| Full name: DnaJ heat shock protein family (Hsp40) member B7 | Alias Symbol: HSC3 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 150353 | HGNC ID: HGNC:24986 | Ensembl Gene: ENSG00000172404 | OMIM ID: 611336 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJB7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB7 | 150353 | 1552675_at | -0.0843 | 0.6676 | |
| GSE26886 | DNAJB7 | 150353 | 1552675_at | -0.0701 | 0.3499 | |
| GSE45670 | DNAJB7 | 150353 | 1552675_at | -0.0109 | 0.8937 | |
| GSE53622 | DNAJB7 | 150353 | 126631 | 0.1791 | 0.0479 | |
| GSE53624 | DNAJB7 | 150353 | 126631 | 0.2182 | 0.0168 | |
| GSE63941 | DNAJB7 | 150353 | 1552675_at | 0.4462 | 0.0100 | |
| GSE77861 | DNAJB7 | 150353 | 1552675_at | -0.0727 | 0.3341 | |
| GSE97050 | DNAJB7 | 150353 | A_23_P351168 | 0.1212 | 0.5458 | |
| SRP133303 | DNAJB7 | 150353 | RNAseq | -0.0273 | 0.8611 | |
| SRP193095 | DNAJB7 | 150353 | RNAseq | 0.0573 | 0.7148 | |
| TCGA | DNAJB7 | 150353 | RNAseq | 0.4696 | 0.1116 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJB7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB7 | 150353 | 6 | 5 | 19 | |
| GSE20123 | DNAJB7 | 150353 | 6 | 4 | 20 | |
| GSE43470 | DNAJB7 | 150353 | 4 | 6 | 33 | |
| GSE46452 | DNAJB7 | 150353 | 31 | 2 | 26 | |
| GSE47630 | DNAJB7 | 150353 | 9 | 4 | 27 | |
| GSE54993 | DNAJB7 | 150353 | 3 | 6 | 61 | |
| GSE54994 | DNAJB7 | 150353 | 11 | 7 | 35 | |
| GSE60625 | DNAJB7 | 150353 | 5 | 0 | 6 | |
| GSE74703 | DNAJB7 | 150353 | 4 | 4 | 28 | |
| GSE74704 | DNAJB7 | 150353 | 3 | 2 | 15 | |
| TCGA | DNAJB7 | 150353 | 26 | 15 | 55 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of DNAJB7:
Generating mutation plots.
Highly correlated genes for DNAJB7:
Showing top 20/157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB7 | PRKCH | 0.778578 | 3 | 0 | 3 |
| DNAJB7 | GRIA4 | 0.750594 | 3 | 0 | 3 |
| DNAJB7 | UBE2J1 | 0.737054 | 3 | 0 | 3 |
| DNAJB7 | ROPN1 | 0.735798 | 3 | 0 | 3 |
| DNAJB7 | STX11 | 0.733084 | 3 | 0 | 3 |
| DNAJB7 | TOM1 | 0.728926 | 3 | 0 | 3 |
| DNAJB7 | CCNC | 0.722781 | 3 | 0 | 3 |
| DNAJB7 | GALE | 0.718201 | 3 | 0 | 3 |
| DNAJB7 | ABLIM2 | 0.716137 | 3 | 0 | 3 |
| DNAJB7 | TYSND1 | 0.714996 | 3 | 0 | 3 |
| DNAJB7 | COPZ1 | 0.708667 | 3 | 0 | 3 |
| DNAJB7 | CRB3 | 0.707511 | 3 | 0 | 3 |
| DNAJB7 | CERS4 | 0.705251 | 3 | 0 | 3 |
| DNAJB7 | OSTF1 | 0.700479 | 3 | 0 | 3 |
| DNAJB7 | DHX32 | 0.698178 | 3 | 0 | 3 |
| DNAJB7 | DCXR | 0.693212 | 3 | 0 | 3 |
| DNAJB7 | SMPD2 | 0.691102 | 3 | 0 | 3 |
| DNAJB7 | CHIC2 | 0.690587 | 3 | 0 | 3 |
| DNAJB7 | PEX3 | 0.689359 | 3 | 0 | 3 |
| DNAJB7 | FYTTD1 | 0.683502 | 3 | 0 | 3 |
For details and further investigation, click here
