| Full name: myelin transcription factor 1 like | Alias Symbol: KIAA1106|NZF1|ZC2HC4B|ZC2H2C2 | ||
| Type: protein-coding gene | Cytoband: 2p25.3 | ||
| Entrez ID: 23040 | HGNC ID: HGNC:7623 | Ensembl Gene: ENSG00000186487 | OMIM ID: 613084 |
| Drug and gene relationship at DGIdb | |||
Expression of MYT1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYT1L | 23040 | 1554633_a_at | 0.0065 | 0.9868 | |
| GSE20347 | MYT1L | 23040 | 210016_at | -0.0826 | 0.1133 | |
| GSE23400 | MYT1L | 23040 | 210016_at | -0.0565 | 0.0124 | |
| GSE26886 | MYT1L | 23040 | 1554633_a_at | -0.1076 | 0.2815 | |
| GSE29001 | MYT1L | 23040 | 210016_at | -0.0004 | 0.9977 | |
| GSE38129 | MYT1L | 23040 | 210016_at | -0.0949 | 0.0326 | |
| GSE45670 | MYT1L | 23040 | 210016_at | 0.1145 | 0.1322 | |
| GSE53622 | MYT1L | 23040 | 28413 | 0.2891 | 0.0051 | |
| GSE53624 | MYT1L | 23040 | 28460 | 0.5390 | 0.0305 | |
| GSE63941 | MYT1L | 23040 | 210016_at | 0.0192 | 0.9002 | |
| GSE77861 | MYT1L | 23040 | 1554633_a_at | -0.0442 | 0.7139 | |
| TCGA | MYT1L | 23040 | RNAseq | -3.6668 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MYT1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYT1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYT1L | 23040 | 8 | 3 | 19 | |
| GSE20123 | MYT1L | 23040 | 8 | 3 | 19 | |
| GSE43470 | MYT1L | 23040 | 3 | 1 | 39 | |
| GSE46452 | MYT1L | 23040 | 3 | 4 | 52 | |
| GSE47630 | MYT1L | 23040 | 7 | 0 | 33 | |
| GSE54993 | MYT1L | 23040 | 1 | 7 | 62 | |
| GSE54994 | MYT1L | 23040 | 13 | 0 | 40 | |
| GSE60625 | MYT1L | 23040 | 0 | 3 | 8 | |
| GSE74703 | MYT1L | 23040 | 3 | 0 | 33 | |
| GSE74704 | MYT1L | 23040 | 8 | 1 | 11 | |
| TCGA | MYT1L | 23040 | 32 | 5 | 59 |
Total number of gains: 86; Total number of losses: 27; Total Number of normals: 375.
Somatic mutations of MYT1L:
Generating mutation plots.
Highly correlated genes for MYT1L:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYT1L | RBFADN | 0.764677 | 3 | 0 | 3 |
| MYT1L | SCGN | 0.726831 | 3 | 0 | 3 |
| MYT1L | FBXO40 | 0.70937 | 3 | 0 | 3 |
| MYT1L | GDNF | 0.692946 | 3 | 0 | 3 |
| MYT1L | IAPP | 0.682532 | 4 | 0 | 4 |
| MYT1L | OR1F1 | 0.681799 | 3 | 0 | 3 |
| MYT1L | ACVR2B-AS1 | 0.676746 | 3 | 0 | 3 |
| MYT1L | SYN1 | 0.675734 | 3 | 0 | 3 |
| MYT1L | CDH10 | 0.67535 | 3 | 0 | 3 |
| MYT1L | CHRM5 | 0.670499 | 3 | 0 | 3 |
| MYT1L | CYP19A1 | 0.667001 | 3 | 0 | 3 |
| MYT1L | MS4A12 | 0.660032 | 4 | 0 | 3 |
| MYT1L | GPR88 | 0.658385 | 3 | 0 | 3 |
| MYT1L | COLEC10 | 0.656765 | 3 | 0 | 3 |
| MYT1L | C1orf68 | 0.655342 | 4 | 0 | 3 |
| MYT1L | LINC01260 | 0.653197 | 3 | 0 | 3 |
| MYT1L | CITED1 | 0.649133 | 3 | 0 | 3 |
| MYT1L | COL4A3 | 0.647381 | 4 | 0 | 3 |
| MYT1L | OR2B2 | 0.64623 | 3 | 0 | 3 |
| MYT1L | ANKRD53 | 0.644499 | 3 | 0 | 3 |
For details and further investigation, click here
