| Full name: lipase maturation factor 1 | Alias Symbol: FLJ12681|JFP11|FLJ22302|TMEM112A | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 64788 | HGNC ID: HGNC:14154 | Ensembl Gene: ENSG00000103227 | OMIM ID: 611761 |
| Drug and gene relationship at DGIdb | |||
Expression of LMF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMF1 | 64788 | 1569871_at | -0.0396 | 0.9251 | |
| GSE20347 | LMF1 | 64788 | 219135_s_at | -0.2563 | 0.0209 | |
| GSE23400 | LMF1 | 64788 | 219136_s_at | -0.2115 | 0.0000 | |
| GSE26886 | LMF1 | 64788 | 219135_s_at | -0.2066 | 0.1709 | |
| GSE29001 | LMF1 | 64788 | 219136_s_at | -0.2044 | 0.6233 | |
| GSE38129 | LMF1 | 64788 | 219135_s_at | -0.3948 | 0.0000 | |
| GSE45670 | LMF1 | 64788 | 1569871_at | 0.0802 | 0.4044 | |
| GSE53622 | LMF1 | 64788 | 10691 | -0.3521 | 0.0002 | |
| GSE53624 | LMF1 | 64788 | 82472 | -0.7197 | 0.0000 | |
| GSE63941 | LMF1 | 64788 | 1569871_at | 0.3862 | 0.0552 | |
| GSE77861 | LMF1 | 64788 | 1569871_at | 0.1601 | 0.1478 | |
| GSE97050 | LMF1 | 64788 | A_24_P18917 | -0.1900 | 0.5209 | |
| SRP007169 | LMF1 | 64788 | RNAseq | -1.2182 | 0.0062 | |
| SRP064894 | LMF1 | 64788 | RNAseq | -0.1005 | 0.7723 | |
| SRP133303 | LMF1 | 64788 | RNAseq | -0.2310 | 0.2168 | |
| SRP159526 | LMF1 | 64788 | RNAseq | 0.5694 | 0.2691 | |
| SRP193095 | LMF1 | 64788 | RNAseq | -0.3612 | 0.0209 | |
| SRP219564 | LMF1 | 64788 | RNAseq | 0.0958 | 0.8595 | |
| TCGA | LMF1 | 64788 | RNAseq | -0.4676 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LMF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMF1 | 64788 | 5 | 5 | 20 | |
| GSE20123 | LMF1 | 64788 | 5 | 4 | 21 | |
| GSE43470 | LMF1 | 64788 | 4 | 7 | 32 | |
| GSE46452 | LMF1 | 64788 | 38 | 1 | 20 | |
| GSE47630 | LMF1 | 64788 | 13 | 6 | 21 | |
| GSE54993 | LMF1 | 64788 | 3 | 5 | 62 | |
| GSE54994 | LMF1 | 64788 | 5 | 9 | 39 | |
| GSE60625 | LMF1 | 64788 | 4 | 0 | 7 | |
| GSE74703 | LMF1 | 64788 | 4 | 5 | 27 | |
| GSE74704 | LMF1 | 64788 | 3 | 2 | 15 | |
| TCGA | LMF1 | 64788 | 20 | 14 | 62 |
Total number of gains: 104; Total number of losses: 58; Total Number of normals: 326.
Somatic mutations of LMF1:
Generating mutation plots.
Highly correlated genes for LMF1:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMF1 | ESPNL | 0.773673 | 3 | 0 | 3 |
| LMF1 | CRABP1 | 0.751772 | 3 | 0 | 3 |
| LMF1 | SDK1 | 0.748528 | 3 | 0 | 3 |
| LMF1 | TMEM151B | 0.73098 | 3 | 0 | 3 |
| LMF1 | MEPE | 0.729552 | 4 | 0 | 4 |
| LMF1 | FRMD1 | 0.722396 | 4 | 0 | 4 |
| LMF1 | POU1F1 | 0.71402 | 3 | 0 | 3 |
| LMF1 | KLHL35 | 0.70636 | 3 | 0 | 3 |
| LMF1 | KRBA2 | 0.704775 | 3 | 0 | 3 |
| LMF1 | HAUS5 | 0.693545 | 3 | 0 | 3 |
| LMF1 | ADRA2C | 0.693059 | 3 | 0 | 3 |
| LMF1 | GPR52 | 0.685825 | 4 | 0 | 4 |
| LMF1 | CCL27 | 0.6838 | 3 | 0 | 3 |
| LMF1 | MEFV | 0.681194 | 3 | 0 | 3 |
| LMF1 | CEND1 | 0.674505 | 5 | 0 | 4 |
| LMF1 | HAO2 | 0.674187 | 3 | 0 | 3 |
| LMF1 | OR10H3 | 0.672284 | 3 | 0 | 3 |
| LMF1 | FFAR2 | 0.666594 | 3 | 0 | 3 |
| LMF1 | BMF | 0.661742 | 3 | 0 | 3 |
| LMF1 | CALCA | 0.660012 | 4 | 0 | 4 |
For details and further investigation, click here
