| Full name: rhotekin 2 | Alias Symbol: Em:AC024597.2|bA531F24.1|FLJ39352 | ||
| Type: protein-coding gene | Cytoband: 10q21.2 | ||
| Entrez ID: 219790 | HGNC ID: HGNC:19364 | Ensembl Gene: ENSG00000182010 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RTKN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTKN2 | 219790 | 242047_at | -0.0989 | 0.7175 | |
| GSE26886 | RTKN2 | 219790 | 230469_at | -0.6802 | 0.0008 | |
| GSE45670 | RTKN2 | 219790 | 230469_at | 0.0184 | 0.9672 | |
| GSE53622 | RTKN2 | 219790 | 1162 | -0.2831 | 0.2471 | |
| GSE53624 | RTKN2 | 219790 | 1162 | -0.6732 | 0.0000 | |
| GSE63941 | RTKN2 | 219790 | 242047_at | 0.1074 | 0.6330 | |
| GSE77861 | RTKN2 | 219790 | 242047_at | -0.3258 | 0.0076 | |
| GSE97050 | RTKN2 | 219790 | A_33_P3219527 | 0.0873 | 0.7674 | |
| SRP007169 | RTKN2 | 219790 | RNAseq | -2.9659 | 0.0000 | |
| SRP008496 | RTKN2 | 219790 | RNAseq | -2.7257 | 0.0000 | |
| SRP064894 | RTKN2 | 219790 | RNAseq | -2.1086 | 0.0000 | |
| SRP133303 | RTKN2 | 219790 | RNAseq | -1.1171 | 0.0001 | |
| SRP159526 | RTKN2 | 219790 | RNAseq | -2.1674 | 0.0000 | |
| SRP193095 | RTKN2 | 219790 | RNAseq | -1.9718 | 0.0000 | |
| SRP219564 | RTKN2 | 219790 | RNAseq | -2.2439 | 0.0183 | |
| TCGA | RTKN2 | 219790 | RNAseq | 0.5985 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by RTKN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTKN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTKN2 | 219790 | 2 | 7 | 21 | |
| GSE20123 | RTKN2 | 219790 | 2 | 7 | 21 | |
| GSE43470 | RTKN2 | 219790 | 2 | 5 | 36 | |
| GSE46452 | RTKN2 | 219790 | 0 | 11 | 48 | |
| GSE47630 | RTKN2 | 219790 | 4 | 12 | 24 | |
| GSE54993 | RTKN2 | 219790 | 9 | 0 | 61 | |
| GSE54994 | RTKN2 | 219790 | 3 | 9 | 41 | |
| GSE60625 | RTKN2 | 219790 | 0 | 0 | 11 | |
| GSE74703 | RTKN2 | 219790 | 2 | 3 | 31 | |
| GSE74704 | RTKN2 | 219790 | 1 | 5 | 14 | |
| TCGA | RTKN2 | 219790 | 11 | 23 | 62 |
Total number of gains: 36; Total number of losses: 82; Total Number of normals: 370.
Somatic mutations of RTKN2:
Generating mutation plots.
Highly correlated genes for RTKN2:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTKN2 | SNX16 | 0.770493 | 3 | 0 | 3 |
| RTKN2 | STXBP2 | 0.720602 | 3 | 0 | 3 |
| RTKN2 | ESPL1 | 0.711454 | 6 | 0 | 5 |
| RTKN2 | ACPP | 0.699111 | 5 | 0 | 5 |
| RTKN2 | ZNF780A | 0.697918 | 3 | 0 | 3 |
| RTKN2 | MACC1 | 0.695334 | 6 | 0 | 5 |
| RTKN2 | SHQ1 | 0.683982 | 3 | 0 | 3 |
| RTKN2 | SPNS2 | 0.683417 | 3 | 0 | 3 |
| RTKN2 | PDZRN3 | 0.672727 | 3 | 0 | 3 |
| RTKN2 | EBP | 0.6724 | 4 | 0 | 3 |
| RTKN2 | MAPK13 | 0.668107 | 5 | 0 | 5 |
| RTKN2 | ABCD3 | 0.665901 | 5 | 0 | 4 |
| RTKN2 | ADAMTS17 | 0.665519 | 4 | 0 | 4 |
| RTKN2 | ULBP2 | 0.665275 | 3 | 0 | 3 |
| RTKN2 | WWC1 | 0.664761 | 4 | 0 | 4 |
| RTKN2 | ANKRD22 | 0.660219 | 3 | 0 | 3 |
| RTKN2 | EREG | 0.659828 | 3 | 0 | 3 |
| RTKN2 | STK24 | 0.658932 | 5 | 0 | 4 |
| RTKN2 | UBN2 | 0.657916 | 3 | 0 | 3 |
| RTKN2 | HCAR3 | 0.655792 | 5 | 0 | 4 |
For details and further investigation, click here
