| Full name: SET and MYND domain containing 2 | Alias Symbol: HSKM-B|ZMYND14|KMT3C | ||
| Type: protein-coding gene | Cytoband: 1q32.3 | ||
| Entrez ID: 56950 | HGNC ID: HGNC:20982 | Ensembl Gene: ENSG00000143499 | OMIM ID: 610663 |
| Drug and gene relationship at DGIdb | |||
Expression of SMYD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMYD2 | 56950 | 212922_s_at | 0.5232 | 0.1401 | |
| GSE20347 | SMYD2 | 56950 | 212922_s_at | 0.1589 | 0.3393 | |
| GSE23400 | SMYD2 | 56950 | 212922_s_at | 0.5707 | 0.0000 | |
| GSE26886 | SMYD2 | 56950 | 212922_s_at | 0.7873 | 0.0011 | |
| GSE29001 | SMYD2 | 56950 | 212922_s_at | 0.1901 | 0.7393 | |
| GSE38129 | SMYD2 | 56950 | 212922_s_at | 0.5347 | 0.0001 | |
| GSE45670 | SMYD2 | 56950 | 212922_s_at | 0.3039 | 0.0251 | |
| GSE53622 | SMYD2 | 56950 | 79311 | 0.3795 | 0.0000 | |
| GSE53624 | SMYD2 | 56950 | 79311 | 0.3989 | 0.0000 | |
| GSE63941 | SMYD2 | 56950 | 212922_s_at | 0.1584 | 0.7706 | |
| GSE77861 | SMYD2 | 56950 | 212922_s_at | 0.4620 | 0.1261 | |
| GSE97050 | SMYD2 | 56950 | A_23_P170587 | 0.3244 | 0.2579 | |
| SRP007169 | SMYD2 | 56950 | RNAseq | 0.2381 | 0.5516 | |
| SRP008496 | SMYD2 | 56950 | RNAseq | 0.2166 | 0.4418 | |
| SRP064894 | SMYD2 | 56950 | RNAseq | 0.6593 | 0.0054 | |
| SRP133303 | SMYD2 | 56950 | RNAseq | 0.4400 | 0.0054 | |
| SRP159526 | SMYD2 | 56950 | RNAseq | -0.1891 | 0.5215 | |
| SRP193095 | SMYD2 | 56950 | RNAseq | -0.1207 | 0.3842 | |
| SRP219564 | SMYD2 | 56950 | RNAseq | 0.2710 | 0.4055 | |
| TCGA | SMYD2 | 56950 | RNAseq | 0.0721 | 0.1900 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMYD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMYD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMYD2 | 56950 | 9 | 0 | 21 | |
| GSE20123 | SMYD2 | 56950 | 9 | 0 | 21 | |
| GSE43470 | SMYD2 | 56950 | 7 | 1 | 35 | |
| GSE46452 | SMYD2 | 56950 | 3 | 1 | 55 | |
| GSE47630 | SMYD2 | 56950 | 15 | 0 | 25 | |
| GSE54993 | SMYD2 | 56950 | 0 | 6 | 64 | |
| GSE54994 | SMYD2 | 56950 | 14 | 0 | 39 | |
| GSE60625 | SMYD2 | 56950 | 0 | 0 | 11 | |
| GSE74703 | SMYD2 | 56950 | 7 | 1 | 28 | |
| GSE74704 | SMYD2 | 56950 | 3 | 0 | 17 | |
| TCGA | SMYD2 | 56950 | 44 | 3 | 49 |
Total number of gains: 111; Total number of losses: 12; Total Number of normals: 365.
Somatic mutations of SMYD2:
Generating mutation plots.
Highly correlated genes for SMYD2:
Showing top 20/1209 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMYD2 | ROMO1 | 0.831012 | 3 | 0 | 3 |
| SMYD2 | TMEM63B | 0.790929 | 3 | 0 | 3 |
| SMYD2 | CPT1A | 0.787384 | 3 | 0 | 3 |
| SMYD2 | LIMS1 | 0.764594 | 3 | 0 | 3 |
| SMYD2 | RNF4 | 0.764346 | 3 | 0 | 3 |
| SMYD2 | KRTCAP2 | 0.761713 | 5 | 0 | 5 |
| SMYD2 | GPR153 | 0.747701 | 5 | 0 | 5 |
| SMYD2 | CAMKK1 | 0.743422 | 3 | 0 | 3 |
| SMYD2 | RLIM | 0.738607 | 3 | 0 | 3 |
| SMYD2 | DYNC2H1 | 0.737509 | 4 | 0 | 4 |
| SMYD2 | CHST3 | 0.7363 | 3 | 0 | 3 |
| SMYD2 | CEP250 | 0.731099 | 3 | 0 | 3 |
| SMYD2 | TOMM40L | 0.720873 | 3 | 0 | 3 |
| SMYD2 | CCDC127 | 0.720619 | 3 | 0 | 3 |
| SMYD2 | C9orf64 | 0.716697 | 3 | 0 | 3 |
| SMYD2 | ZSCAN21 | 0.714015 | 3 | 0 | 3 |
| SMYD2 | MRPS5 | 0.711057 | 3 | 0 | 3 |
| SMYD2 | UBA52 | 0.709795 | 3 | 0 | 3 |
| SMYD2 | RAD18 | 0.70925 | 3 | 0 | 3 |
| SMYD2 | COMMD5 | 0.708954 | 4 | 0 | 3 |
For details and further investigation, click here
