| Full name: GTPase, IMAP family member 8 | Alias Symbol: DKFZp667I133|hIAN6|IAN9 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 155038 | HGNC ID: HGNC:21792 | Ensembl Gene: ENSG00000171115 | OMIM ID: 616962 |
| Drug and gene relationship at DGIdb | |||
Expression of GIMAP8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIMAP8 | 155038 | 235306_at | -0.5364 | 0.4385 | |
| GSE26886 | GIMAP8 | 155038 | 235306_at | -1.0142 | 0.0101 | |
| GSE45670 | GIMAP8 | 155038 | 235306_at | -1.1882 | 0.0031 | |
| GSE53622 | GIMAP8 | 155038 | 1672 | -0.7577 | 0.0000 | |
| GSE53624 | GIMAP8 | 155038 | 1672 | -0.6345 | 0.0006 | |
| GSE63941 | GIMAP8 | 155038 | 240646_at | 0.1133 | 0.4202 | |
| GSE77861 | GIMAP8 | 155038 | 235306_at | 0.0848 | 0.5750 | |
| GSE97050 | GIMAP8 | 155038 | A_24_P132383 | 0.1221 | 0.6358 | |
| SRP007169 | GIMAP8 | 155038 | RNAseq | 1.3744 | 0.0434 | |
| SRP064894 | GIMAP8 | 155038 | RNAseq | 0.0277 | 0.9400 | |
| SRP133303 | GIMAP8 | 155038 | RNAseq | -0.5961 | 0.0830 | |
| SRP159526 | GIMAP8 | 155038 | RNAseq | -0.4627 | 0.4008 | |
| SRP193095 | GIMAP8 | 155038 | RNAseq | 0.2076 | 0.3639 | |
| SRP219564 | GIMAP8 | 155038 | RNAseq | -0.2528 | 0.5933 | |
| TCGA | GIMAP8 | 155038 | RNAseq | -0.5066 | 0.0006 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by GIMAP8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIMAP8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIMAP8 | 155038 | 2 | 4 | 24 | |
| GSE20123 | GIMAP8 | 155038 | 2 | 4 | 24 | |
| GSE43470 | GIMAP8 | 155038 | 2 | 5 | 36 | |
| GSE46452 | GIMAP8 | 155038 | 7 | 2 | 50 | |
| GSE47630 | GIMAP8 | 155038 | 6 | 8 | 26 | |
| GSE54993 | GIMAP8 | 155038 | 3 | 3 | 64 | |
| GSE54994 | GIMAP8 | 155038 | 6 | 8 | 39 | |
| GSE60625 | GIMAP8 | 155038 | 0 | 0 | 11 | |
| GSE74703 | GIMAP8 | 155038 | 2 | 4 | 30 | |
| GSE74704 | GIMAP8 | 155038 | 1 | 4 | 15 | |
| TCGA | GIMAP8 | 155038 | 25 | 27 | 44 |
Total number of gains: 56; Total number of losses: 69; Total Number of normals: 363.
Somatic mutations of GIMAP8:
Generating mutation plots.
Highly correlated genes for GIMAP8:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIMAP8 | GIMAP4 | 0.847134 | 7 | 0 | 7 |
| GIMAP8 | GIMAP5 | 0.818071 | 4 | 0 | 4 |
| GIMAP8 | GIMAP7 | 0.79886 | 8 | 0 | 8 |
| GIMAP8 | SH3BP5 | 0.797755 | 3 | 0 | 3 |
| GIMAP8 | FLI1 | 0.783113 | 7 | 0 | 6 |
| GIMAP8 | GIMAP6 | 0.780596 | 7 | 0 | 6 |
| GIMAP8 | TMEM50A | 0.769168 | 3 | 0 | 3 |
| GIMAP8 | MYCT1 | 0.765203 | 5 | 0 | 4 |
| GIMAP8 | NPAT | 0.756346 | 3 | 0 | 3 |
| GIMAP8 | LMCD1 | 0.743497 | 3 | 0 | 3 |
| GIMAP8 | ARHGAP15 | 0.737184 | 4 | 0 | 4 |
| GIMAP8 | RPS9 | 0.73709 | 3 | 0 | 3 |
| GIMAP8 | DOCK10 | 0.731301 | 5 | 0 | 4 |
| GIMAP8 | CCDC102B | 0.726968 | 3 | 0 | 3 |
| GIMAP8 | PZP | 0.726855 | 4 | 0 | 4 |
| GIMAP8 | KL | 0.723261 | 3 | 0 | 3 |
| GIMAP8 | IGFBP5 | 0.718056 | 5 | 0 | 5 |
| GIMAP8 | EBF1 | 0.716593 | 5 | 0 | 5 |
| GIMAP8 | TNFSF12 | 0.715916 | 3 | 0 | 3 |
| GIMAP8 | ARHGEF6 | 0.714274 | 7 | 0 | 7 |
For details and further investigation, click here
