| Full name: alcohol dehydrogenase 6 (class V) | Alias Symbol: ADH-5 | ||
| Type: protein-coding gene | Cytoband: 4q23 | ||
| Entrez ID: 130 | HGNC ID: HGNC:255 | Ensembl Gene: ENSG00000172955 | OMIM ID: 103735 |
| Drug and gene relationship at DGIdb | |||
Expression of ADH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADH6 | 130 | 214261_s_at | -0.1682 | 0.3753 | |
| GSE20347 | ADH6 | 130 | 214261_s_at | -0.1747 | 0.0162 | |
| GSE23400 | ADH6 | 130 | 214261_s_at | -0.2334 | 0.0000 | |
| GSE26886 | ADH6 | 130 | 214261_s_at | -0.2728 | 0.0645 | |
| GSE29001 | ADH6 | 130 | 214261_s_at | -0.2356 | 0.1541 | |
| GSE38129 | ADH6 | 130 | 214261_s_at | -0.2658 | 0.0003 | |
| GSE45670 | ADH6 | 130 | 214261_s_at | -0.2782 | 0.0037 | |
| GSE53622 | ADH6 | 130 | 138282 | -0.0020 | 0.9847 | |
| GSE53624 | ADH6 | 130 | 138282 | 0.1469 | 0.0647 | |
| GSE63941 | ADH6 | 130 | 214261_s_at | 0.0167 | 0.9341 | |
| GSE77861 | ADH6 | 130 | 214261_s_at | -0.3975 | 0.0448 | |
| GSE97050 | ADH6 | 130 | A_23_P41498 | -0.1700 | 0.6577 | |
| SRP133303 | ADH6 | 130 | RNAseq | -0.1301 | 0.7488 | |
| SRP159526 | ADH6 | 130 | RNAseq | 0.2826 | 0.6800 | |
| SRP193095 | ADH6 | 130 | RNAseq | -0.9602 | 0.0029 | |
| SRP219564 | ADH6 | 130 | RNAseq | -0.8906 | 0.0529 | |
| TCGA | ADH6 | 130 | RNAseq | -0.6651 | 0.1497 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADH6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADH6 | 130 | 0 | 12 | 18 | |
| GSE20123 | ADH6 | 130 | 0 | 12 | 18 | |
| GSE43470 | ADH6 | 130 | 0 | 14 | 29 | |
| GSE46452 | ADH6 | 130 | 1 | 36 | 22 | |
| GSE47630 | ADH6 | 130 | 0 | 20 | 20 | |
| GSE54993 | ADH6 | 130 | 9 | 0 | 61 | |
| GSE54994 | ADH6 | 130 | 1 | 11 | 41 | |
| GSE60625 | ADH6 | 130 | 0 | 3 | 8 | |
| GSE74703 | ADH6 | 130 | 0 | 12 | 24 | |
| GSE74704 | ADH6 | 130 | 0 | 6 | 14 | |
| TCGA | ADH6 | 130 | 8 | 41 | 47 |
Total number of gains: 19; Total number of losses: 167; Total Number of normals: 302.
Somatic mutations of ADH6:
Generating mutation plots.
Highly correlated genes for ADH6:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADH6 | SPNS3 | 0.765602 | 3 | 0 | 3 |
| ADH6 | POU1F1 | 0.762666 | 3 | 0 | 3 |
| ADH6 | KRTAP2-1 | 0.748787 | 3 | 0 | 3 |
| ADH6 | TSSK3 | 0.743617 | 3 | 0 | 3 |
| ADH6 | GPHA2 | 0.736949 | 3 | 0 | 3 |
| ADH6 | RASL10A | 0.734835 | 3 | 0 | 3 |
| ADH6 | PLA2G12B | 0.732853 | 3 | 0 | 3 |
| ADH6 | ARSE | 0.730392 | 4 | 0 | 4 |
| ADH6 | HBM | 0.7303 | 3 | 0 | 3 |
| ADH6 | DRD2 | 0.729794 | 5 | 0 | 5 |
| ADH6 | OPTC | 0.728985 | 4 | 0 | 4 |
| ADH6 | GABRD | 0.712322 | 5 | 0 | 4 |
| ADH6 | PAX8 | 0.709708 | 8 | 0 | 8 |
| ADH6 | IGLON5 | 0.709252 | 3 | 0 | 3 |
| ADH6 | SCN5A | 0.709135 | 4 | 0 | 3 |
| ADH6 | BTNL2 | 0.708296 | 6 | 0 | 6 |
| ADH6 | TXNDC2 | 0.70644 | 4 | 0 | 4 |
| ADH6 | CLDN9 | 0.706043 | 7 | 0 | 7 |
| ADH6 | CD72 | 0.706007 | 3 | 0 | 3 |
| ADH6 | SLC9A7 | 0.702491 | 3 | 0 | 3 |
For details and further investigation, click here
