PTER

 

Full name: phosphotriesterase related Alias Symbol: 
Type: protein-coding gene Cytoband: 10p13
Entrez ID: 9317 HGNC ID: HGNC:9590 Ensembl Gene: ENSG00000165983 OMIM ID: 604446
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of PTER:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PTER 9317 222798_at 0.1442 0.5509
GSE20347 PTER 9317 218967_s_at -0.2814 0.3583
GSE23400 PTER 9317 218967_s_at 0.2933 0.0000
GSE26886 PTER 9317 222798_at 0.3674 0.2900
GSE29001 PTER 9317 218967_s_at 0.2829 0.4873
GSE38129 PTER 9317 218967_s_at -0.2199 0.5177
GSE45670 PTER 9317 222798_at -0.0486 0.9031
GSE53622 PTER 9317 25445 -0.1753 0.1452
GSE53624 PTER 9317 25445 -0.1775 0.0652
GSE63941 PTER 9317 218967_s_at 2.2297 0.1733
GSE77861 PTER 9317 222798_at -0.2148 0.6416
GSE97050 PTER 9317 A_33_P3317253 0.0182 0.9500
SRP007169 PTER 9317 RNAseq 0.1027 0.8937
SRP064894 PTER 9317 RNAseq -0.0700 0.6829
SRP133303 PTER 9317 RNAseq 0.0456 0.8346
SRP159526 PTER 9317 RNAseq -0.6473 0.0340
SRP193095 PTER 9317 RNAseq -0.7784 0.0003
SRP219564 PTER 9317 RNAseq -0.4098 0.3760
TCGA PTER 9317 RNAseq -0.3210 0.0001

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PTER expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PTER:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PTER 9317 3 8 19
GSE20123 PTER 9317 3 7 20
GSE43470 PTER 9317 3 5 35
GSE46452 PTER 9317 1 14 44
GSE47630 PTER 9317 5 15 20
GSE54993 PTER 9317 10 0 60
GSE54994 PTER 9317 4 9 40
GSE60625 PTER 9317 0 0 11
GSE74703 PTER 9317 2 3 31
GSE74704 PTER 9317 0 6 14
TCGA PTER 9317 20 25 51

Total number of gains: 51; Total number of losses: 92; Total Number of normals: 345.  


 

Somatic mutations of PTER:

 

Generating mutation plots.

 

Highly correlated genes for PTER:

 

Showing top 20/187 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PTERCDCA70.803177303
PTERZNF2510.764625303
PTERZNF2340.751699303
PTERZC3H150.732573303
PTERUTP230.732381303
PTERRBM230.731969303
PTERCISD20.73136303
PTERSUZ120.723839303
PTERTMEM2090.715243303
PTERFAM200A0.713597303
PTERBARD10.709968303
PTERSMYD20.708641303
PTERFGFR1OP0.699536303
PTERTBP0.699079303
PTERZNF7650.697504303
PTERCEP1280.695401303
PTERVGLL40.694831303
PTERPHIP0.693484303
PTERZNF8080.692814303
PTERIFNGR10.69124303

For details and further investigation, click here