| Full name: kinesin family member 12 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 113220 | HGNC ID: HGNC:21495 | Ensembl Gene: ENSG00000136883 | OMIM ID: 611278 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF12 | 113220 | 229258_at | -0.0591 | 0.8313 | |
| GSE26886 | KIF12 | 113220 | 229258_at | -0.0427 | 0.7890 | |
| GSE45670 | KIF12 | 113220 | 229258_at | 0.0200 | 0.8970 | |
| GSE53622 | KIF12 | 113220 | 23147 | -0.7068 | 0.0000 | |
| GSE53624 | KIF12 | 113220 | 23147 | -0.6055 | 0.0000 | |
| GSE63941 | KIF12 | 113220 | 229258_at | 0.1454 | 0.3092 | |
| GSE77861 | KIF12 | 113220 | 229258_at | -0.2494 | 0.0441 | |
| TCGA | KIF12 | 113220 | RNAseq | -1.2115 | 0.0348 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KIF12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF12 | 113220 | 3 | 10 | 17 | |
| GSE20123 | KIF12 | 113220 | 3 | 11 | 16 | |
| GSE43470 | KIF12 | 113220 | 4 | 3 | 36 | |
| GSE46452 | KIF12 | 113220 | 6 | 13 | 40 | |
| GSE47630 | KIF12 | 113220 | 3 | 16 | 21 | |
| GSE54993 | KIF12 | 113220 | 3 | 3 | 64 | |
| GSE54994 | KIF12 | 113220 | 9 | 9 | 35 | |
| GSE60625 | KIF12 | 113220 | 0 | 0 | 11 | |
| GSE74703 | KIF12 | 113220 | 4 | 3 | 29 | |
| GSE74704 | KIF12 | 113220 | 2 | 7 | 11 | |
| TCGA | KIF12 | 113220 | 26 | 22 | 48 |
Total number of gains: 63; Total number of losses: 97; Total Number of normals: 328.
Somatic mutations of KIF12:
Generating mutation plots.
Highly correlated genes for KIF12:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF12 | HCN1 | 0.687797 | 3 | 0 | 3 |
| KIF12 | CBLN4 | 0.680979 | 4 | 0 | 4 |
| KIF12 | C10orf71-AS1 | 0.677724 | 3 | 0 | 3 |
| KIF12 | ZFHX2 | 0.673986 | 3 | 0 | 3 |
| KIF12 | PTK6 | 0.670106 | 4 | 0 | 3 |
| KIF12 | ZNF214 | 0.667871 | 3 | 0 | 3 |
| KIF12 | DCD | 0.666679 | 6 | 0 | 5 |
| KIF12 | PLEKHN1 | 0.663826 | 4 | 0 | 4 |
| KIF12 | HMGB4 | 0.663583 | 3 | 0 | 3 |
| KIF12 | LINC00868 | 0.662286 | 3 | 0 | 3 |
| KIF12 | NDUFB2-AS1 | 0.661299 | 4 | 0 | 3 |
| KIF12 | PALM3 | 0.659821 | 3 | 0 | 3 |
| KIF12 | ETFDH | 0.657343 | 3 | 0 | 3 |
| KIF12 | KIF6 | 0.65625 | 3 | 0 | 3 |
| KIF12 | RPS6KA2-AS1 | 0.655977 | 3 | 0 | 3 |
| KIF12 | IVL | 0.65195 | 3 | 0 | 3 |
| KIF12 | PRAP1 | 0.649929 | 4 | 0 | 3 |
| KIF12 | NKD1 | 0.649746 | 3 | 0 | 3 |
| KIF12 | PRRG3 | 0.649369 | 5 | 0 | 5 |
| KIF12 | PRR29 | 0.64841 | 4 | 0 | 4 |
For details and further investigation, click here
