| Full name: chromosome 9 open reading frame 116 | Alias Symbol: MGC29761|RbEST47|PIERCE1 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 138162 | HGNC ID: HGNC:28435 | Ensembl Gene: ENSG00000160345 | OMIM ID: 614502 |
| Drug and gene relationship at DGIdb | |||
Expression of C9orf116:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C9orf116 | 138162 | 221946_at | 0.2927 | 0.4476 | |
| GSE20347 | C9orf116 | 138162 | 221946_at | -0.0764 | 0.2782 | |
| GSE23400 | C9orf116 | 138162 | 221946_at | -0.0883 | 0.0078 | |
| GSE26886 | C9orf116 | 138162 | 221946_at | 0.3069 | 0.0092 | |
| GSE29001 | C9orf116 | 138162 | 221946_at | -0.2212 | 0.0312 | |
| GSE38129 | C9orf116 | 138162 | 221946_at | -0.0364 | 0.7446 | |
| GSE45670 | C9orf116 | 138162 | 221946_at | 0.0568 | 0.7490 | |
| GSE53622 | C9orf116 | 138162 | 48828 | -0.1295 | 0.1244 | |
| GSE53624 | C9orf116 | 138162 | 48828 | -0.1509 | 0.1497 | |
| GSE63941 | C9orf116 | 138162 | 221946_at | 0.4263 | 0.5165 | |
| GSE77861 | C9orf116 | 138162 | 221946_at | -0.1202 | 0.3251 | |
| GSE97050 | C9orf116 | 138162 | A_23_P422115 | 0.1270 | 0.5378 | |
| SRP159526 | C9orf116 | 138162 | RNAseq | 0.9931 | 0.1077 | |
| TCGA | C9orf116 | 138162 | RNAseq | 0.1454 | 0.5207 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C9orf116 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C9orf116:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C9orf116 | 138162 | 4 | 7 | 19 | |
| GSE20123 | C9orf116 | 138162 | 4 | 7 | 19 | |
| GSE43470 | C9orf116 | 138162 | 3 | 7 | 33 | |
| GSE46452 | C9orf116 | 138162 | 6 | 13 | 40 | |
| GSE47630 | C9orf116 | 138162 | 6 | 15 | 19 | |
| GSE54993 | C9orf116 | 138162 | 3 | 3 | 64 | |
| GSE54994 | C9orf116 | 138162 | 11 | 9 | 33 | |
| GSE60625 | C9orf116 | 138162 | 0 | 0 | 11 | |
| GSE74703 | C9orf116 | 138162 | 3 | 5 | 28 | |
| GSE74704 | C9orf116 | 138162 | 2 | 5 | 13 | |
| TCGA | C9orf116 | 138162 | 28 | 25 | 43 |
Total number of gains: 70; Total number of losses: 96; Total Number of normals: 322.
Somatic mutations of C9orf116:
Generating mutation plots.
Highly correlated genes for C9orf116:
Showing top 20/396 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C9orf116 | SUSD3 | 0.753006 | 3 | 0 | 3 |
| C9orf116 | ARHGAP39 | 0.73389 | 3 | 0 | 3 |
| C9orf116 | OLFM1 | 0.715564 | 3 | 0 | 3 |
| C9orf116 | KIFC1 | 0.705379 | 3 | 0 | 3 |
| C9orf116 | ACY1 | 0.704278 | 3 | 0 | 3 |
| C9orf116 | CNKSR1 | 0.697462 | 3 | 0 | 3 |
| C9orf116 | MIEN1 | 0.697029 | 3 | 0 | 3 |
| C9orf116 | C16orf58 | 0.690281 | 3 | 0 | 3 |
| C9orf116 | SLC9A1 | 0.689708 | 3 | 0 | 3 |
| C9orf116 | BAG6 | 0.689071 | 3 | 0 | 3 |
| C9orf116 | HOXA7 | 0.68253 | 3 | 0 | 3 |
| C9orf116 | PHLDA3 | 0.67758 | 3 | 0 | 3 |
| C9orf116 | GLIS3 | 0.674958 | 3 | 0 | 3 |
| C9orf116 | SLC25A29 | 0.673233 | 3 | 0 | 3 |
| C9orf116 | PACS1 | 0.668899 | 3 | 0 | 3 |
| C9orf116 | KDM5C | 0.667901 | 4 | 0 | 4 |
| C9orf116 | HCFC1 | 0.66656 | 3 | 0 | 3 |
| C9orf116 | KHDC3L | 0.665454 | 3 | 0 | 3 |
| C9orf116 | TBX20 | 0.664644 | 3 | 0 | 3 |
| C9orf116 | UBA1 | 0.662093 | 4 | 0 | 3 |
For details and further investigation, click here
