| Full name: peroxisomal biogenesis factor 7 | Alias Symbol: PTS2R|RD | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 5191 | HGNC ID: HGNC:8860 | Ensembl Gene: ENSG00000112357 | OMIM ID: 601757 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX7 | 5191 | 211033_s_at | -0.1937 | 0.7240 | |
| GSE20347 | PEX7 | 5191 | 211033_s_at | -0.3726 | 0.0059 | |
| GSE23400 | PEX7 | 5191 | 211033_s_at | -0.1790 | 0.0020 | |
| GSE26886 | PEX7 | 5191 | 211033_s_at | -0.7929 | 0.0010 | |
| GSE29001 | PEX7 | 5191 | 211033_s_at | -0.1869 | 0.5323 | |
| GSE38129 | PEX7 | 5191 | 211033_s_at | -0.2017 | 0.1501 | |
| GSE45670 | PEX7 | 5191 | 205420_at | -0.3634 | 0.0671 | |
| GSE53622 | PEX7 | 5191 | 49663 | -0.3096 | 0.0002 | |
| GSE53624 | PEX7 | 5191 | 49663 | -0.3532 | 0.0000 | |
| GSE63941 | PEX7 | 5191 | 211033_s_at | -0.2807 | 0.5323 | |
| GSE77861 | PEX7 | 5191 | 211033_s_at | -0.2050 | 0.2928 | |
| GSE97050 | PEX7 | 5191 | A_33_P3412095 | -0.0907 | 0.7619 | |
| SRP007169 | PEX7 | 5191 | RNAseq | -0.8048 | 0.0289 | |
| SRP008496 | PEX7 | 5191 | RNAseq | -0.5504 | 0.0319 | |
| SRP064894 | PEX7 | 5191 | RNAseq | -0.3736 | 0.0448 | |
| SRP133303 | PEX7 | 5191 | RNAseq | -0.2670 | 0.0383 | |
| SRP159526 | PEX7 | 5191 | RNAseq | -0.3552 | 0.2080 | |
| SRP193095 | PEX7 | 5191 | RNAseq | -0.8568 | 0.0000 | |
| SRP219564 | PEX7 | 5191 | RNAseq | -0.4987 | 0.0677 | |
| TCGA | PEX7 | 5191 | RNAseq | -0.4505 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX7 | 5191 | 4 | 4 | 22 | |
| GSE20123 | PEX7 | 5191 | 3 | 3 | 24 | |
| GSE43470 | PEX7 | 5191 | 5 | 0 | 38 | |
| GSE46452 | PEX7 | 5191 | 3 | 10 | 46 | |
| GSE47630 | PEX7 | 5191 | 9 | 4 | 27 | |
| GSE54993 | PEX7 | 5191 | 3 | 2 | 65 | |
| GSE54994 | PEX7 | 5191 | 9 | 7 | 37 | |
| GSE60625 | PEX7 | 5191 | 0 | 1 | 10 | |
| GSE74703 | PEX7 | 5191 | 4 | 0 | 32 | |
| GSE74704 | PEX7 | 5191 | 1 | 1 | 18 | |
| TCGA | PEX7 | 5191 | 12 | 17 | 67 |
Total number of gains: 53; Total number of losses: 49; Total Number of normals: 386.
Somatic mutations of PEX7:
Generating mutation plots.
Highly correlated genes for PEX7:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX7 | MOB1B | 0.726121 | 3 | 0 | 3 |
| PEX7 | TRAPPC13 | 0.690604 | 3 | 0 | 3 |
| PEX7 | NT5C1A | 0.675375 | 3 | 0 | 3 |
| PEX7 | WDR44 | 0.652374 | 3 | 0 | 3 |
| PEX7 | RAB11FIP4 | 0.6451 | 4 | 0 | 3 |
| PEX7 | MAST4 | 0.639024 | 3 | 0 | 3 |
| PEX7 | RNF215 | 0.638068 | 3 | 0 | 3 |
| PEX7 | ZNF675 | 0.621743 | 3 | 0 | 3 |
| PEX7 | PCP2 | 0.616456 | 3 | 0 | 3 |
| PEX7 | TRAPPC11 | 0.611388 | 4 | 0 | 4 |
| PEX7 | TMEM125 | 0.610703 | 5 | 0 | 4 |
| PEX7 | SNX21 | 0.603484 | 4 | 0 | 3 |
| PEX7 | ERBB3 | 0.600219 | 4 | 0 | 3 |
| PEX7 | C4orf33 | 0.595657 | 4 | 0 | 3 |
| PEX7 | RTKN2 | 0.595175 | 3 | 0 | 3 |
| PEX7 | PAOX | 0.593006 | 4 | 0 | 3 |
| PEX7 | YIPF1 | 0.591183 | 7 | 0 | 4 |
| PEX7 | RPIA | 0.586831 | 5 | 0 | 3 |
| PEX7 | COQ5 | 0.582655 | 5 | 0 | 3 |
| PEX7 | BCL2L13 | 0.579481 | 3 | 0 | 3 |
For details and further investigation, click here
