| Full name: transmembrane and coiled-coil domain family 1 | Alias Symbol: KIAA0779 | ||
| Type: protein-coding gene | Cytoband: 3q22.1 | ||
| Entrez ID: 23023 | HGNC ID: HGNC:29116 | Ensembl Gene: ENSG00000172765 | OMIM ID: 616242 |
| Drug and gene relationship at DGIdb | |||
Expression of TMCC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMCC1 | 23023 | 227112_at | -0.1647 | 0.5921 | |
| GSE20347 | TMCC1 | 23023 | 213349_at | -0.2831 | 0.0922 | |
| GSE23400 | TMCC1 | 23023 | 213349_at | -0.0825 | 0.3860 | |
| GSE26886 | TMCC1 | 23023 | 227112_at | -0.1640 | 0.5269 | |
| GSE29001 | TMCC1 | 23023 | 213351_s_at | 0.1984 | 0.3998 | |
| GSE38129 | TMCC1 | 23023 | 213351_s_at | -0.0541 | 0.6867 | |
| GSE45670 | TMCC1 | 23023 | 213349_at | 0.2105 | 0.2441 | |
| GSE53622 | TMCC1 | 23023 | 121012 | -0.1606 | 0.0613 | |
| GSE53624 | TMCC1 | 23023 | 121012 | -0.2367 | 0.0399 | |
| GSE63941 | TMCC1 | 23023 | 227112_at | -0.1435 | 0.7411 | |
| GSE77861 | TMCC1 | 23023 | 213349_at | -0.2940 | 0.3249 | |
| GSE97050 | TMCC1 | 23023 | A_32_P41065 | -0.1126 | 0.6391 | |
| SRP007169 | TMCC1 | 23023 | RNAseq | -0.5243 | 0.1175 | |
| SRP008496 | TMCC1 | 23023 | RNAseq | -0.1905 | 0.4890 | |
| SRP064894 | TMCC1 | 23023 | RNAseq | -0.0874 | 0.6241 | |
| SRP133303 | TMCC1 | 23023 | RNAseq | 0.1629 | 0.3084 | |
| SRP159526 | TMCC1 | 23023 | RNAseq | -0.2884 | 0.2426 | |
| SRP193095 | TMCC1 | 23023 | RNAseq | -0.0533 | 0.6970 | |
| SRP219564 | TMCC1 | 23023 | RNAseq | -0.4020 | 0.1818 | |
| TCGA | TMCC1 | 23023 | RNAseq | 0.1953 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMCC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMCC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMCC1 | 23023 | 17 | 0 | 13 | |
| GSE20123 | TMCC1 | 23023 | 17 | 0 | 13 | |
| GSE43470 | TMCC1 | 23023 | 19 | 0 | 24 | |
| GSE46452 | TMCC1 | 23023 | 14 | 5 | 40 | |
| GSE47630 | TMCC1 | 23023 | 18 | 3 | 19 | |
| GSE54993 | TMCC1 | 23023 | 2 | 8 | 60 | |
| GSE54994 | TMCC1 | 23023 | 32 | 3 | 18 | |
| GSE60625 | TMCC1 | 23023 | 0 | 6 | 5 | |
| GSE74703 | TMCC1 | 23023 | 17 | 0 | 19 | |
| GSE74704 | TMCC1 | 23023 | 13 | 0 | 7 | |
| TCGA | TMCC1 | 23023 | 59 | 5 | 32 |
Total number of gains: 208; Total number of losses: 30; Total Number of normals: 250.
Somatic mutations of TMCC1:
Generating mutation plots.
Highly correlated genes for TMCC1:
Showing top 20/236 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMCC1 | COG1 | 0.790529 | 3 | 0 | 3 |
| TMCC1 | ST3GAL6 | 0.78739 | 3 | 0 | 3 |
| TMCC1 | VPS29 | 0.771213 | 3 | 0 | 3 |
| TMCC1 | USP8 | 0.766002 | 3 | 0 | 3 |
| TMCC1 | PPM1L | 0.735686 | 3 | 0 | 3 |
| TMCC1 | PRDM2 | 0.720843 | 3 | 0 | 3 |
| TMCC1 | TMEM120A | 0.718911 | 3 | 0 | 3 |
| TMCC1 | ADCY7 | 0.716704 | 3 | 0 | 3 |
| TMCC1 | CTCF | 0.700056 | 3 | 0 | 3 |
| TMCC1 | PANK1 | 0.698334 | 3 | 0 | 3 |
| TMCC1 | ABR | 0.693715 | 3 | 0 | 3 |
| TMCC1 | TMEM220 | 0.687046 | 3 | 0 | 3 |
| TMCC1 | DCTN3 | 0.685055 | 4 | 0 | 3 |
| TMCC1 | YPEL3 | 0.684234 | 3 | 0 | 3 |
| TMCC1 | ZRANB1 | 0.680569 | 4 | 0 | 4 |
| TMCC1 | USP32 | 0.678716 | 3 | 0 | 3 |
| TMCC1 | C6orf120 | 0.678036 | 4 | 0 | 3 |
| TMCC1 | CNPPD1 | 0.676129 | 3 | 0 | 3 |
| TMCC1 | AMBRA1 | 0.674095 | 3 | 0 | 3 |
| TMCC1 | ALKBH7 | 0.671775 | 4 | 0 | 3 |
For details and further investigation, click here
