| Full name: CDGSH iron sulfur domain 2 | Alias Symbol: Miner1|ERIS|NAF-1 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 493856 | HGNC ID: HGNC:24212 | Ensembl Gene: ENSG00000145354 | OMIM ID: 611507 |
| Drug and gene relationship at DGIdb | |||
Expression of CISD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CISD2 | 493856 | 226689_at | 0.4746 | 0.0809 | |
| GSE26886 | CISD2 | 493856 | 226689_at | -0.2410 | 0.3924 | |
| GSE45670 | CISD2 | 493856 | 226689_at | 0.2126 | 0.0789 | |
| GSE53622 | CISD2 | 493856 | 174848 | 0.1649 | 0.1168 | |
| GSE53624 | CISD2 | 493856 | 174848 | 0.3787 | 0.0000 | |
| GSE63941 | CISD2 | 493856 | 226686_at | 0.1441 | 0.7394 | |
| GSE77861 | CISD2 | 493856 | 226689_at | 0.1527 | 0.7083 | |
| GSE97050 | CISD2 | 493856 | A_33_P3362641 | 0.3853 | 0.1613 | |
| SRP007169 | CISD2 | 493856 | RNAseq | 0.0136 | 0.9737 | |
| SRP008496 | CISD2 | 493856 | RNAseq | 0.1558 | 0.5119 | |
| SRP064894 | CISD2 | 493856 | RNAseq | 0.5093 | 0.0046 | |
| SRP133303 | CISD2 | 493856 | RNAseq | 0.8877 | 0.0000 | |
| SRP159526 | CISD2 | 493856 | RNAseq | 0.4595 | 0.0009 | |
| SRP193095 | CISD2 | 493856 | RNAseq | 0.0780 | 0.5851 | |
| SRP219564 | CISD2 | 493856 | RNAseq | 0.3943 | 0.2080 | |
| TCGA | CISD2 | 493856 | RNAseq | 0.1541 | 0.0064 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CISD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CISD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CISD2 | 493856 | 0 | 12 | 18 | |
| GSE20123 | CISD2 | 493856 | 0 | 12 | 18 | |
| GSE43470 | CISD2 | 493856 | 0 | 13 | 30 | |
| GSE46452 | CISD2 | 493856 | 1 | 36 | 22 | |
| GSE47630 | CISD2 | 493856 | 0 | 20 | 20 | |
| GSE54993 | CISD2 | 493856 | 9 | 0 | 61 | |
| GSE54994 | CISD2 | 493856 | 1 | 10 | 42 | |
| GSE60625 | CISD2 | 493856 | 0 | 3 | 8 | |
| GSE74703 | CISD2 | 493856 | 0 | 11 | 25 | |
| GSE74704 | CISD2 | 493856 | 0 | 6 | 14 | |
| TCGA | CISD2 | 493856 | 8 | 39 | 49 |
Total number of gains: 19; Total number of losses: 162; Total Number of normals: 307.
Somatic mutations of CISD2:
Generating mutation plots.
Highly correlated genes for CISD2:
Showing top 20/253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CISD2 | SRRD | 0.841939 | 3 | 0 | 3 |
| CISD2 | PMS1 | 0.815036 | 3 | 0 | 3 |
| CISD2 | CXCL16 | 0.794065 | 3 | 0 | 3 |
| CISD2 | TMEM138 | 0.790853 | 3 | 0 | 3 |
| CISD2 | PSTPIP2 | 0.779305 | 3 | 0 | 3 |
| CISD2 | DPP9 | 0.771415 | 3 | 0 | 3 |
| CISD2 | TMEM123 | 0.76385 | 3 | 0 | 3 |
| CISD2 | MAK16 | 0.760053 | 3 | 0 | 3 |
| CISD2 | STK3 | 0.755026 | 3 | 0 | 3 |
| CISD2 | PAICS | 0.753237 | 4 | 0 | 3 |
| CISD2 | SFR1 | 0.747371 | 3 | 0 | 3 |
| CISD2 | GMEB2 | 0.740382 | 3 | 0 | 3 |
| CISD2 | MTRR | 0.739417 | 3 | 0 | 3 |
| CISD2 | PTPN4 | 0.738444 | 3 | 0 | 3 |
| CISD2 | TMEM237 | 0.732851 | 3 | 0 | 3 |
| CISD2 | SLC39A6 | 0.732388 | 3 | 0 | 3 |
| CISD2 | PTER | 0.73136 | 3 | 0 | 3 |
| CISD2 | UBA2 | 0.730812 | 3 | 0 | 3 |
| CISD2 | ASPH | 0.727821 | 3 | 0 | 3 |
| CISD2 | CEP85 | 0.722864 | 3 | 0 | 3 |
For details and further investigation, click here
