| Full name: rhomboid domain containing 1 | Alias Symbol: DKFZp547E052 | ||
| Type: protein-coding gene | Cytoband: 2q36.3 | ||
| Entrez ID: 84236 | HGNC ID: HGNC:23081 | Ensembl Gene: ENSG00000144468 | OMIM ID: 617515 |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDD1 | 84236 | 226945_at | -0.1846 | 0.5762 | |
| GSE26886 | RHBDD1 | 84236 | 227414_at | -0.7288 | 0.0003 | |
| GSE45670 | RHBDD1 | 84236 | 226945_at | 0.4324 | 0.0018 | |
| GSE53622 | RHBDD1 | 84236 | 21185 | 0.0166 | 0.8478 | |
| GSE53624 | RHBDD1 | 84236 | 21185 | 0.2343 | 0.0000 | |
| GSE63941 | RHBDD1 | 84236 | 226945_at | -0.0162 | 0.9678 | |
| GSE77861 | RHBDD1 | 84236 | 226945_at | 0.1279 | 0.3780 | |
| GSE97050 | RHBDD1 | 84236 | A_24_P134834 | 0.0829 | 0.8257 | |
| SRP007169 | RHBDD1 | 84236 | RNAseq | -0.3065 | 0.4346 | |
| SRP008496 | RHBDD1 | 84236 | RNAseq | -0.0870 | 0.7798 | |
| SRP064894 | RHBDD1 | 84236 | RNAseq | 0.0780 | 0.4685 | |
| SRP133303 | RHBDD1 | 84236 | RNAseq | -0.0019 | 0.9854 | |
| SRP159526 | RHBDD1 | 84236 | RNAseq | -0.3674 | 0.2280 | |
| SRP193095 | RHBDD1 | 84236 | RNAseq | -0.1741 | 0.0639 | |
| SRP219564 | RHBDD1 | 84236 | RNAseq | 0.0277 | 0.9449 | |
| TCGA | RHBDD1 | 84236 | RNAseq | -0.1368 | 0.0561 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RHBDD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDD1 | 84236 | 2 | 12 | 16 | |
| GSE20123 | RHBDD1 | 84236 | 2 | 12 | 16 | |
| GSE43470 | RHBDD1 | 84236 | 0 | 7 | 36 | |
| GSE46452 | RHBDD1 | 84236 | 0 | 5 | 54 | |
| GSE47630 | RHBDD1 | 84236 | 4 | 5 | 31 | |
| GSE54993 | RHBDD1 | 84236 | 1 | 2 | 67 | |
| GSE54994 | RHBDD1 | 84236 | 6 | 11 | 36 | |
| GSE60625 | RHBDD1 | 84236 | 0 | 3 | 8 | |
| GSE74703 | RHBDD1 | 84236 | 0 | 6 | 30 | |
| GSE74704 | RHBDD1 | 84236 | 2 | 6 | 12 | |
| TCGA | RHBDD1 | 84236 | 13 | 26 | 57 |
Total number of gains: 30; Total number of losses: 95; Total Number of normals: 363.
Somatic mutations of RHBDD1:
Generating mutation plots.
Highly correlated genes for RHBDD1:
Showing top 20/180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDD1 | GLUD1 | 0.832829 | 3 | 0 | 3 |
| RHBDD1 | VAMP3 | 0.821962 | 3 | 0 | 3 |
| RHBDD1 | LTN1 | 0.81678 | 3 | 0 | 3 |
| RHBDD1 | ASB8 | 0.816177 | 3 | 0 | 3 |
| RHBDD1 | KIAA0556 | 0.802996 | 3 | 0 | 3 |
| RHBDD1 | HMGCL | 0.798155 | 3 | 0 | 3 |
| RHBDD1 | ACTR1A | 0.797524 | 3 | 0 | 3 |
| RHBDD1 | PRDM15 | 0.792328 | 3 | 0 | 3 |
| RHBDD1 | VPS26A | 0.792184 | 3 | 0 | 3 |
| RHBDD1 | RNLS | 0.789988 | 3 | 0 | 3 |
| RHBDD1 | RAC1 | 0.787159 | 3 | 0 | 3 |
| RHBDD1 | UBE2G2 | 0.783824 | 3 | 0 | 3 |
| RHBDD1 | UBR2 | 0.777237 | 3 | 0 | 3 |
| RHBDD1 | TRAPPC2 | 0.773763 | 3 | 0 | 3 |
| RHBDD1 | SLC25A14 | 0.768558 | 3 | 0 | 3 |
| RHBDD1 | BARD1 | 0.767825 | 3 | 0 | 3 |
| RHBDD1 | PPP2CB | 0.764047 | 3 | 0 | 3 |
| RHBDD1 | LMBRD2 | 0.7606 | 3 | 0 | 3 |
| RHBDD1 | AP3M1 | 0.760581 | 3 | 0 | 3 |
| RHBDD1 | PRMT2 | 0.758669 | 3 | 0 | 3 |
For details and further investigation, click here
