| Full name: dynein axonemal heavy chain 6 | Alias Symbol: Dnahc6|HL-2|FLJ37357 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 1768 | HGNC ID: HGNC:2951 | Ensembl Gene: ENSG00000115423 | OMIM ID: 603336 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH6 | 1768 | 1561616_a_at | -0.1114 | 0.8094 | |
| GSE20347 | DNAH6 | 1768 | 215341_at | 0.0022 | 0.9866 | |
| GSE23400 | DNAH6 | 1768 | 215341_at | -0.1613 | 0.0005 | |
| GSE26886 | DNAH6 | 1768 | 1561616_a_at | -0.7916 | 0.0010 | |
| GSE29001 | DNAH6 | 1768 | 215341_at | -0.0858 | 0.4839 | |
| GSE38129 | DNAH6 | 1768 | 215341_at | -0.0699 | 0.5789 | |
| GSE45670 | DNAH6 | 1768 | 1561616_a_at | 0.3793 | 0.0017 | |
| GSE53622 | DNAH6 | 1768 | 32957 | 0.1375 | 0.0460 | |
| GSE53624 | DNAH6 | 1768 | 32957 | 0.2225 | 0.0098 | |
| GSE63941 | DNAH6 | 1768 | 1561616_a_at | 0.6017 | 0.0020 | |
| GSE77861 | DNAH6 | 1768 | 1561616_a_at | -0.1469 | 0.1273 | |
| GSE97050 | DNAH6 | 1768 | A_33_P3422947 | 0.1151 | 0.6478 | |
| SRP133303 | DNAH6 | 1768 | RNAseq | -0.3543 | 0.5214 | |
| SRP159526 | DNAH6 | 1768 | RNAseq | 1.2839 | 0.0556 | |
| TCGA | DNAH6 | 1768 | RNAseq | -1.5938 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAH6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH6 | 1768 | 9 | 2 | 19 | |
| GSE20123 | DNAH6 | 1768 | 8 | 2 | 20 | |
| GSE43470 | DNAH6 | 1768 | 4 | 2 | 37 | |
| GSE46452 | DNAH6 | 1768 | 2 | 3 | 54 | |
| GSE47630 | DNAH6 | 1768 | 7 | 0 | 33 | |
| GSE54993 | DNAH6 | 1768 | 0 | 6 | 64 | |
| GSE54994 | DNAH6 | 1768 | 10 | 1 | 42 | |
| GSE60625 | DNAH6 | 1768 | 0 | 3 | 8 | |
| GSE74703 | DNAH6 | 1768 | 4 | 1 | 31 | |
| GSE74704 | DNAH6 | 1768 | 6 | 0 | 14 | |
| TCGA | DNAH6 | 1768 | 36 | 3 | 57 |
Total number of gains: 86; Total number of losses: 23; Total Number of normals: 379.
Somatic mutations of DNAH6:
Generating mutation plots.
Highly correlated genes for DNAH6:
Showing top 20/957 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH6 | NT5C1A | 0.874781 | 3 | 0 | 3 |
| DNAH6 | TMEM37 | 0.806887 | 3 | 0 | 3 |
| DNAH6 | CRB3 | 0.773458 | 3 | 0 | 3 |
| DNAH6 | DDC | 0.765209 | 3 | 0 | 3 |
| DNAH6 | TKTL1 | 0.762059 | 3 | 0 | 3 |
| DNAH6 | WDR87 | 0.753975 | 3 | 0 | 3 |
| DNAH6 | GZMM | 0.749212 | 3 | 0 | 3 |
| DNAH6 | CELF4 | 0.747694 | 3 | 0 | 3 |
| DNAH6 | GALR2 | 0.73955 | 4 | 0 | 4 |
| DNAH6 | AZU1 | 0.738072 | 4 | 0 | 4 |
| DNAH6 | POU1F1 | 0.733066 | 3 | 0 | 3 |
| DNAH6 | PHGR1 | 0.730903 | 3 | 0 | 3 |
| DNAH6 | CCDC42 | 0.723652 | 3 | 0 | 3 |
| DNAH6 | EME2 | 0.717879 | 3 | 0 | 3 |
| DNAH6 | KCNT1 | 0.712419 | 4 | 0 | 3 |
| DNAH6 | ESPNL | 0.711064 | 4 | 0 | 4 |
| DNAH6 | ECHDC3 | 0.708689 | 4 | 0 | 3 |
| DNAH6 | USH1C | 0.705539 | 6 | 0 | 6 |
| DNAH6 | PROCA1 | 0.705002 | 4 | 0 | 4 |
| DNAH6 | AICDA | 0.700855 | 4 | 0 | 4 |
For details and further investigation, click here
