| Full name: glutamate ionotropic receptor delta type subunit 2 | Alias Symbol: GluD2|GluR-delta-2 | ||
| Type: protein-coding gene | Cytoband: 4q22.1-q22.2 | ||
| Entrez ID: 2895 | HGNC ID: HGNC:4576 | Ensembl Gene: ENSG00000152208 | OMIM ID: 602368 |
| Drug and gene relationship at DGIdb | |||
GRID2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04730 | Long-term depression |
Expression of GRID2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRID2 | 2895 | 221364_at | -0.0574 | 0.7994 | |
| GSE20347 | GRID2 | 2895 | 221364_at | -0.1687 | 0.0077 | |
| GSE23400 | GRID2 | 2895 | 221364_at | -0.1716 | 0.0000 | |
| GSE26886 | GRID2 | 2895 | 221364_at | 0.0677 | 0.5230 | |
| GSE29001 | GRID2 | 2895 | 221364_at | -0.2241 | 0.1323 | |
| GSE38129 | GRID2 | 2895 | 221364_at | -0.1936 | 0.0014 | |
| GSE45670 | GRID2 | 2895 | 221364_at | 0.0648 | 0.4486 | |
| GSE53622 | GRID2 | 2895 | 101642 | -0.2401 | 0.0064 | |
| GSE53624 | GRID2 | 2895 | 101642 | -0.1318 | 0.0744 | |
| GSE63941 | GRID2 | 2895 | 221364_at | 0.2380 | 0.0832 | |
| GSE77861 | GRID2 | 2895 | 221364_at | -0.1733 | 0.0642 | |
| GSE97050 | GRID2 | 2895 | A_23_P32847 | -0.1979 | 0.3291 | |
| TCGA | GRID2 | 2895 | RNAseq | -2.0391 | 0.1156 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GRID2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRID2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRID2 | 2895 | 0 | 13 | 17 | |
| GSE20123 | GRID2 | 2895 | 0 | 13 | 17 | |
| GSE43470 | GRID2 | 2895 | 0 | 16 | 27 | |
| GSE46452 | GRID2 | 2895 | 1 | 36 | 22 | |
| GSE47630 | GRID2 | 2895 | 0 | 20 | 20 | |
| GSE54993 | GRID2 | 2895 | 8 | 0 | 62 | |
| GSE54994 | GRID2 | 2895 | 1 | 11 | 41 | |
| GSE60625 | GRID2 | 2895 | 0 | 3 | 8 | |
| GSE74703 | GRID2 | 2895 | 0 | 14 | 22 | |
| GSE74704 | GRID2 | 2895 | 0 | 7 | 13 | |
| TCGA | GRID2 | 2895 | 9 | 39 | 48 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of GRID2:
Generating mutation plots.
Highly correlated genes for GRID2:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRID2 | IFNA4 | 0.772575 | 3 | 0 | 3 |
| GRID2 | HECW1 | 0.771527 | 4 | 0 | 4 |
| GRID2 | LMAN1L | 0.771478 | 5 | 0 | 5 |
| GRID2 | CIB3 | 0.768844 | 3 | 0 | 3 |
| GRID2 | POU1F1 | 0.749909 | 3 | 0 | 3 |
| GRID2 | HSD3B1 | 0.73714 | 3 | 0 | 3 |
| GRID2 | ATP2B2 | 0.729474 | 3 | 0 | 3 |
| GRID2 | ADORA3 | 0.729183 | 3 | 0 | 3 |
| GRID2 | KRTAP2-1 | 0.728734 | 3 | 0 | 3 |
| GRID2 | C1orf61 | 0.727191 | 3 | 0 | 3 |
| GRID2 | GDF7 | 0.722631 | 3 | 0 | 3 |
| GRID2 | KIF6 | 0.716306 | 3 | 0 | 3 |
| GRID2 | FAM163A | 0.714734 | 4 | 0 | 4 |
| GRID2 | GPR150 | 0.713654 | 3 | 0 | 3 |
| GRID2 | EPHA5 | 0.70983 | 3 | 0 | 3 |
| GRID2 | FAM189A1 | 0.705445 | 4 | 0 | 4 |
| GRID2 | KLHL35 | 0.704836 | 4 | 0 | 3 |
| GRID2 | ADM2 | 0.700429 | 6 | 0 | 4 |
| GRID2 | KCNA7 | 0.698779 | 3 | 0 | 3 |
| GRID2 | LCT | 0.695275 | 5 | 0 | 5 |
For details and further investigation, click here
