| Full name: lemur tyrosine kinase 3 | Alias Symbol: KIAA1883|LMR3|TYKLM3|PPP1R101 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 114783 | HGNC ID: HGNC:19295 | Ensembl Gene: ENSG00000142235 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LMTK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMTK3 | 114783 | 1557103_a_at | 0.3040 | 0.3306 | |
| GSE26886 | LMTK3 | 114783 | 1557103_a_at | 0.0695 | 0.6780 | |
| GSE45670 | LMTK3 | 114783 | 1557103_a_at | 0.2362 | 0.0108 | |
| GSE63941 | LMTK3 | 114783 | 1557103_a_at | 0.5752 | 0.1248 | |
| GSE77861 | LMTK3 | 114783 | 1557103_a_at | -0.0581 | 0.7400 | |
| GSE97050 | LMTK3 | 114783 | A_33_P3266928 | 0.3079 | 0.4953 | |
| SRP007169 | LMTK3 | 114783 | RNAseq | -0.7436 | 0.1244 | |
| SRP064894 | LMTK3 | 114783 | RNAseq | -0.0982 | 0.8112 | |
| SRP133303 | LMTK3 | 114783 | RNAseq | -0.0410 | 0.9073 | |
| SRP159526 | LMTK3 | 114783 | RNAseq | -0.2185 | 0.5050 | |
| SRP193095 | LMTK3 | 114783 | RNAseq | -0.1288 | 0.4655 | |
| SRP219564 | LMTK3 | 114783 | RNAseq | -0.9806 | 0.1391 | |
| TCGA | LMTK3 | 114783 | RNAseq | 0.3053 | 0.0601 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LMTK3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LMTK3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMTK3 | 114783 | 4 | 4 | 22 | |
| GSE20123 | LMTK3 | 114783 | 4 | 3 | 23 | |
| GSE43470 | LMTK3 | 114783 | 4 | 11 | 28 | |
| GSE46452 | LMTK3 | 114783 | 45 | 1 | 13 | |
| GSE47630 | LMTK3 | 114783 | 9 | 6 | 25 | |
| GSE54993 | LMTK3 | 114783 | 17 | 4 | 49 | |
| GSE54994 | LMTK3 | 114783 | 4 | 14 | 35 | |
| GSE60625 | LMTK3 | 114783 | 9 | 0 | 2 | |
| GSE74703 | LMTK3 | 114783 | 4 | 7 | 25 | |
| GSE74704 | LMTK3 | 114783 | 4 | 1 | 15 | |
| TCGA | LMTK3 | 114783 | 14 | 18 | 64 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of LMTK3:
Generating mutation plots.
Highly correlated genes for LMTK3:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMTK3 | MAGOHB | 0.66992 | 3 | 0 | 3 |
| LMTK3 | FGF11 | 0.656546 | 3 | 0 | 3 |
| LMTK3 | LAX1 | 0.646073 | 3 | 0 | 3 |
| LMTK3 | ASPSCR1 | 0.63856 | 3 | 0 | 3 |
| LMTK3 | PLIN5 | 0.636355 | 3 | 0 | 3 |
| LMTK3 | NOC2L | 0.630675 | 3 | 0 | 3 |
| LMTK3 | HSPBP1 | 0.627247 | 3 | 0 | 3 |
| LMTK3 | LINC00853 | 0.626347 | 3 | 0 | 3 |
| LMTK3 | SIDT1 | 0.625266 | 3 | 0 | 3 |
| LMTK3 | CKM | 0.624203 | 4 | 0 | 4 |
| LMTK3 | LEMD2 | 0.62311 | 3 | 0 | 3 |
| LMTK3 | TSC22D4 | 0.61416 | 3 | 0 | 3 |
| LMTK3 | HCAR1 | 0.613584 | 3 | 0 | 3 |
| LMTK3 | JOSD2 | 0.612056 | 3 | 0 | 3 |
| LMTK3 | CHRNE | 0.606796 | 3 | 0 | 3 |
| LMTK3 | C1orf159 | 0.605058 | 3 | 0 | 3 |
| LMTK3 | ADRM1 | 0.603842 | 3 | 0 | 3 |
| LMTK3 | FAM9C | 0.59882 | 4 | 0 | 3 |
| LMTK3 | DNAJC11 | 0.596207 | 3 | 0 | 3 |
| LMTK3 | TFDP3 | 0.596092 | 3 | 0 | 3 |
For details and further investigation, click here
