| Full name: PR/SET domain 2 | Alias Symbol: RIZ|RIZ1|RIZ2|KMT8|MTB-ZF|HUMHOXY1|KMT8A | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 7799 | HGNC ID: HGNC:9347 | Ensembl Gene: ENSG00000116731 | OMIM ID: 601196 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM2 | 7799 | 203057_s_at | -0.3028 | 0.3002 | |
| GSE20347 | PRDM2 | 7799 | 203057_s_at | -0.5560 | 0.0000 | |
| GSE23400 | PRDM2 | 7799 | 203057_s_at | -0.2469 | 0.0006 | |
| GSE26886 | PRDM2 | 7799 | 203057_s_at | -1.1705 | 0.0000 | |
| GSE29001 | PRDM2 | 7799 | 203057_s_at | -0.6119 | 0.0037 | |
| GSE38129 | PRDM2 | 7799 | 203057_s_at | -0.3619 | 0.0148 | |
| GSE45670 | PRDM2 | 7799 | 203057_s_at | -0.1983 | 0.1859 | |
| GSE53622 | PRDM2 | 7799 | 43393 | -0.4485 | 0.0000 | |
| GSE53624 | PRDM2 | 7799 | 43393 | -0.4484 | 0.0000 | |
| GSE63941 | PRDM2 | 7799 | 203057_s_at | -0.3464 | 0.3544 | |
| GSE77861 | PRDM2 | 7799 | 203057_s_at | -0.5576 | 0.0359 | |
| GSE97050 | PRDM2 | 7799 | A_33_P3342076 | -0.3929 | 0.3280 | |
| SRP007169 | PRDM2 | 7799 | RNAseq | -0.7484 | 0.0856 | |
| SRP008496 | PRDM2 | 7799 | RNAseq | -0.5198 | 0.1095 | |
| SRP064894 | PRDM2 | 7799 | RNAseq | -0.5210 | 0.0025 | |
| SRP133303 | PRDM2 | 7799 | RNAseq | -0.1970 | 0.1517 | |
| SRP159526 | PRDM2 | 7799 | RNAseq | -0.5149 | 0.0023 | |
| SRP193095 | PRDM2 | 7799 | RNAseq | -0.4017 | 0.0075 | |
| SRP219564 | PRDM2 | 7799 | RNAseq | -0.5437 | 0.0394 | |
| TCGA | PRDM2 | 7799 | RNAseq | -0.0991 | 0.0310 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRDM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM2 | 7799 | 0 | 4 | 26 | |
| GSE20123 | PRDM2 | 7799 | 0 | 3 | 27 | |
| GSE43470 | PRDM2 | 7799 | 2 | 8 | 33 | |
| GSE46452 | PRDM2 | 7799 | 7 | 1 | 51 | |
| GSE47630 | PRDM2 | 7799 | 8 | 3 | 29 | |
| GSE54993 | PRDM2 | 7799 | 3 | 1 | 66 | |
| GSE54994 | PRDM2 | 7799 | 10 | 4 | 39 | |
| GSE60625 | PRDM2 | 7799 | 0 | 0 | 11 | |
| GSE74703 | PRDM2 | 7799 | 2 | 5 | 29 | |
| GSE74704 | PRDM2 | 7799 | 0 | 0 | 20 | |
| TCGA | PRDM2 | 7799 | 10 | 22 | 64 |
Total number of gains: 42; Total number of losses: 51; Total Number of normals: 395.
Somatic mutations of PRDM2:
Generating mutation plots.
Highly correlated genes for PRDM2:
Showing top 20/1447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM2 | SRP68 | 0.814203 | 3 | 0 | 3 |
| PRDM2 | NKIRAS1 | 0.787266 | 3 | 0 | 3 |
| PRDM2 | LETMD1 | 0.777681 | 3 | 0 | 3 |
| PRDM2 | ZNF416 | 0.763891 | 5 | 0 | 5 |
| PRDM2 | THYN1 | 0.759494 | 3 | 0 | 3 |
| PRDM2 | PANK1 | 0.757342 | 4 | 0 | 4 |
| PRDM2 | RHBDD1 | 0.751923 | 3 | 0 | 3 |
| PRDM2 | ZNF92 | 0.751638 | 3 | 0 | 3 |
| PRDM2 | ZNF398 | 0.749378 | 3 | 0 | 3 |
| PRDM2 | ZNF547 | 0.748763 | 3 | 0 | 3 |
| PRDM2 | UXT | 0.747321 | 3 | 0 | 3 |
| PRDM2 | AKAP17A | 0.747011 | 3 | 0 | 3 |
| PRDM2 | AP3M1 | 0.736587 | 5 | 0 | 4 |
| PRDM2 | PTGR1 | 0.727677 | 3 | 0 | 3 |
| PRDM2 | SLC16A14 | 0.727168 | 3 | 0 | 3 |
| PRDM2 | SOCS6 | 0.723536 | 9 | 0 | 8 |
| PRDM2 | EPG5 | 0.72193 | 6 | 0 | 5 |
| PRDM2 | OS9 | 0.721846 | 4 | 0 | 4 |
| PRDM2 | TMCC1 | 0.720843 | 3 | 0 | 3 |
| PRDM2 | KLHL15 | 0.72069 | 3 | 0 | 3 |
For details and further investigation, click here
