| Full name: PR/SET domain 9 | Alias Symbol: PFM6|ZNF899|KMT8B | ||
| Type: protein-coding gene | Cytoband: 5p14.2 | ||
| Entrez ID: 56979 | HGNC ID: HGNC:13994 | Ensembl Gene: ENSG00000164256 | OMIM ID: 609760 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM9 | 56979 | 221151_at | -0.0743 | 0.7460 | |
| GSE20347 | PRDM9 | 56979 | 221151_at | 0.0165 | 0.7913 | |
| GSE23400 | PRDM9 | 56979 | 221151_at | -0.0359 | 0.1003 | |
| GSE26886 | PRDM9 | 56979 | 221151_at | -0.0778 | 0.4583 | |
| GSE29001 | PRDM9 | 56979 | 221151_at | -0.0784 | 0.5251 | |
| GSE38129 | PRDM9 | 56979 | 221151_at | -0.0435 | 0.4262 | |
| GSE45670 | PRDM9 | 56979 | 221151_at | -0.0166 | 0.8620 | |
| GSE53622 | PRDM9 | 56979 | 29830 | 0.4109 | 0.0011 | |
| GSE53624 | PRDM9 | 56979 | 29830 | 0.2236 | 0.3713 | |
| GSE63941 | PRDM9 | 56979 | 221151_at | 0.1531 | 0.2543 | |
| GSE77861 | PRDM9 | 56979 | 221151_at | -0.0386 | 0.7485 | |
| SRP133303 | PRDM9 | 56979 | RNAseq | -1.7514 | 0.0000 | |
| TCGA | PRDM9 | 56979 | RNAseq | 3.2492 | 0.0398 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PRDM9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM9 | 56979 | 8 | 0 | 22 | |
| GSE20123 | PRDM9 | 56979 | 8 | 0 | 22 | |
| GSE43470 | PRDM9 | 56979 | 16 | 1 | 26 | |
| GSE46452 | PRDM9 | 56979 | 6 | 21 | 32 | |
| GSE47630 | PRDM9 | 56979 | 6 | 11 | 23 | |
| GSE54993 | PRDM9 | 56979 | 5 | 4 | 61 | |
| GSE54994 | PRDM9 | 56979 | 26 | 2 | 25 | |
| GSE60625 | PRDM9 | 56979 | 0 | 0 | 11 | |
| GSE74703 | PRDM9 | 56979 | 12 | 1 | 23 | |
| GSE74704 | PRDM9 | 56979 | 7 | 0 | 13 | |
| TCGA | PRDM9 | 56979 | 55 | 3 | 38 |
Total number of gains: 149; Total number of losses: 43; Total Number of normals: 296.
Somatic mutations of PRDM9:
Generating mutation plots.
Highly correlated genes for PRDM9:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM9 | FUT9 | 0.657456 | 3 | 0 | 3 |
| PRDM9 | BMP15 | 0.648047 | 5 | 0 | 5 |
| PRDM9 | MAGEC1 | 0.644776 | 3 | 0 | 3 |
| PRDM9 | TAS2R3 | 0.640313 | 3 | 0 | 3 |
| PRDM9 | LRFN4 | 0.638224 | 4 | 0 | 3 |
| PRDM9 | INSL5 | 0.636647 | 4 | 0 | 4 |
| PRDM9 | MYOD1 | 0.632628 | 4 | 0 | 3 |
| PRDM9 | MYT1L | 0.631278 | 3 | 0 | 3 |
| PRDM9 | CCDC30 | 0.629991 | 4 | 0 | 4 |
| PRDM9 | ZNF771 | 0.628305 | 3 | 0 | 3 |
| PRDM9 | SPATA21 | 0.62683 | 3 | 0 | 3 |
| PRDM9 | ALPI | 0.62681 | 4 | 0 | 4 |
| PRDM9 | PRKAR1B | 0.626031 | 5 | 0 | 4 |
| PRDM9 | SCTR | 0.625199 | 5 | 0 | 5 |
| PRDM9 | MAGEA8 | 0.622878 | 3 | 0 | 3 |
| PRDM9 | TRH | 0.622643 | 4 | 0 | 3 |
| PRDM9 | RNF207 | 0.62131 | 3 | 0 | 3 |
| PRDM9 | LINC01366 | 0.618892 | 3 | 0 | 3 |
| PRDM9 | C9orf116 | 0.616667 | 4 | 0 | 4 |
| PRDM9 | FMR1NB | 0.615914 | 3 | 0 | 3 |
For details and further investigation, click here
