755922 | 3 | 0 | 3 |
| KLHL23 | SLC2A12 | 0.753862 | 3 | 0 | 3 |
| KLHL23 | TSPYL2 | 0.75306 | 3 | 0 | 3 |
| KLHL23 | KIAA0753 | 0.74847 | 3 | 0 | 3 |
| KLHL23 | MOAP1 | 0.745611 | 4 | 0 | 4 |
| KLHL23 | RGS9 | 0.745117 | 3 | 0 | 3 |
| KLHL23 | PIK3R1 | 0.742601 | 3 | 0 | 3 |
| KLHL23 | STK38L | 0.73833 | 4 | 0 | 4 |
| KLHL23 | PSIP1 | 0.730884 | 5 | 0 | 4 |
| KLHL23 | SORL1 | 0.72288 | 3 | 0 | 3 |
| KLHL23 | PRELP | 0.713474 | 3 | 0 | 3 |
| KLHL23 | APLP2 | 0.7132 | 4 | 0 | 3 |
| KLHL23 | TACC2 | 0.710485 | 3 | 0 | 3 |
| KLHL23 | SLC26A10 | 0.708274 | 3 | 0 | 3 |
| KLHL23 | UGGT2 | 0.706913 | 3 | 0 | 3 |
| KLHL23 | ZER1 | 0.705216 | 3 | 0 | 3 |
For details and further investigation, click here
