| Full name: coenzyme Q5, methyltransferase | Alias Symbol: MGC4767 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 84274 | HGNC ID: HGNC:28722 | Ensembl Gene: ENSG00000110871 | OMIM ID: 616359 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COQ5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ5 | 84274 | 223114_at | 0.0113 | 0.9829 | |
| GSE26886 | COQ5 | 84274 | 223114_at | -0.2658 | 0.2936 | |
| GSE45670 | COQ5 | 84274 | 223114_at | 0.1930 | 0.0685 | |
| GSE53622 | COQ5 | 84274 | 37509 | 0.1916 | 0.0067 | |
| GSE53624 | COQ5 | 84274 | 37509 | 0.2742 | 0.0002 | |
| GSE63941 | COQ5 | 84274 | 223114_at | -0.0280 | 0.9541 | |
| GSE77861 | COQ5 | 84274 | 223114_at | 0.1932 | 0.3750 | |
| GSE97050 | COQ5 | 84274 | A_33_P3213512 | 0.0611 | 0.8113 | |
| SRP007169 | COQ5 | 84274 | RNAseq | 0.1886 | 0.6866 | |
| SRP008496 | COQ5 | 84274 | RNAseq | 0.2131 | 0.4748 | |
| SRP064894 | COQ5 | 84274 | RNAseq | 0.0439 | 0.7678 | |
| SRP133303 | COQ5 | 84274 | RNAseq | 0.1725 | 0.2968 | |
| SRP159526 | COQ5 | 84274 | RNAseq | 0.0710 | 0.7097 | |
| SRP193095 | COQ5 | 84274 | RNAseq | -0.2727 | 0.0131 | |
| SRP219564 | COQ5 | 84274 | RNAseq | -0.3157 | 0.3243 | |
| TCGA | COQ5 | 84274 | RNAseq | 0.0149 | 0.8034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COQ5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ5 | 84274 | 6 | 2 | 22 | |
| GSE20123 | COQ5 | 84274 | 6 | 2 | 22 | |
| GSE43470 | COQ5 | 84274 | 2 | 2 | 39 | |
| GSE46452 | COQ5 | 84274 | 9 | 1 | 49 | |
| GSE47630 | COQ5 | 84274 | 9 | 3 | 28 | |
| GSE54993 | COQ5 | 84274 | 0 | 5 | 65 | |
| GSE54994 | COQ5 | 84274 | 7 | 6 | 40 | |
| GSE60625 | COQ5 | 84274 | 0 | 0 | 11 | |
| GSE74703 | COQ5 | 84274 | 2 | 1 | 33 | |
| GSE74704 | COQ5 | 84274 | 3 | 2 | 15 | |
| TCGA | COQ5 | 84274 | 19 | 12 | 65 |
Total number of gains: 63; Total number of losses: 36; Total Number of normals: 389.
Somatic mutations of COQ5:
Generating mutation plots.
Highly correlated genes for COQ5:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ5 | BTBD3 | 0.736837 | 3 | 0 | 3 |
| COQ5 | CENPC | 0.687949 | 3 | 0 | 3 |
| COQ5 | OSBPL11 | 0.658564 | 3 | 0 | 3 |
| COQ5 | BUD13 | 0.637415 | 4 | 0 | 3 |
| COQ5 | BEND7 | 0.615816 | 3 | 0 | 3 |
| COQ5 | MID1 | 0.611208 | 4 | 0 | 3 |
| COQ5 | C16orf91 | 0.604524 | 4 | 0 | 3 |
| COQ5 | PSMB9 | 0.586192 | 3 | 0 | 3 |
| COQ5 | PEX7 | 0.582655 | 5 | 0 | 3 |
| COQ5 | PTPRC | 0.565745 | 3 | 0 | 3 |
| COQ5 | SUMO1 | 0.561141 | 4 | 0 | 3 |
| COQ5 | SFT2D1 | 0.55654 | 4 | 0 | 3 |
| COQ5 | YEATS4 | 0.555219 | 8 | 0 | 5 |
| COQ5 | METTL18 | 0.548783 | 6 | 0 | 4 |
| COQ5 | POC1B | 0.542554 | 5 | 0 | 3 |
| COQ5 | TXNL4B | 0.5422 | 4 | 0 | 3 |
| COQ5 | UNC50 | 0.538082 | 5 | 0 | 3 |
| COQ5 | ISCU | 0.536925 | 5 | 0 | 3 |
| COQ5 | NUP37 | 0.523523 | 6 | 0 | 3 |
| COQ5 | INTS5 | 0.518807 | 4 | 0 | 3 |
For details and further investigation, click here
