| Full name: transmembrane protein 125 | Alias Symbol: MGC17299 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 128218 | HGNC ID: HGNC:28275 | Ensembl Gene: ENSG00000179178 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM125:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM125 | 128218 | 225822_at | -0.7964 | 0.1885 | |
| GSE26886 | TMEM125 | 128218 | 225822_at | -1.7601 | 0.0000 | |
| GSE45670 | TMEM125 | 128218 | 225822_at | 0.0513 | 0.8691 | |
| GSE53622 | TMEM125 | 128218 | 52401 | -0.4141 | 0.0000 | |
| GSE53624 | TMEM125 | 128218 | 52401 | -0.8124 | 0.0000 | |
| GSE63941 | TMEM125 | 128218 | 225822_at | 2.7096 | 0.0108 | |
| GSE77861 | TMEM125 | 128218 | 225822_at | -0.5589 | 0.0072 | |
| GSE97050 | TMEM125 | 128218 | A_23_P115022 | -0.0061 | 0.9811 | |
| SRP007169 | TMEM125 | 128218 | RNAseq | -2.4945 | 0.0000 | |
| SRP008496 | TMEM125 | 128218 | RNAseq | -2.3622 | 0.0000 | |
| SRP064894 | TMEM125 | 128218 | RNAseq | -1.6733 | 0.0007 | |
| SRP133303 | TMEM125 | 128218 | RNAseq | -1.5279 | 0.0000 | |
| SRP159526 | TMEM125 | 128218 | RNAseq | -1.6195 | 0.0000 | |
| SRP193095 | TMEM125 | 128218 | RNAseq | -1.3911 | 0.0001 | |
| SRP219564 | TMEM125 | 128218 | RNAseq | -2.1461 | 0.0507 | |
| TCGA | TMEM125 | 128218 | RNAseq | -1.0911 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 8.
Survival by TMEM125 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM125:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM125 | 128218 | 4 | 3 | 23 | |
| GSE20123 | TMEM125 | 128218 | 4 | 2 | 24 | |
| GSE43470 | TMEM125 | 128218 | 7 | 2 | 34 | |
| GSE46452 | TMEM125 | 128218 | 3 | 1 | 55 | |
| GSE47630 | TMEM125 | 128218 | 9 | 2 | 29 | |
| GSE54993 | TMEM125 | 128218 | 0 | 2 | 68 | |
| GSE54994 | TMEM125 | 128218 | 13 | 2 | 38 | |
| GSE60625 | TMEM125 | 128218 | 0 | 0 | 11 | |
| GSE74703 | TMEM125 | 128218 | 6 | 1 | 29 | |
| GSE74704 | TMEM125 | 128218 | 2 | 0 | 18 | |
| TCGA | TMEM125 | 128218 | 13 | 16 | 67 |
Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.
Somatic mutations of TMEM125:
Generating mutation plots.
Highly correlated genes for TMEM125:
Showing top 20/656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM125 | TEN1 | 0.805217 | 3 | 0 | 3 |
| TMEM125 | MFSD2B | 0.794147 | 3 | 0 | 3 |
| TMEM125 | ENTPD8 | 0.791576 | 3 | 0 | 3 |
| TMEM125 | CLDN24 | 0.776578 | 3 | 0 | 3 |
| TMEM125 | MFSD11 | 0.770224 | 3 | 0 | 3 |
| TMEM125 | KRTAP20-1 | 0.767357 | 3 | 0 | 3 |
| TMEM125 | PAX8 | 0.764207 | 3 | 0 | 3 |
| TMEM125 | OR2Z1 | 0.762846 | 3 | 0 | 3 |
| TMEM125 | CD164L2 | 0.759395 | 3 | 0 | 3 |
| TMEM125 | GDF7 | 0.748865 | 3 | 0 | 3 |
| TMEM125 | FAM163B | 0.73828 | 3 | 0 | 3 |
| TMEM125 | DHRS7B | 0.737793 | 3 | 0 | 3 |
| TMEM125 | KRTAP6-1 | 0.736722 | 3 | 0 | 3 |
| TMEM125 | ZDHHC20 | 0.734749 | 4 | 0 | 4 |
| TMEM125 | TDGF1 | 0.733804 | 3 | 0 | 3 |
| TMEM125 | GPR78 | 0.733032 | 3 | 0 | 3 |
| TMEM125 | OR10G8 | 0.73199 | 3 | 0 | 3 |
| TMEM125 | PAFAH2 | 0.729924 | 5 | 0 | 5 |
| TMEM125 | B3GALT4 | 0.728521 | 3 | 0 | 3 |
| TMEM125 | RNF186 | 0.713495 | 3 | 0 | 3 |
For details and further investigation, click here
