| Full name: forkhead box S1 | Alias Symbol: FREAC10 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 2307 | HGNC ID: HGNC:3735 | Ensembl Gene: ENSG00000179772 | OMIM ID: 602939 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXS1 | 2307 | 229731_at | 0.5945 | 0.0377 | |
| GSE26886 | FOXS1 | 2307 | 229731_at | 0.2818 | 0.1044 | |
| GSE45670 | FOXS1 | 2307 | 229731_at | -0.0377 | 0.8220 | |
| GSE53622 | FOXS1 | 2307 | 5280 | 0.7510 | 0.0000 | |
| GSE53624 | FOXS1 | 2307 | 5280 | 1.2717 | 0.0000 | |
| GSE63941 | FOXS1 | 2307 | 229731_at | 0.0575 | 0.8402 | |
| GSE77861 | FOXS1 | 2307 | 229731_at | -0.0786 | 0.5363 | |
| GSE97050 | FOXS1 | 2307 | A_33_P3283833 | 0.3503 | 0.3547 | |
| SRP007169 | FOXS1 | 2307 | RNAseq | 5.2087 | 0.0002 | |
| SRP064894 | FOXS1 | 2307 | RNAseq | 2.4548 | 0.0000 | |
| SRP133303 | FOXS1 | 2307 | RNAseq | 0.1861 | 0.6212 | |
| SRP159526 | FOXS1 | 2307 | RNAseq | 0.3111 | 0.6050 | |
| SRP219564 | FOXS1 | 2307 | RNAseq | 1.4327 | 0.0078 | |
| TCGA | FOXS1 | 2307 | RNAseq | 1.4338 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by FOXS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXS1 | 2307 | 15 | 0 | 15 | |
| GSE20123 | FOXS1 | 2307 | 15 | 0 | 15 | |
| GSE43470 | FOXS1 | 2307 | 11 | 0 | 32 | |
| GSE46452 | FOXS1 | 2307 | 29 | 0 | 30 | |
| GSE47630 | FOXS1 | 2307 | 25 | 0 | 15 | |
| GSE54993 | FOXS1 | 2307 | 0 | 18 | 52 | |
| GSE54994 | FOXS1 | 2307 | 27 | 1 | 25 | |
| GSE60625 | FOXS1 | 2307 | 0 | 0 | 11 | |
| GSE74703 | FOXS1 | 2307 | 10 | 0 | 26 | |
| GSE74704 | FOXS1 | 2307 | 10 | 0 | 10 | |
| TCGA | FOXS1 | 2307 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 20; Total Number of normals: 277.
Somatic mutations of FOXS1:
Generating mutation plots.
Highly correlated genes for FOXS1:
Showing top 20/423 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXS1 | NGB | 0.707877 | 3 | 0 | 3 |
| FOXS1 | INHBE | 0.70287 | 3 | 0 | 3 |
| FOXS1 | CLEC11A | 0.699471 | 4 | 0 | 4 |
| FOXS1 | NEU1 | 0.685929 | 3 | 0 | 3 |
| FOXS1 | ATF5 | 0.685253 | 3 | 0 | 3 |
| FOXS1 | ANKRD13B | 0.679097 | 3 | 0 | 3 |
| FOXS1 | BGN | 0.670519 | 5 | 0 | 5 |
| FOXS1 | PSMB3 | 0.667492 | 4 | 0 | 3 |
| FOXS1 | PCGF1 | 0.667324 | 4 | 0 | 3 |
| FOXS1 | CEP128 | 0.666237 | 4 | 0 | 4 |
| FOXS1 | MRPL55 | 0.660887 | 3 | 0 | 3 |
| FOXS1 | CDK18 | 0.653563 | 3 | 0 | 3 |
| FOXS1 | FRS3 | 0.648945 | 3 | 0 | 3 |
| FOXS1 | NEDD8 | 0.647126 | 3 | 0 | 3 |
| FOXS1 | BRMS1 | 0.646735 | 3 | 0 | 3 |
| FOXS1 | LMAN2L | 0.639071 | 4 | 0 | 3 |
| FOXS1 | GIT1 | 0.636924 | 4 | 0 | 4 |
| FOXS1 | LBX2-AS1 | 0.634491 | 4 | 0 | 3 |
| FOXS1 | MIER2 | 0.632861 | 3 | 0 | 3 |
| FOXS1 | CD37 | 0.632804 | 3 | 0 | 3 |
For details and further investigation, click here
