| Full name: saitohin | Alias Symbol: MAPTIT | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 246744 | HGNC ID: HGNC:18839 | Ensembl Gene: ENSG00000256762 | OMIM ID: 607067 |
| Drug and gene relationship at DGIdb | |||
Expression of STH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STH | 246744 | 1555752_at | -0.2170 | 0.2170 | |
| GSE26886 | STH | 246744 | 1555752_at | -0.1635 | 0.2716 | |
| GSE45670 | STH | 246744 | 1555752_at | 0.0142 | 0.9073 | |
| GSE53622 | STH | 246744 | 46352 | -0.1703 | 0.1087 | |
| GSE53624 | STH | 246744 | 46352 | -0.3849 | 0.0000 | |
| GSE63941 | STH | 246744 | 1555752_at | 0.2953 | 0.0495 | |
| GSE77861 | STH | 246744 | 1555752_at | -0.2948 | 0.0291 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STH | 246744 | 6 | 2 | 22 | |
| GSE20123 | STH | 246744 | 6 | 2 | 22 | |
| GSE43470 | STH | 246744 | 1 | 2 | 40 | |
| GSE46452 | STH | 246744 | 32 | 0 | 27 | |
| GSE47630 | STH | 246744 | 9 | 0 | 31 | |
| GSE54993 | STH | 246744 | 3 | 4 | 63 | |
| GSE54994 | STH | 246744 | 9 | 6 | 38 | |
| GSE60625 | STH | 246744 | 4 | 0 | 7 | |
| GSE74703 | STH | 246744 | 1 | 1 | 34 | |
| GSE74704 | STH | 246744 | 4 | 1 | 15 | |
| TCGA | STH | 246744 | 26 | 7 | 63 |
Total number of gains: 101; Total number of losses: 25; Total Number of normals: 362.
Somatic mutations of STH:
Generating mutation plots.
Highly correlated genes for STH:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STH | CNTFR | 0.726307 | 3 | 0 | 3 |
| STH | ARMC4 | 0.707039 | 3 | 0 | 3 |
| STH | UBE2D2 | 0.691503 | 3 | 0 | 3 |
| STH | KIF25 | 0.688074 | 3 | 0 | 3 |
| STH | RNF141 | 0.671061 | 3 | 0 | 3 |
| STH | TEC | 0.670867 | 3 | 0 | 3 |
| STH | C14orf180 | 0.670174 | 3 | 0 | 3 |
| STH | IL17RC | 0.667749 | 6 | 0 | 6 |
| STH | ABCA4 | 0.66617 | 3 | 0 | 3 |
| STH | OR12D2 | 0.66353 | 3 | 0 | 3 |
| STH | ANHX | 0.661515 | 3 | 0 | 3 |
| STH | CTSG | 0.651967 | 3 | 0 | 3 |
| STH | PDE6G | 0.645331 | 4 | 0 | 4 |
| STH | C1orf61 | 0.642083 | 4 | 0 | 3 |
| STH | LMAN2 | 0.638307 | 3 | 0 | 3 |
| STH | RTP5 | 0.637392 | 5 | 0 | 3 |
| STH | LRRC29 | 0.636991 | 5 | 0 | 4 |
| STH | SFMBT2 | 0.635909 | 3 | 0 | 3 |
| STH | RASAL1 | 0.635894 | 3 | 0 | 3 |
| STH | IK | 0.635141 | 3 | 0 | 3 |
For details and further investigation, click here
