| Full name: FGFR1 oncogene partner | Alias Symbol: FOP | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 11116 | HGNC ID: HGNC:17012 | Ensembl Gene: ENSG00000213066 | OMIM ID: 605392 |
| Drug and gene relationship at DGIdb | |||
Expression of FGFR1OP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGFR1OP | 11116 | 214124_x_at | 0.1786 | 0.7424 | |
| GSE20347 | FGFR1OP | 11116 | 214124_x_at | 0.0429 | 0.7863 | |
| GSE23400 | FGFR1OP | 11116 | 205588_s_at | 0.3646 | 0.0000 | |
| GSE26886 | FGFR1OP | 11116 | 214124_x_at | 0.3550 | 0.1137 | |
| GSE29001 | FGFR1OP | 11116 | 205588_s_at | 0.2453 | 0.5138 | |
| GSE38129 | FGFR1OP | 11116 | 214124_x_at | 0.1011 | 0.4948 | |
| GSE45670 | FGFR1OP | 11116 | 1568678_s_at | 0.9163 | 0.0000 | |
| GSE53622 | FGFR1OP | 11116 | 49812 | 0.3087 | 0.0001 | |
| GSE53624 | FGFR1OP | 11116 | 49812 | 0.5952 | 0.0000 | |
| GSE63941 | FGFR1OP | 11116 | 214124_x_at | 0.1996 | 0.6939 | |
| GSE77861 | FGFR1OP | 11116 | 214124_x_at | 0.0204 | 0.9327 | |
| GSE97050 | FGFR1OP | 11116 | A_23_P145134 | 0.6515 | 0.2109 | |
| SRP007169 | FGFR1OP | 11116 | RNAseq | 1.4945 | 0.0095 | |
| SRP008496 | FGFR1OP | 11116 | RNAseq | 1.2076 | 0.0033 | |
| SRP064894 | FGFR1OP | 11116 | RNAseq | 0.3235 | 0.1133 | |
| SRP133303 | FGFR1OP | 11116 | RNAseq | 0.2512 | 0.0332 | |
| SRP159526 | FGFR1OP | 11116 | RNAseq | 0.2918 | 0.4408 | |
| SRP193095 | FGFR1OP | 11116 | RNAseq | -0.0495 | 0.5938 | |
| SRP219564 | FGFR1OP | 11116 | RNAseq | -0.0661 | 0.7503 | |
| TCGA | FGFR1OP | 11116 | RNAseq | 0.1366 | 0.0630 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FGFR1OP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGFR1OP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGFR1OP | 11116 | 2 | 6 | 22 | |
| GSE20123 | FGFR1OP | 11116 | 2 | 6 | 22 | |
| GSE43470 | FGFR1OP | 11116 | 3 | 0 | 40 | |
| GSE46452 | FGFR1OP | 11116 | 3 | 10 | 46 | |
| GSE47630 | FGFR1OP | 11116 | 7 | 7 | 26 | |
| GSE54993 | FGFR1OP | 11116 | 4 | 3 | 63 | |
| GSE54994 | FGFR1OP | 11116 | 10 | 8 | 35 | |
| GSE60625 | FGFR1OP | 11116 | 1 | 1 | 9 | |
| GSE74703 | FGFR1OP | 11116 | 3 | 0 | 33 | |
| GSE74704 | FGFR1OP | 11116 | 1 | 3 | 16 | |
| TCGA | FGFR1OP | 11116 | 13 | 23 | 60 |
Total number of gains: 49; Total number of losses: 67; Total Number of normals: 372.
Somatic mutations of FGFR1OP:
Generating mutation plots.
Highly correlated genes for FGFR1OP:
Showing top 20/612 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGFR1OP | RRM2B | 0.771975 | 3 | 0 | 3 |
| FGFR1OP | PRDM15 | 0.735597 | 3 | 0 | 3 |
| FGFR1OP | TMEM131 | 0.726634 | 3 | 0 | 3 |
| FGFR1OP | APOBEC3G | 0.724321 | 3 | 0 | 3 |
| FGFR1OP | ZNF681 | 0.708049 | 3 | 0 | 3 |
| FGFR1OP | ERCC6 | 0.705312 | 4 | 0 | 3 |
| FGFR1OP | ERP27 | 0.702153 | 4 | 0 | 4 |
| FGFR1OP | FARSA | 0.701395 | 4 | 0 | 4 |
| FGFR1OP | MRI1 | 0.700645 | 3 | 0 | 3 |
| FGFR1OP | PTER | 0.699536 | 3 | 0 | 3 |
| FGFR1OP | SRGAP1 | 0.699478 | 3 | 0 | 3 |
| FGFR1OP | RNF13 | 0.694475 | 3 | 0 | 3 |
| FGFR1OP | FBXW9 | 0.680573 | 3 | 0 | 3 |
| FGFR1OP | ZNF165 | 0.680459 | 4 | 0 | 4 |
| FGFR1OP | ENTPD4 | 0.675121 | 3 | 0 | 3 |
| FGFR1OP | PKMYT1 | 0.668217 | 3 | 0 | 3 |
| FGFR1OP | MIS18A | 0.667683 | 6 | 0 | 5 |
| FGFR1OP | SUN1 | 0.666222 | 3 | 0 | 3 |
| FGFR1OP | ZNF266 | 0.663432 | 3 | 0 | 3 |
| FGFR1OP | DPP3 | 0.657856 | 5 | 0 | 4 |
For details and further investigation, click here
