| Full name: polyamine oxidase | Alias Symbol: PAO | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 196743 | HGNC ID: HGNC:20837 | Ensembl Gene: ENSG00000148832 | OMIM ID: 615853 |
| Drug and gene relationship at DGIdb | |||
Expression of PAOX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAOX | 196743 | 50400_at | -0.3647 | 0.4501 | |
| GSE20347 | PAOX | 196743 | 50400_at | -0.7787 | 0.0000 | |
| GSE23400 | PAOX | 196743 | 221941_at | -0.3450 | 0.0000 | |
| GSE26886 | PAOX | 196743 | 221941_at | -0.1103 | 0.4174 | |
| GSE29001 | PAOX | 196743 | 50400_at | -0.9335 | 0.0045 | |
| GSE38129 | PAOX | 196743 | 50400_at | -0.6558 | 0.0000 | |
| GSE45670 | PAOX | 196743 | 50400_at | -0.0970 | 0.6386 | |
| GSE53622 | PAOX | 196743 | 23885 | -0.7399 | 0.0000 | |
| GSE53624 | PAOX | 196743 | 23885 | -0.8638 | 0.0000 | |
| GSE63941 | PAOX | 196743 | 221941_at | -0.2378 | 0.3133 | |
| GSE77861 | PAOX | 196743 | 221941_at | -0.1069 | 0.6102 | |
| GSE97050 | PAOX | 196743 | A_23_P385771 | -0.0541 | 0.8627 | |
| SRP007169 | PAOX | 196743 | RNAseq | -2.0174 | 0.0003 | |
| SRP064894 | PAOX | 196743 | RNAseq | -0.8627 | 0.0031 | |
| SRP133303 | PAOX | 196743 | RNAseq | -0.8600 | 0.0000 | |
| SRP159526 | PAOX | 196743 | RNAseq | -1.2141 | 0.0014 | |
| SRP193095 | PAOX | 196743 | RNAseq | -0.6675 | 0.0000 | |
| SRP219564 | PAOX | 196743 | RNAseq | -0.9963 | 0.0110 | |
| TCGA | PAOX | 196743 | RNAseq | 0.0092 | 0.9309 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PAOX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAOX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAOX | 196743 | 3 | 8 | 19 | |
| GSE20123 | PAOX | 196743 | 3 | 9 | 18 | |
| GSE43470 | PAOX | 196743 | 0 | 8 | 35 | |
| GSE46452 | PAOX | 196743 | 1 | 11 | 47 | |
| GSE47630 | PAOX | 196743 | 4 | 13 | 23 | |
| GSE54993 | PAOX | 196743 | 8 | 2 | 60 | |
| GSE54994 | PAOX | 196743 | 1 | 9 | 43 | |
| GSE60625 | PAOX | 196743 | 0 | 0 | 11 | |
| GSE74703 | PAOX | 196743 | 0 | 6 | 30 | |
| GSE74704 | PAOX | 196743 | 3 | 4 | 13 | |
| TCGA | PAOX | 196743 | 7 | 28 | 61 |
Total number of gains: 30; Total number of losses: 98; Total Number of normals: 360.
Somatic mutations of PAOX:
Generating mutation plots.
Highly correlated genes for PAOX:
Showing top 20/614 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAOX | NPY2R | 0.758092 | 3 | 0 | 3 |
| PAOX | MFSD2B | 0.756476 | 3 | 0 | 3 |
| PAOX | TRIM41 | 0.753537 | 3 | 0 | 3 |
| PAOX | FAM163B | 0.753429 | 3 | 0 | 3 |
| PAOX | KRTAP20-1 | 0.744673 | 3 | 0 | 3 |
| PAOX | CCDC22 | 0.732629 | 4 | 0 | 4 |
| PAOX | SLC25A47 | 0.732302 | 3 | 0 | 3 |
| PAOX | OR2Z1 | 0.732207 | 3 | 0 | 3 |
| PAOX | CCDC157 | 0.724334 | 3 | 0 | 3 |
| PAOX | PTGER1 | 0.715697 | 3 | 0 | 3 |
| PAOX | MUC22 | 0.711986 | 3 | 0 | 3 |
| PAOX | OR10G8 | 0.708171 | 3 | 0 | 3 |
| PAOX | NOBOX | 0.707651 | 3 | 0 | 3 |
| PAOX | OTOP3 | 0.706664 | 3 | 0 | 3 |
| PAOX | SMIM5 | 0.705453 | 4 | 0 | 4 |
| PAOX | FUZ | 0.699005 | 3 | 0 | 3 |
| PAOX | NCCRP1 | 0.697088 | 3 | 0 | 3 |
| PAOX | HMGB4 | 0.693267 | 4 | 0 | 4 |
| PAOX | FAM3B | 0.692618 | 4 | 0 | 4 |
| PAOX | CYP2E1 | 0.691338 | 9 | 0 | 8 |
For details and further investigation, click here
