| Full name: peroxisomal biogenesis factor 2 | Alias Symbol: PMP35|PAF-1|RNF72|ZWS3 | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 5828 | HGNC ID: HGNC:9717 | Ensembl Gene: ENSG00000164751 | OMIM ID: 170993 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX2 | 5828 | 210296_s_at | 0.2253 | 0.6058 | |
| GSE20347 | PEX2 | 5828 | 210296_s_at | 0.2844 | 0.1649 | |
| GSE23400 | PEX2 | 5828 | 210296_s_at | 0.3528 | 0.0000 | |
| GSE26886 | PEX2 | 5828 | 210296_s_at | -1.1778 | 0.0005 | |
| GSE29001 | PEX2 | 5828 | 210296_s_at | 0.1401 | 0.7678 | |
| GSE38129 | PEX2 | 5828 | 210296_s_at | 0.2848 | 0.0780 | |
| GSE45670 | PEX2 | 5828 | 210296_s_at | 0.1074 | 0.4317 | |
| GSE53622 | PEX2 | 5828 | 75727 | -0.1765 | 0.1777 | |
| GSE53624 | PEX2 | 5828 | 75727 | -0.1103 | 0.4086 | |
| GSE63941 | PEX2 | 5828 | 210296_s_at | 0.0378 | 0.9533 | |
| GSE77861 | PEX2 | 5828 | 210296_s_at | -0.1360 | 0.7721 | |
| GSE97050 | PEX2 | 5828 | A_33_P3351027 | 0.0205 | 0.9385 | |
| SRP007169 | PEX2 | 5828 | RNAseq | -0.5194 | 0.1122 | |
| SRP008496 | PEX2 | 5828 | RNAseq | -0.2868 | 0.1998 | |
| SRP064894 | PEX2 | 5828 | RNAseq | 0.1246 | 0.4890 | |
| SRP133303 | PEX2 | 5828 | RNAseq | -0.0468 | 0.6652 | |
| SRP159526 | PEX2 | 5828 | RNAseq | -0.2411 | 0.3054 | |
| SRP193095 | PEX2 | 5828 | RNAseq | -0.4256 | 0.0006 | |
| SRP219564 | PEX2 | 5828 | RNAseq | -0.3485 | 0.1349 | |
| TCGA | PEX2 | 5828 | RNAseq | -0.0917 | 0.0667 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PEX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX2 | 5828 | 15 | 1 | 14 | |
| GSE20123 | PEX2 | 5828 | 17 | 1 | 12 | |
| GSE43470 | PEX2 | 5828 | 18 | 1 | 24 | |
| GSE46452 | PEX2 | 5828 | 21 | 0 | 38 | |
| GSE47630 | PEX2 | 5828 | 23 | 0 | 17 | |
| GSE54993 | PEX2 | 5828 | 0 | 19 | 51 | |
| GSE54994 | PEX2 | 5828 | 30 | 0 | 23 | |
| GSE60625 | PEX2 | 5828 | 0 | 4 | 7 | |
| GSE74703 | PEX2 | 5828 | 15 | 1 | 20 | |
| GSE74704 | PEX2 | 5828 | 11 | 0 | 9 | |
| TCGA | PEX2 | 5828 | 52 | 2 | 42 |
Total number of gains: 202; Total number of losses: 29; Total Number of normals: 257.
Somatic mutations of PEX2:
Generating mutation plots.
Highly correlated genes for PEX2:
Showing top 20/628 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX2 | IREB2 | 0.829942 | 3 | 0 | 3 |
| PEX2 | STX18 | 0.805153 | 3 | 0 | 3 |
| PEX2 | USP38 | 0.791063 | 3 | 0 | 3 |
| PEX2 | RIOK2 | 0.77726 | 3 | 0 | 3 |
| PEX2 | CEBPG | 0.773479 | 3 | 0 | 3 |
| PEX2 | SLC44A3 | 0.77227 | 3 | 0 | 3 |
| PEX2 | RBM8A | 0.764274 | 3 | 0 | 3 |
| PEX2 | NDUFAF1 | 0.759028 | 3 | 0 | 3 |
| PEX2 | FBXO3 | 0.755305 | 3 | 0 | 3 |
| PEX2 | CHMP2A | 0.754312 | 3 | 0 | 3 |
| PEX2 | APPL2 | 0.746559 | 3 | 0 | 3 |
| PEX2 | PRKX | 0.741868 | 3 | 0 | 3 |
| PEX2 | ARHGAP18 | 0.739954 | 3 | 0 | 3 |
| PEX2 | PLS1 | 0.737108 | 3 | 0 | 3 |
| PEX2 | NFKB1 | 0.736017 | 6 | 0 | 6 |
| PEX2 | GK5 | 0.73073 | 3 | 0 | 3 |
| PEX2 | ERP29 | 0.728914 | 3 | 0 | 3 |
| PEX2 | TRAPPC2L | 0.72772 | 4 | 0 | 4 |
| PEX2 | KLF3 | 0.725785 | 3 | 0 | 3 |
| PEX2 | RPS5 | 0.723137 | 3 | 0 | 3 |
For details and further investigation, click here
