| Full name: pleckstrin homology domain interacting protein | Alias Symbol: ndrp|FLJ20705|DCAF14|BRWD2 | ||
| Type: protein-coding gene | Cytoband: 6q14.1 | ||
| Entrez ID: 55023 | HGNC ID: HGNC:15673 | Ensembl Gene: ENSG00000146247 | OMIM ID: 612870 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PHIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHIP | 55023 | 213074_at | 0.2602 | 0.4646 | |
| GSE20347 | PHIP | 55023 | 213074_at | 0.5741 | 0.0263 | |
| GSE23400 | PHIP | 55023 | 213074_at | 0.2874 | 0.0000 | |
| GSE26886 | PHIP | 55023 | 213074_at | 1.2279 | 0.0000 | |
| GSE29001 | PHIP | 55023 | 213074_at | 0.4592 | 0.1976 | |
| GSE38129 | PHIP | 55023 | 213074_at | 0.3470 | 0.0549 | |
| GSE45670 | PHIP | 55023 | 213074_at | 0.0699 | 0.6771 | |
| GSE53622 | PHIP | 55023 | 56822 | 0.3494 | 0.0000 | |
| GSE53624 | PHIP | 55023 | 56822 | 0.2424 | 0.0000 | |
| GSE63941 | PHIP | 55023 | 212542_s_at | 0.0487 | 0.9315 | |
| GSE77861 | PHIP | 55023 | 213074_at | 0.5783 | 0.0366 | |
| GSE97050 | PHIP | 55023 | A_33_P3312246 | -0.1687 | 0.5187 | |
| SRP007169 | PHIP | 55023 | RNAseq | 0.8724 | 0.0288 | |
| SRP008496 | PHIP | 55023 | RNAseq | 0.6515 | 0.0036 | |
| SRP064894 | PHIP | 55023 | RNAseq | 0.1834 | 0.3302 | |
| SRP133303 | PHIP | 55023 | RNAseq | 0.2487 | 0.0649 | |
| SRP159526 | PHIP | 55023 | RNAseq | 0.2209 | 0.3095 | |
| SRP193095 | PHIP | 55023 | RNAseq | 0.1156 | 0.1517 | |
| SRP219564 | PHIP | 55023 | RNAseq | -0.2333 | 0.4655 | |
| TCGA | PHIP | 55023 | RNAseq | -0.0037 | 0.9334 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PHIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHIP | 55023 | 2 | 4 | 24 | |
| GSE20123 | PHIP | 55023 | 2 | 3 | 25 | |
| GSE43470 | PHIP | 55023 | 2 | 1 | 40 | |
| GSE46452 | PHIP | 55023 | 3 | 11 | 45 | |
| GSE47630 | PHIP | 55023 | 8 | 6 | 26 | |
| GSE54993 | PHIP | 55023 | 3 | 2 | 65 | |
| GSE54994 | PHIP | 55023 | 8 | 7 | 38 | |
| GSE60625 | PHIP | 55023 | 0 | 1 | 10 | |
| GSE74703 | PHIP | 55023 | 2 | 1 | 33 | |
| GSE74704 | PHIP | 55023 | 1 | 2 | 17 | |
| TCGA | PHIP | 55023 | 6 | 22 | 68 |
Total number of gains: 37; Total number of losses: 60; Total Number of normals: 391.
Somatic mutations of PHIP:
Generating mutation plots.
Highly correlated genes for PHIP:
Showing top 20/1080 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHIP | WDR81 | 0.823847 | 3 | 0 | 3 |
| PHIP | DHRSX | 0.81377 | 3 | 0 | 3 |
| PHIP | KLHL13 | 0.806523 | 3 | 0 | 3 |
| PHIP | ARHGAP24 | 0.804102 | 3 | 0 | 3 |
| PHIP | PLEKHA3 | 0.802706 | 4 | 0 | 4 |
| PHIP | ZCCHC3 | 0.802437 | 3 | 0 | 3 |
| PHIP | B3GALNT2 | 0.796858 | 3 | 0 | 3 |
| PHIP | SP100 | 0.794521 | 3 | 0 | 3 |
| PHIP | SORL1 | 0.776028 | 3 | 0 | 3 |
| PHIP | PTPN2 | 0.774767 | 5 | 0 | 5 |
| PHIP | CRTC3 | 0.770853 | 3 | 0 | 3 |
| PHIP | MEF2A | 0.770517 | 3 | 0 | 3 |
| PHIP | KRTCAP2 | 0.769037 | 3 | 0 | 3 |
| PHIP | MRPL9 | 0.765318 | 3 | 0 | 3 |
| PHIP | PHF20 | 0.75981 | 3 | 0 | 3 |
| PHIP | UBR1 | 0.752582 | 3 | 0 | 3 |
| PHIP | GLI3 | 0.749726 | 3 | 0 | 3 |
| PHIP | ZSCAN29 | 0.749414 | 4 | 0 | 4 |
| PHIP | FEZ1 | 0.749053 | 3 | 0 | 3 |
| PHIP | TIMM9 | 0.74831 | 4 | 0 | 4 |
For details and further investigation, click here
