| Full name: sorting nexin family member 21 | Alias Symbol: dJ337O18.4|SNX-L | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 90203 | HGNC ID: HGNC:16154 | Ensembl Gene: ENSG00000124104 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNX21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX21 | 90203 | 1553960_at | -0.4390 | 0.5803 | |
| GSE26886 | SNX21 | 90203 | 1553961_s_at | -0.0417 | 0.8925 | |
| GSE45670 | SNX21 | 90203 | 1553960_at | -1.0376 | 0.0001 | |
| GSE53622 | SNX21 | 90203 | 77291 | -0.4979 | 0.0000 | |
| GSE53624 | SNX21 | 90203 | 77291 | -0.8141 | 0.0000 | |
| GSE63941 | SNX21 | 90203 | 1553960_at | -2.3988 | 0.0280 | |
| GSE77861 | SNX21 | 90203 | 226595_at | -0.1717 | 0.3749 | |
| GSE97050 | SNX21 | 90203 | A_23_P154585 | -0.2938 | 0.2240 | |
| SRP007169 | SNX21 | 90203 | RNAseq | -2.5633 | 0.0000 | |
| SRP008496 | SNX21 | 90203 | RNAseq | -1.9479 | 0.0000 | |
| SRP064894 | SNX21 | 90203 | RNAseq | -0.5212 | 0.0716 | |
| SRP133303 | SNX21 | 90203 | RNAseq | -0.7335 | 0.0000 | |
| SRP159526 | SNX21 | 90203 | RNAseq | -0.6598 | 0.0175 | |
| SRP193095 | SNX21 | 90203 | RNAseq | -0.6255 | 0.0000 | |
| SRP219564 | SNX21 | 90203 | RNAseq | -0.6692 | 0.1388 | |
| TCGA | SNX21 | 90203 | RNAseq | -0.2076 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SNX21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX21 | 90203 | 14 | 1 | 15 | |
| GSE20123 | SNX21 | 90203 | 14 | 1 | 15 | |
| GSE43470 | SNX21 | 90203 | 12 | 1 | 30 | |
| GSE46452 | SNX21 | 90203 | 29 | 0 | 30 | |
| GSE47630 | SNX21 | 90203 | 24 | 1 | 15 | |
| GSE54993 | SNX21 | 90203 | 0 | 18 | 52 | |
| GSE54994 | SNX21 | 90203 | 25 | 0 | 28 | |
| GSE60625 | SNX21 | 90203 | 0 | 0 | 11 | |
| GSE74703 | SNX21 | 90203 | 10 | 1 | 25 | |
| GSE74704 | SNX21 | 90203 | 10 | 0 | 10 | |
| TCGA | SNX21 | 90203 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 26; Total Number of normals: 278.
Somatic mutations of SNX21:
Generating mutation plots.
Highly correlated genes for SNX21:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX21 | FAM163B | 0.763023 | 3 | 0 | 3 |
| SNX21 | MFSD2B | 0.746135 | 3 | 0 | 3 |
| SNX21 | BTNL9 | 0.742115 | 3 | 0 | 3 |
| SNX21 | OR10G8 | 0.736359 | 3 | 0 | 3 |
| SNX21 | TTC21A | 0.723819 | 3 | 0 | 3 |
| SNX21 | KRTAP20-1 | 0.722942 | 3 | 0 | 3 |
| SNX21 | CRYGA | 0.722058 | 3 | 0 | 3 |
| SNX21 | MAFG | 0.717192 | 3 | 0 | 3 |
| SNX21 | NACAD | 0.713699 | 3 | 0 | 3 |
| SNX21 | OR2Z1 | 0.707602 | 3 | 0 | 3 |
| SNX21 | BARHL2 | 0.702544 | 3 | 0 | 3 |
| SNX21 | GAB2 | 0.697344 | 5 | 0 | 5 |
| SNX21 | CD164L2 | 0.696369 | 3 | 0 | 3 |
| SNX21 | ZNF235 | 0.690815 | 3 | 0 | 3 |
| SNX21 | NHLRC4 | 0.689387 | 4 | 0 | 3 |
| SNX21 | IGLON5 | 0.688109 | 3 | 0 | 3 |
| SNX21 | GID4 | 0.687537 | 4 | 0 | 4 |
| SNX21 | NUDT13 | 0.677285 | 3 | 0 | 3 |
| SNX21 | RGS12 | 0.672375 | 4 | 0 | 3 |
| SNX21 | MUC22 | 0.671423 | 3 | 0 | 3 |
For details and further investigation, click here
