| Full name: ribosomal protein L41 | Alias Symbol: L41 | ||
| Type: protein-coding gene | Cytoband: 12q13 | ||
| Entrez ID: 6171 | HGNC ID: HGNC:10354 | Ensembl Gene: ENSG00000229117 | OMIM ID: 613315 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL41:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL41 | 6171 | 201492_s_at | -0.1504 | 0.4729 | |
| GSE20347 | RPL41 | 6171 | 201492_s_at | -0.0381 | 0.6469 | |
| GSE23400 | RPL41 | 6171 | 201492_s_at | -0.0359 | 0.2237 | |
| GSE26886 | RPL41 | 6171 | 201492_s_at | 0.0251 | 0.8057 | |
| GSE29001 | RPL41 | 6171 | 201492_s_at | -0.1018 | 0.6410 | |
| GSE38129 | RPL41 | 6171 | 201492_s_at | 0.0098 | 0.8767 | |
| GSE45670 | RPL41 | 6171 | 201492_s_at | -0.0717 | 0.1108 | |
| GSE63941 | RPL41 | 6171 | 201492_s_at | 0.0373 | 0.7583 | |
| GSE77861 | RPL41 | 6171 | 201492_s_at | -0.0334 | 0.7474 | |
| GSE97050 | RPL41 | 6171 | A_23_P128067 | 0.0141 | 0.9712 | |
| SRP007169 | RPL41 | 6171 | RNAseq | -1.3654 | 0.0002 | |
| SRP008496 | RPL41 | 6171 | RNAseq | -1.1923 | 0.0000 | |
| SRP064894 | RPL41 | 6171 | RNAseq | -0.4615 | 0.1632 | |
| SRP133303 | RPL41 | 6171 | RNAseq | -0.4145 | 0.0093 | |
| SRP159526 | RPL41 | 6171 | RNAseq | -0.8644 | 0.0001 | |
| SRP193095 | RPL41 | 6171 | RNAseq | -1.0981 | 0.0000 | |
| SRP219564 | RPL41 | 6171 | RNAseq | -0.5361 | 0.0633 | |
| TCGA | RPL41 | 6171 | RNAseq | -0.0128 | 0.7634 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPL41 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RPL41:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL41 | 6171 | 7 | 2 | 21 | |
| GSE20123 | RPL41 | 6171 | 7 | 1 | 22 | |
| GSE43470 | RPL41 | 6171 | 4 | 0 | 39 | |
| GSE46452 | RPL41 | 6171 | 8 | 1 | 50 | |
| GSE47630 | RPL41 | 6171 | 10 | 2 | 28 | |
| GSE54993 | RPL41 | 6171 | 0 | 5 | 65 | |
| GSE54994 | RPL41 | 6171 | 4 | 1 | 48 | |
| GSE60625 | RPL41 | 6171 | 0 | 0 | 11 | |
| GSE74703 | RPL41 | 6171 | 4 | 0 | 32 | |
| GSE74704 | RPL41 | 6171 | 4 | 1 | 15 | |
| TCGA | RPL41 | 6171 | 15 | 10 | 71 |
Total number of gains: 63; Total number of losses: 23; Total Number of normals: 402.
Somatic mutations of RPL41:
Generating mutation plots.
Highly correlated genes for RPL41:
Showing top 20/447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL41 | XPNPEP1 | 0.798954 | 3 | 0 | 3 |
| RPL41 | NDN | 0.797556 | 3 | 0 | 3 |
| RPL41 | CDC26 | 0.7951 | 3 | 0 | 3 |
| RPL41 | TMEM50A | 0.78394 | 3 | 0 | 3 |
| RPL41 | ZBED5 | 0.749936 | 3 | 0 | 3 |
| RPL41 | NUDT16 | 0.746577 | 4 | 0 | 3 |
| RPL41 | CHMP4B | 0.743278 | 3 | 0 | 3 |
| RPL41 | RARS2 | 0.732395 | 3 | 0 | 3 |
| RPL41 | RERG | 0.728832 | 3 | 0 | 3 |
| RPL41 | LETMD1 | 0.719334 | 5 | 0 | 5 |
| RPL41 | TRIM22 | 0.716515 | 3 | 0 | 3 |
| RPL41 | ELP3 | 0.71475 | 3 | 0 | 3 |
| RPL41 | CYP4V2 | 0.714474 | 3 | 0 | 3 |
| RPL41 | PDSS2 | 0.710925 | 3 | 0 | 3 |
| RPL41 | ATG3 | 0.710061 | 4 | 0 | 4 |
| RPL41 | AP3M1 | 0.709149 | 4 | 0 | 4 |
| RPL41 | SLC17A5 | 0.707971 | 3 | 0 | 3 |
| RPL41 | VPS25 | 0.706269 | 3 | 0 | 3 |
| RPL41 | PDAP1 | 0.701224 | 4 | 0 | 4 |
| RPL41 | SUPT4H1 | 0.699589 | 5 | 0 | 4 |
For details and further investigation, click here
