RPS5

 

Full name: ribosomal protein S5 Alias Symbol: S5
Type: protein-coding gene Cytoband: 19q13.4
Entrez ID: 6193 HGNC ID: HGNC:10426 Ensembl Gene: ENSG00000083845 OMIM ID: 603630
Drug and gene relationship at DGIdb

 

Expression of RPS5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RPS5 6193 200024_at -0.0437 0.9011
GSE20347 RPS5 6193 200024_at -0.2774 0.0473
GSE23400 RPS5 6193 200024_at -0.1800 0.0056
GSE26886 RPS5 6193 200024_at 0.2033 0.4152
GSE29001 RPS5 6193 200024_at -0.5576 0.1956
GSE38129 RPS5 6193 200024_at -0.1558 0.2083
GSE45670 RPS5 6193 200024_at -0.3877 0.0002
GSE53622 RPS5 6193 106244 -0.4627 0.0000
GSE53624 RPS5 6193 77961 0.1138 0.1295
GSE63941 RPS5 6193 200024_at 0.8985 0.0003
GSE77861 RPS5 6193 200024_at -0.3385 0.1737
GSE97050 RPS5 6193 A_33_P3300817 -0.3246 0.3332
SRP007169 RPS5 6193 RNAseq -1.3338 0.0005
SRP008496 RPS5 6193 RNAseq -1.3430 0.0000
SRP064894 RPS5 6193 RNAseq -0.2312 0.5374
SRP133303 RPS5 6193 RNAseq -0.5160 0.0377
SRP159526 RPS5 6193 RNAseq -0.4541 0.0729
SRP193095 RPS5 6193 RNAseq -0.8198 0.0000
SRP219564 RPS5 6193 RNAseq -0.5281 0.0077
TCGA RPS5 6193 RNAseq 0.0288 0.5919

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by RPS5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPS5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPS5 6193 2 5 23
GSE20123 RPS5 6193 2 4 24
GSE43470 RPS5 6193 3 9 31
GSE46452 RPS5 6193 45 1 13
GSE47630 RPS5 6193 7 6 27
GSE54993 RPS5 6193 18 4 48
GSE54994 RPS5 6193 5 12 36
GSE60625 RPS5 6193 9 0 2
GSE74703 RPS5 6193 3 6 27
GSE74704 RPS5 6193 2 1 17
TCGA RPS5 6193 20 19 57

Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.  

 

Somatic mutations of RPS5:

 

Generating mutation plots.

 

Highly correlated genes for RPS5:

 

Showing top 20/485 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPS5RPL180.79639312011
RPS5NUDT160.765884303
RPS5RPL13A0.750025404
RPS5RPS140.7296671109
RPS5STARD100.725285303
RPS5PEX20.723137303
RPS5GPR1600.714766303
RPS5RPL18A0.71107303
RPS5RPS90.70729413011
RPS5KRT180.696808303
RPS5GIMAP80.695273303
RPS5RNF144B0.687807303
RPS5RPS130.685156404
RPS5CTDSP20.6814303
RPS5RPL410.681019806
RPS5ZNF410.675171303
RPS5RPL110.6726251109
RPS5N4BP2L10.669298303
RPS5RPL30.6659221007
RPS5ABHD14B0.665575404

For details and further investigation, click here