Full name: protein kinase cAMP-dependent type I regulatory subunit beta | Alias Symbol: | ||
Type: protein-coding gene | Cytoband: 7p22.3 | ||
Entrez ID: 5575 | HGNC ID: HGNC:9390 | Ensembl Gene: ENSG00000188191 | OMIM ID: 176911 |
Drug and gene relationship at DGIdb |
PRKAR1B involved pathways:
KEGG pathway | Description | View |
---|---|---|
hsa04910 | Insulin signaling pathway |
Expression of PRKAR1B:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | PRKAR1B | 5575 | 212559_at | 0.5451 | 0.1853 | |
GSE20347 | PRKAR1B | 5575 | 212555_at | 0.0631 | 0.3393 | |
GSE23400 | PRKAR1B | 5575 | 212555_at | 0.0438 | 0.2406 | |
GSE26886 | PRKAR1B | 5575 | 212555_at | 0.0997 | 0.5772 | |
GSE29001 | PRKAR1B | 5575 | 212555_at | -0.0645 | 0.6946 | |
GSE38129 | PRKAR1B | 5575 | 212555_at | 0.0796 | 0.2569 | |
GSE45670 | PRKAR1B | 5575 | 212555_at | 0.1303 | 0.1703 | |
GSE53622 | PRKAR1B | 5575 | 46560 | 0.0616 | 0.2742 | |
GSE53624 | PRKAR1B | 5575 | 46560 | -0.3317 | 0.0073 | |
GSE63941 | PRKAR1B | 5575 | 212555_at | 0.7628 | 0.0110 | |
GSE77861 | PRKAR1B | 5575 | 212555_at | 0.0199 | 0.8577 | |
GSE97050 | PRKAR1B | 5575 | A_23_P83599 | 0.0223 | 0.9421 | |
SRP007169 | PRKAR1B | 5575 | RNAseq | 0.7571 | 0.1715 | |
SRP008496 | PRKAR1B | 5575 | RNAseq | 1.4088 | 0.0023 | |
SRP064894 | PRKAR1B | 5575 | RNAseq | 0.9804 | 0.0024 | |
SRP133303 | PRKAR1B | 5575 | RNAseq | 0.6916 | 0.0043 | |
SRP159526 | PRKAR1B | 5575 | RNAseq | 0.7881 | 0.1539 | |
SRP193095 | PRKAR1B | 5575 | RNAseq | 0.6036 | 0.0002 | |
SRP219564 | PRKAR1B | 5575 | RNAseq | 0.5253 | 0.3634 | |
TCGA | PRKAR1B | 5575 | RNAseq | 0.0985 | 0.3054 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRKAR1B expression:
Note: Click image to view full size file.
Copy number change of PRKAR1B:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | PRKAR1B | 5575 | 14 | 0 | 16 | |
GSE20123 | PRKAR1B | 5575 | 14 | 0 | 16 | |
GSE43470 | PRKAR1B | 5575 | 6 | 2 | 35 | |
GSE46452 | PRKAR1B | 5575 | 13 | 1 | 45 | |
GSE47630 | PRKAR1B | 5575 | 12 | 1 | 27 | |
GSE54993 | PRKAR1B | 5575 | 3 | 10 | 57 | |
GSE54994 | PRKAR1B | 5575 | 20 | 3 | 30 | |
GSE60625 | PRKAR1B | 5575 | 0 | 0 | 11 | |
GSE74703 | PRKAR1B | 5575 | 6 | 1 | 29 | |
GSE74704 | PRKAR1B | 5575 | 9 | 0 | 11 | |
TCGA | PRKAR1B | 5575 | 56 | 6 | 34 |
Total number of gains: 153; Total number of losses: 24; Total Number of normals: 311.
Somatic mutations of PRKAR1B:
Generating mutation plots.
Highly correlated genes for PRKAR1B:
Showing top 20/555 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
PRKAR1B | VIPR2 | 0.813395 | 3 | 0 | 3 |
PRKAR1B | SEC14L4 | 0.795989 | 3 | 0 | 3 |
PRKAR1B | MUC8 | 0.785659 | 4 | 0 | 4 |
PRKAR1B | CCDC142 | 0.783529 | 3 | 0 | 3 |
PRKAR1B | PGC | 0.772999 | 3 | 0 | 3 |
PRKAR1B | C4BPA | 0.75783 | 3 | 0 | 3 |
PRKAR1B | FOLR3 | 0.757155 | 3 | 0 | 3 |
PRKAR1B | NEUROG1 | 0.755529 | 3 | 0 | 3 |
PRKAR1B | NPY2R | 0.754479 | 3 | 0 | 3 |
PRKAR1B | HGD | 0.751031 | 3 | 0 | 3 |
PRKAR1B | PRODH2 | 0.750323 | 4 | 0 | 3 |
PRKAR1B | DCDC1 | 0.750163 | 3 | 0 | 3 |
PRKAR1B | CPNE6 | 0.736088 | 4 | 0 | 4 |
PRKAR1B | CLTCL1 | 0.732822 | 4 | 0 | 4 |
PRKAR1B | DNAI1 | 0.730278 | 4 | 0 | 4 |
PRKAR1B | LILRA1 | 0.729384 | 3 | 0 | 3 |
PRKAR1B | C2CD4D | 0.724234 | 3 | 0 | 3 |
PRKAR1B | MARVELD3 | 0.723895 | 3 | 0 | 3 |
PRKAR1B | SPTBN5 | 0.719789 | 3 | 0 | 3 |
PRKAR1B | IGHMBP2 | 0.717353 | 4 | 0 | 3 |
For details and further investigation, click here