ABHD14B

 

Full name: abhydrolase domain containing 14B Alias Symbol: MGC15429|CIB
Type: protein-coding gene Cytoband: 3p21.2
Entrez ID: 84836 HGNC ID: HGNC:28235 Ensembl Gene: ENSG00000114779 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ABHD14B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABHD14B 84836 224821_at -0.5783 0.4479
GSE26886 ABHD14B 84836 224821_at -0.6697 0.0003
GSE45670 ABHD14B 84836 224821_at -0.5719 0.0008
GSE53622 ABHD14B 84836 16789 -1.0896 0.0000
GSE53624 ABHD14B 84836 16235 -0.6459 0.0000
GSE63941 ABHD14B 84836 224821_at -0.1111 0.8812
GSE77861 ABHD14B 84836 224821_at -0.6759 0.1023
GSE97050 ABHD14B 84836 A_23_P155417 -0.4366 0.1133
SRP007169 ABHD14B 84836 RNAseq -1.9014 0.0000
SRP008496 ABHD14B 84836 RNAseq -1.8071 0.0000
SRP064894 ABHD14B 84836 RNAseq -0.6705 0.0025
SRP133303 ABHD14B 84836 RNAseq -1.0454 0.0000
SRP159526 ABHD14B 84836 RNAseq -0.8693 0.0099
SRP193095 ABHD14B 84836 RNAseq -1.1446 0.0000
SRP219564 ABHD14B 84836 RNAseq -0.5108 0.2665
TCGA ABHD14B 84836 RNAseq -0.3000 0.0000

Upregulated datasets: 0; Downregulated datasets: 5.  


 

Survival by ABHD14B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABHD14B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABHD14B 84836 0 18 12
GSE20123 ABHD14B 84836 0 19 11
GSE43470 ABHD14B 84836 0 18 25
GSE46452 ABHD14B 84836 2 17 40
GSE47630 ABHD14B 84836 1 24 15
GSE54993 ABHD14B 84836 6 2 62
GSE54994 ABHD14B 84836 0 34 19
GSE60625 ABHD14B 84836 5 0 6
GSE74703 ABHD14B 84836 0 14 22
GSE74704 ABHD14B 84836 0 12 8
TCGA ABHD14B 84836 0 78 18

Total number of gains: 14; Total number of losses: 236; Total Number of normals: 238.  


 

Somatic mutations of ABHD14B:

 

Generating mutation plots.

 

Highly correlated genes for ABHD14B:

 

Showing top 20/1330 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABHD14BPPP1R110.82051303
ABHD14BPARP160.80312303
ABHD14BMORC30.788347303
ABHD14BFRAS10.775957303
ABHD14BTLE20.768909404
ABHD14BAP3M10.768622404
ABHD14BWBP20.763156505
ABHD14BMXD30.760259303
ABHD14BTTLL10.757316303
ABHD14BKBTBD40.755577303
ABHD14BCLTA0.751415404
ABHD14BRPS90.747831404
ABHD14BP4HTM0.74425404
ABHD14BGOLGA40.743686303
ABHD14BKCNJ50.743575303
ABHD14BCD990.740089303
ABHD14BHINT30.738375303
ABHD14BLRRC280.737595303
ABHD14BRPL140.736166303
ABHD14BCIDEB0.732081303

For details and further investigation, click here