| Full name: zinc finger protein 251 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 90987 | HGNC ID: HGNC:13045 | Ensembl Gene: ENSG00000198169 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF251:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF251 | 90987 | 226754_at | 0.2962 | 0.7308 | |
| GSE26886 | ZNF251 | 90987 | 226754_at | 0.7784 | 0.0004 | |
| GSE45670 | ZNF251 | 90987 | 226754_at | -0.1261 | 0.4594 | |
| GSE53622 | ZNF251 | 90987 | 33280 | 0.2044 | 0.0832 | |
| GSE53624 | ZNF251 | 90987 | 33280 | 0.1400 | 0.1482 | |
| GSE63941 | ZNF251 | 90987 | 226754_at | -0.5848 | 0.3583 | |
| GSE77861 | ZNF251 | 90987 | 226754_at | 0.1044 | 0.4197 | |
| GSE97050 | ZNF251 | 90987 | A_24_P49517 | -0.0633 | 0.8599 | |
| SRP007169 | ZNF251 | 90987 | RNAseq | 0.5201 | 0.4390 | |
| SRP008496 | ZNF251 | 90987 | RNAseq | 1.2096 | 0.0221 | |
| SRP064894 | ZNF251 | 90987 | RNAseq | 0.4715 | 0.0507 | |
| SRP133303 | ZNF251 | 90987 | RNAseq | 0.0741 | 0.7303 | |
| SRP159526 | ZNF251 | 90987 | RNAseq | -0.0644 | 0.8724 | |
| SRP193095 | ZNF251 | 90987 | RNAseq | 0.3752 | 0.0044 | |
| SRP219564 | ZNF251 | 90987 | RNAseq | 0.4820 | 0.3050 | |
| TCGA | ZNF251 | 90987 | RNAseq | 0.0361 | 0.6724 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF251 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF251:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF251 | 90987 | 18 | 1 | 11 | |
| GSE20123 | ZNF251 | 90987 | 18 | 1 | 11 | |
| GSE43470 | ZNF251 | 90987 | 16 | 2 | 25 | |
| GSE46452 | ZNF251 | 90987 | 28 | 0 | 31 | |
| GSE47630 | ZNF251 | 90987 | 25 | 1 | 14 | |
| GSE54993 | ZNF251 | 90987 | 0 | 25 | 45 | |
| GSE54994 | ZNF251 | 90987 | 39 | 1 | 13 | |
| GSE60625 | ZNF251 | 90987 | 3 | 4 | 4 | |
| GSE74703 | ZNF251 | 90987 | 14 | 1 | 21 | |
| GSE74704 | ZNF251 | 90987 | 11 | 0 | 9 | |
| TCGA | ZNF251 | 90987 | 63 | 2 | 31 |
Total number of gains: 235; Total number of losses: 38; Total Number of normals: 215.
Somatic mutations of ZNF251:
Generating mutation plots.
Highly correlated genes for ZNF251:
Showing top 20/442 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF251 | METTL3 | 0.858632 | 3 | 0 | 3 |
| ZNF251 | USP28 | 0.811527 | 3 | 0 | 3 |
| ZNF251 | PTPN4 | 0.811453 | 3 | 0 | 3 |
| ZNF251 | RNF130 | 0.810509 | 3 | 0 | 3 |
| ZNF251 | KRTCAP2 | 0.789702 | 4 | 0 | 4 |
| ZNF251 | FIP1L1 | 0.789648 | 3 | 0 | 3 |
| ZNF251 | SPEN | 0.7834 | 3 | 0 | 3 |
| ZNF251 | MAD2L2 | 0.780002 | 3 | 0 | 3 |
| ZNF251 | BOLA1 | 0.776812 | 3 | 0 | 3 |
| ZNF251 | CERS2 | 0.769461 | 3 | 0 | 3 |
| ZNF251 | ZNF284 | 0.767877 | 3 | 0 | 3 |
| ZNF251 | ZSCAN21 | 0.765832 | 3 | 0 | 3 |
| ZNF251 | PTER | 0.764625 | 3 | 0 | 3 |
| ZNF251 | MRFAP1L1 | 0.749956 | 3 | 0 | 3 |
| ZNF251 | RIMKLB | 0.749851 | 3 | 0 | 3 |
| ZNF251 | NOL10 | 0.747085 | 3 | 0 | 3 |
| ZNF251 | INTS3 | 0.746879 | 3 | 0 | 3 |
| ZNF251 | SNRNP70 | 0.74375 | 3 | 0 | 3 |
| ZNF251 | MSH6 | 0.742955 | 3 | 0 | 3 |
| ZNF251 | TCEA1 | 0.742811 | 4 | 0 | 4 |
For details and further investigation, click here
