PLIN5

 

Full name: perilipin 5 Alias Symbol: LSDP5|LSDA5|OXPAT|MLDP
Type: protein-coding gene Cytoband: 19p13.3
Entrez ID: 440503 HGNC ID: HGNC:33196 Ensembl Gene: ENSG00000214456 OMIM ID: 613248
Drug and gene relationship at DGIdb

 

Expression of PLIN5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PLIN5 440503 1568667_s_at -0.0521 0.8804
GSE26886 PLIN5 440503 1568667_s_at -0.0526 0.6873
GSE45670 PLIN5 440503 1568667_s_at 0.1304 0.2835
GSE53622 PLIN5 440503 139274 -1.2884 0.0000
GSE53624 PLIN5 440503 139274 -1.1253 0.0000
GSE63941 PLIN5 440503 1568667_s_at 0.1005 0.4836
GSE77861 PLIN5 440503 1568667_s_at -0.1430 0.1665
GSE97050 PLIN5 440503 A_23_P39251 0.3847 0.3265
SRP064894 PLIN5 440503 RNAseq -0.0589 0.8651
SRP133303 PLIN5 440503 RNAseq -0.1417 0.4454
SRP159526 PLIN5 440503 RNAseq -0.7813 0.0799
SRP193095 PLIN5 440503 RNAseq -0.0381 0.8140
SRP219564 PLIN5 440503 RNAseq -0.3941 0.5435
TCGA PLIN5 440503 RNAseq -2.2133 0.0000

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by PLIN5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PLIN5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PLIN5 440503 5 3 22
GSE20123 PLIN5 440503 4 2 24
GSE43470 PLIN5 440503 1 8 34
GSE46452 PLIN5 440503 47 1 11
GSE47630 PLIN5 440503 5 7 28
GSE54993 PLIN5 440503 16 3 51
GSE54994 PLIN5 440503 6 16 31
GSE60625 PLIN5 440503 9 0 2
GSE74703 PLIN5 440503 1 5 30
GSE74704 PLIN5 440503 1 2 17
TCGA PLIN5 440503 12 18 66

Total number of gains: 107; Total number of losses: 65; Total Number of normals: 316.  


 

Somatic mutations of PLIN5:

 

Generating mutation plots.

 

Highly correlated genes for PLIN5:

 

Showing top 20/71 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLIN5RTP50.76654303
PLIN5LYPD50.684475303
PLIN5OR5L20.667862303
PLIN5RGN0.650088303
PLIN5CARHSP10.646214404
PLIN5LMTK30.636355303
PLIN5STH0.633391404
PLIN5HSD17B20.631674403
PLIN5KIF120.623618404
PLIN5SHPK0.622486303
PLIN5PPP4R10.615459303
PLIN5TMC50.614051403
PLIN5FOXS10.610117303
PLIN5TRIM130.601987403
PLIN5DNAJB70.598813303
PLIN5C3orf220.591709303
PLIN5LINC009220.586002403
PLIN5FCAR0.577989403
PLIN5CCDC270.574713303
PLIN5ZNF7470.570349303

For details and further investigation, click here