Full name: WASP actin nucleation promoting factor	Alias Symbol: WASP|WASPA
Type: protein-coding gene	Cytoband: Xp11.23
Entrez ID: 7454	HGNC ID: HGNC:12731	Ensembl Gene: ENSG00000015285	OMIM ID: 300392
Drug and gene relationship at DGIdb

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WAS involved pathways:

KEGG pathway	Description	View
hsa04062	Chemokine signaling pathway	View
hsa04520	Adherens junction	View
hsa04666	Fc gamma R-mediated phagocytosis	View
hsa04810	Regulation of actin cytoskeleton	View
hsa05100	Bacterial invasion of epithelial cells	View
hsa05130	Pathogenic Escherichia coli infection	View
hsa05132	Salmonella infection	View
hsa05231	Choline metabolism in cancer	View

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Expression of WAS:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	WAS	7454	38964_r_at	0.0822	0.8385	Show
GSE20347	WAS	7454	38964_r_at	-0.0384	0.7560	Show
GSE23400	WAS	7454	38964_r_at	-0.0658	0.0651	Show
GSE26886	WAS	7454	38964_r_at	-0.0995	0.4531	Show
GSE29001	WAS	7454	38964_r_at	-0.1700	0.3595	Show
GSE38129	WAS	7454	38964_r_at	-0.1431	0.1137	Show
GSE45670	WAS	7454	38964_r_at	0.0462	0.6731	Show
GSE53622	WAS	7454	55399	-0.1993	0.0334	Show
GSE53624	WAS	7454	55399	-0.3550	0.0000	Show
GSE63941	WAS	7454	38964_r_at	0.2312	0.1226	Show
GSE77861	WAS	7454	38964_r_at	0.0111	0.9131	Show
GSE97050	WAS	7454	A_23_P96331	0.4293	0.2518	Show
SRP064894	WAS	7454	RNAseq	0.6841	0.0212	Show
SRP133303	WAS	7454	RNAseq	0.1427	0.5914	Show
SRP159526	WAS	7454	RNAseq	-0.6510	0.3183	Show
SRP193095	WAS	7454	RNAseq	0.6785	0.0159	Show
SRP219564	WAS	7454	RNAseq	0.8858	0.0457	Show
TCGA	WAS	7454	RNAseq	0.1327	0.3597	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by WAS expression:

 

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Copy number change of WAS:

 

No record found for this gene.

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Somatic mutations of WAS:

 

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Highly correlated genes for WAS:

 

Showing top 20/627 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
WAS	BMF	0.777234	4	0	4
WAS	SIGLEC8	0.753192	3	0	3
WAS	MYO15B	0.739623	4	0	4
WAS	POU1F1	0.739314	4	0	4
WAS	TNR	0.732504	5	0	5
WAS	CPLX2	0.727619	3	0	3
WAS	CHTF8	0.725313	3	0	3
WAS	PHF7	0.722899	4	0	4
WAS	ZNF221	0.720978	3	0	3
WAS	PTPRCAP	0.717916	9	0	8
WAS	CD48	0.714118	9	0	9
WAS	PTK2B	0.711611	3	0	3
WAS	TSPAN11	0.710592	3	0	3
WAS	TBC1D10C	0.709883	6	0	5
WAS	AKNA	0.708156	7	0	7
WAS	AGRP	0.705438	4	0	3
WAS	ZNF821	0.702695	3	0	3
WAS	CD247	0.699669	9	0	9
WAS	B3GALT1	0.695233	4	0	3
WAS	EVX1	0.693941	4	0	4

For details and further investigation, click here