| Full name: LETM1 domain containing 1 | Alias Symbol: HCCR1|HCCR|HCCR-2|HCCR-1|HCCR2|SLC55A3 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 25875 | HGNC ID: HGNC:24241 | Ensembl Gene: ENSG00000050426 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LETMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LETMD1 | 25875 | 207170_s_at | -0.5507 | 0.2525 | |
| GSE20347 | LETMD1 | 25875 | 207170_s_at | 0.1211 | 0.2907 | |
| GSE23400 | LETMD1 | 25875 | 207170_s_at | 0.0139 | 0.8000 | |
| GSE26886 | LETMD1 | 25875 | 207170_s_at | -0.5979 | 0.0270 | |
| GSE29001 | LETMD1 | 25875 | 207170_s_at | -0.1507 | 0.6112 | |
| GSE38129 | LETMD1 | 25875 | 207170_s_at | -0.0891 | 0.4366 | |
| GSE45670 | LETMD1 | 25875 | 207170_s_at | -0.4108 | 0.0000 | |
| GSE53622 | LETMD1 | 25875 | 93681 | -0.3817 | 0.0000 | |
| GSE53624 | LETMD1 | 25875 | 93681 | -0.1088 | 0.1460 | |
| GSE63941 | LETMD1 | 25875 | 207170_s_at | 0.6179 | 0.2215 | |
| GSE77861 | LETMD1 | 25875 | 207170_s_at | 0.0446 | 0.8945 | |
| GSE97050 | LETMD1 | 25875 | A_23_P117037 | -0.1598 | 0.4861 | |
| SRP007169 | LETMD1 | 25875 | RNAseq | 0.5519 | 0.1521 | |
| SRP008496 | LETMD1 | 25875 | RNAseq | 0.5000 | 0.1180 | |
| SRP064894 | LETMD1 | 25875 | RNAseq | -0.1249 | 0.4973 | |
| SRP133303 | LETMD1 | 25875 | RNAseq | -0.0248 | 0.9153 | |
| SRP159526 | LETMD1 | 25875 | RNAseq | -0.2014 | 0.4901 | |
| SRP193095 | LETMD1 | 25875 | RNAseq | -0.3168 | 0.0021 | |
| SRP219564 | LETMD1 | 25875 | RNAseq | -0.0945 | 0.7658 | |
| TCGA | LETMD1 | 25875 | RNAseq | -0.2255 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LETMD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LETMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LETMD1 | 25875 | 8 | 1 | 21 | |
| GSE20123 | LETMD1 | 25875 | 8 | 1 | 21 | |
| GSE43470 | LETMD1 | 25875 | 3 | 0 | 40 | |
| GSE46452 | LETMD1 | 25875 | 8 | 1 | 50 | |
| GSE47630 | LETMD1 | 25875 | 11 | 2 | 27 | |
| GSE54993 | LETMD1 | 25875 | 0 | 5 | 65 | |
| GSE54994 | LETMD1 | 25875 | 3 | 2 | 48 | |
| GSE60625 | LETMD1 | 25875 | 0 | 0 | 11 | |
| GSE74703 | LETMD1 | 25875 | 3 | 0 | 33 | |
| GSE74704 | LETMD1 | 25875 | 5 | 1 | 14 | |
| TCGA | LETMD1 | 25875 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 24; Total Number of normals: 402.
Somatic mutations of LETMD1:
Generating mutation plots.
Highly correlated genes for LETMD1:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LETMD1 | GNAQ | 0.797239 | 3 | 0 | 3 |
| LETMD1 | PRDM2 | 0.777681 | 3 | 0 | 3 |
| LETMD1 | C5orf51 | 0.775747 | 3 | 0 | 3 |
| LETMD1 | PEG3 | 0.77119 | 3 | 0 | 3 |
| LETMD1 | FBXL3 | 0.754252 | 4 | 0 | 4 |
| LETMD1 | IGF1 | 0.753227 | 3 | 0 | 3 |
| LETMD1 | RTN3 | 0.752311 | 3 | 0 | 3 |
| LETMD1 | PPP1R8 | 0.751464 | 3 | 0 | 3 |
| LETMD1 | SMARCAD1 | 0.749302 | 3 | 0 | 3 |
| LETMD1 | KRAS | 0.740568 | 3 | 0 | 3 |
| LETMD1 | NUPR1 | 0.736582 | 3 | 0 | 3 |
| LETMD1 | SP1 | 0.732275 | 5 | 0 | 5 |
| LETMD1 | SLC30A9 | 0.730668 | 3 | 0 | 3 |
| LETMD1 | ICA1L | 0.725779 | 3 | 0 | 3 |
| LETMD1 | RERG | 0.724192 | 4 | 0 | 3 |
| LETMD1 | RPL41 | 0.719334 | 5 | 0 | 5 |
| LETMD1 | DLD | 0.719079 | 4 | 0 | 3 |
| LETMD1 | ZNF175 | 0.718574 | 3 | 0 | 3 |
| LETMD1 | PITHD1 | 0.718552 | 3 | 0 | 3 |
| LETMD1 | RPL14 | 0.718214 | 4 | 0 | 4 |
For details and further investigation, click here
