| Full name: NFKB inhibitor interacting Ras like 1 | Alias Symbol: KBRAS1|kappaB-Ras1 | ||
| Type: protein-coding gene | Cytoband: 3p24.2 | ||
| Entrez ID: 28512 | HGNC ID: HGNC:17899 | Ensembl Gene: ENSG00000197885 | OMIM ID: 604496 |
| Drug and gene relationship at DGIdb | |||
Expression of NKIRAS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NKIRAS1 | 28512 | 225930_at | -0.2263 | 0.6019 | |
| GSE26886 | NKIRAS1 | 28512 | 225930_at | -0.6087 | 0.0114 | |
| GSE45670 | NKIRAS1 | 28512 | 225930_at | -0.2290 | 0.0902 | |
| GSE53622 | NKIRAS1 | 28512 | 118796 | -0.6523 | 0.0000 | |
| GSE53624 | NKIRAS1 | 28512 | 118796 | -0.6147 | 0.0000 | |
| GSE63941 | NKIRAS1 | 28512 | 225930_at | -0.8559 | 0.0482 | |
| GSE77861 | NKIRAS1 | 28512 | 225930_at | -0.1982 | 0.3206 | |
| GSE97050 | NKIRAS1 | 28512 | A_23_P338519 | -0.5387 | 0.1920 | |
| SRP007169 | NKIRAS1 | 28512 | RNAseq | -0.9855 | 0.0282 | |
| SRP008496 | NKIRAS1 | 28512 | RNAseq | -1.0003 | 0.0015 | |
| SRP064894 | NKIRAS1 | 28512 | RNAseq | -0.5682 | 0.0000 | |
| SRP133303 | NKIRAS1 | 28512 | RNAseq | -0.2107 | 0.1996 | |
| SRP159526 | NKIRAS1 | 28512 | RNAseq | -0.1145 | 0.6918 | |
| SRP193095 | NKIRAS1 | 28512 | RNAseq | -0.4209 | 0.0002 | |
| SRP219564 | NKIRAS1 | 28512 | RNAseq | -0.4860 | 0.2335 | |
| TCGA | NKIRAS1 | 28512 | RNAseq | -0.1896 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NKIRAS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NKIRAS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NKIRAS1 | 28512 | 0 | 18 | 12 | |
| GSE20123 | NKIRAS1 | 28512 | 0 | 18 | 12 | |
| GSE43470 | NKIRAS1 | 28512 | 0 | 20 | 23 | |
| GSE46452 | NKIRAS1 | 28512 | 2 | 17 | 40 | |
| GSE47630 | NKIRAS1 | 28512 | 1 | 24 | 15 | |
| GSE54993 | NKIRAS1 | 28512 | 6 | 2 | 62 | |
| GSE54994 | NKIRAS1 | 28512 | 1 | 32 | 20 | |
| GSE60625 | NKIRAS1 | 28512 | 5 | 0 | 6 | |
| GSE74703 | NKIRAS1 | 28512 | 0 | 17 | 19 | |
| GSE74704 | NKIRAS1 | 28512 | 0 | 12 | 8 | |
| TCGA | NKIRAS1 | 28512 | 0 | 69 | 27 |
Total number of gains: 15; Total number of losses: 229; Total Number of normals: 244.
Somatic mutations of NKIRAS1:
Generating mutation plots.
Highly correlated genes for NKIRAS1:
Showing top 20/748 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NKIRAS1 | PRDM2 | 0.787266 | 3 | 0 | 3 |
| NKIRAS1 | WBP4 | 0.782327 | 3 | 0 | 3 |
| NKIRAS1 | HAGH | 0.773604 | 3 | 0 | 3 |
| NKIRAS1 | TBC1D19 | 0.760262 | 3 | 0 | 3 |
| NKIRAS1 | CCNYL1 | 0.758579 | 3 | 0 | 3 |
| NKIRAS1 | ILK | 0.749066 | 3 | 0 | 3 |
| NKIRAS1 | KIF5B | 0.746745 | 3 | 0 | 3 |
| NKIRAS1 | HBP1 | 0.743356 | 3 | 0 | 3 |
| NKIRAS1 | ESYT2 | 0.73947 | 3 | 0 | 3 |
| NKIRAS1 | ANGPTL7 | 0.738326 | 3 | 0 | 3 |
| NKIRAS1 | RASSF3 | 0.735791 | 3 | 0 | 3 |
| NKIRAS1 | NDUFB8 | 0.732681 | 3 | 0 | 3 |
| NKIRAS1 | UBP1 | 0.729338 | 3 | 0 | 3 |
| NKIRAS1 | C21orf91 | 0.727383 | 3 | 0 | 3 |
| NKIRAS1 | FAHD1 | 0.727281 | 3 | 0 | 3 |
| NKIRAS1 | NFASC | 0.722938 | 4 | 0 | 4 |
| NKIRAS1 | AKAP6 | 0.714792 | 4 | 0 | 3 |
| NKIRAS1 | CEP112 | 0.710686 | 4 | 0 | 3 |
| NKIRAS1 | PFDN5 | 0.710131 | 3 | 0 | 3 |
| NKIRAS1 | ST6GALNAC6 | 0.709892 | 3 | 0 | 3 |
For details and further investigation, click here
