| Full name: ribose 5-phosphate isomerase A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 22934 | HGNC ID: HGNC:10297 | Ensembl Gene: ENSG00000153574 | OMIM ID: 180430 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPIA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPIA | 22934 | 212973_at | 0.1698 | 0.7031 | |
| GSE20347 | RPIA | 22934 | 212973_at | -0.3077 | 0.0763 | |
| GSE23400 | RPIA | 22934 | 212973_at | -0.1251 | 0.1381 | |
| GSE26886 | RPIA | 22934 | 212973_at | -1.0637 | 0.0000 | |
| GSE29001 | RPIA | 22934 | 212973_at | -0.2747 | 0.2928 | |
| GSE38129 | RPIA | 22934 | 212973_at | -0.1075 | 0.5104 | |
| GSE45670 | RPIA | 22934 | 212973_at | -0.2219 | 0.2748 | |
| GSE53622 | RPIA | 22934 | 7721 | -0.1532 | 0.0982 | |
| GSE53624 | RPIA | 22934 | 7721 | -0.4167 | 0.0000 | |
| GSE63941 | RPIA | 22934 | 212973_at | 0.4463 | 0.4279 | |
| GSE77861 | RPIA | 22934 | 212973_at | -0.3286 | 0.1041 | |
| GSE97050 | RPIA | 22934 | A_23_P131646 | 0.0378 | 0.9297 | |
| SRP007169 | RPIA | 22934 | RNAseq | -1.1381 | 0.0056 | |
| SRP008496 | RPIA | 22934 | RNAseq | -1.0819 | 0.0000 | |
| SRP064894 | RPIA | 22934 | RNAseq | -0.6849 | 0.0001 | |
| SRP133303 | RPIA | 22934 | RNAseq | -0.6175 | 0.0018 | |
| SRP159526 | RPIA | 22934 | RNAseq | 0.3494 | 0.1573 | |
| SRP193095 | RPIA | 22934 | RNAseq | -0.7772 | 0.0000 | |
| SRP219564 | RPIA | 22934 | RNAseq | -0.1787 | 0.7302 | |
| TCGA | RPIA | 22934 | RNAseq | 0.0510 | 0.4522 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPIA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPIA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPIA | 22934 | 9 | 3 | 18 | |
| GSE20123 | RPIA | 22934 | 9 | 3 | 18 | |
| GSE43470 | RPIA | 22934 | 2 | 2 | 39 | |
| GSE46452 | RPIA | 22934 | 2 | 3 | 54 | |
| GSE47630 | RPIA | 22934 | 7 | 0 | 33 | |
| GSE54993 | RPIA | 22934 | 0 | 6 | 64 | |
| GSE54994 | RPIA | 22934 | 10 | 0 | 43 | |
| GSE60625 | RPIA | 22934 | 0 | 3 | 8 | |
| GSE74703 | RPIA | 22934 | 2 | 1 | 33 | |
| GSE74704 | RPIA | 22934 | 7 | 0 | 13 | |
| TCGA | RPIA | 22934 | 34 | 4 | 58 |
Total number of gains: 82; Total number of losses: 25; Total Number of normals: 381.
Somatic mutations of RPIA:
Generating mutation plots.
Highly correlated genes for RPIA:
Showing top 20/122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPIA | FANK1 | 0.813646 | 3 | 0 | 3 |
| RPIA | PTK6 | 0.745824 | 3 | 0 | 3 |
| RPIA | SH2D1B | 0.742703 | 3 | 0 | 3 |
| RPIA | RDH13 | 0.722824 | 3 | 0 | 3 |
| RPIA | AKR7A3 | 0.71785 | 3 | 0 | 3 |
| RPIA | SLC23A3 | 0.716264 | 3 | 0 | 3 |
| RPIA | CEP135 | 0.707142 | 3 | 0 | 3 |
| RPIA | B3GNT8 | 0.706405 | 3 | 0 | 3 |
| RPIA | RUSC1 | 0.689239 | 3 | 0 | 3 |
| RPIA | MATK | 0.676393 | 3 | 0 | 3 |
| RPIA | ZNF365 | 0.657134 | 3 | 0 | 3 |
| RPIA | TMEM125 | 0.654477 | 4 | 0 | 3 |
| RPIA | TMEM217 | 0.654218 | 4 | 0 | 3 |
| RPIA | PHYHIP | 0.650296 | 4 | 0 | 3 |
| RPIA | DIO2 | 0.641129 | 4 | 0 | 3 |
| RPIA | MAFG | 0.631162 | 4 | 0 | 3 |
| RPIA | PCYT2 | 0.621858 | 3 | 0 | 3 |
| RPIA | TLCD2 | 0.617563 | 3 | 0 | 3 |
| RPIA | GGT6 | 0.614734 | 5 | 0 | 3 |
| RPIA | GALR3 | 0.614451 | 4 | 0 | 3 |
For details and further investigation, click here
